Gene description for PSMG3
Gene name proteasome (prosome, macropain) assembly chaperone 3
Gene symbol PSMG3
Other names/aliases C7orf48
PAC3
Species Homo sapiens
 Database cross references - PSMG3
ExoCarta ExoCarta_84262
Vesiclepedia VP_84262
Entrez Gene 84262
HGNC 22420
UniProt Q9BT73  
 PSMG3 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for PSMG3
Molecular Function
    protein binding GO:0005515 IPI
    protein-containing complex binding GO:0044877 IDA
    molecular adaptor activity GO:0060090 IMP
Biological Process
    proteasome assembly GO:0043248 IEA
    chaperone-mediated protein complex assembly GO:0051131 IMP
Subcellular Localization
    protein-containing complex GO:0032991 ISS
 Experiment description of studies that identified PSMG3 in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PSMG3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PSMA6 5687
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
2 RIT1 6016
Negative Genetic Homo sapiens
3 ZNHIT1  
Affinity Capture-MS Homo sapiens
4 PSMD6 9861
Affinity Capture-MS Homo sapiens
5 DUXAP10  
Affinity Capture-MS Homo sapiens
6 PSMA4 5685
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 PIFO  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 FAM192A  
Affinity Capture-MS Homo sapiens
9 ATP6V1C1 528
Co-fractionation Homo sapiens
10 NDUFB5 4711
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 FAM218A  
Affinity Capture-MS Homo sapiens
12 PSMG4  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
13 PUM2 23369
Affinity Capture-MS Homo sapiens
14 RPS2P32  
Affinity Capture-MS Homo sapiens
15 VPS26A 9559
Co-fractionation Homo sapiens
16 NOXO1  
Affinity Capture-MS Homo sapiens
17 ZMAT5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 ZNF843  
Affinity Capture-MS Homo sapiens
19 TRMU  
Affinity Capture-MS Homo sapiens
20 PPP2R5C 5527
Co-fractionation Homo sapiens
21 ODF3  
Affinity Capture-MS Homo sapiens
22 IMP3 55272
Affinity Capture-MS Homo sapiens
23 STAT3 6774
Co-fractionation Homo sapiens
24 SOST  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 FOXD4L6  
Affinity Capture-MS Homo sapiens
26 TBC1D15 64786
Co-fractionation Homo sapiens
27 PSMG1 8624
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
28 PSMB9 5698
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 FOXD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 C6orf15  
Affinity Capture-MS Homo sapiens
31 CUL1 8454
Affinity Capture-MS Homo sapiens
32 C7orf33  
Affinity Capture-MS Homo sapiens
33 RPS11 6205
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 C9orf163  
Affinity Capture-MS Homo sapiens
35 PSMB3 5691
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
36 PSME3 10197
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 PSMD1 5707
Affinity Capture-MS Homo sapiens
38 ZNF444  
Affinity Capture-MS Homo sapiens
39 MRPS34 65993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 IL17RE  
Affinity Capture-MS Homo sapiens
41 PSME1 5720
Affinity Capture-MS Homo sapiens
42 AMACR 23600
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 PSMG2 56984
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
44 MRPL51 51258
Affinity Capture-MS Homo sapiens
45 C1orf158  
Affinity Capture-MS Homo sapiens
46 RASL10B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 DNM1L 10059
Co-fractionation Homo sapiens
48 FOXS1  
Affinity Capture-MS Homo sapiens
49 TAP2 6891
Two-hybrid Homo sapiens
50 SIX2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 SLC4A7 9497
Affinity Capture-MS Homo sapiens
52 ZNF747  
Affinity Capture-MS Homo sapiens
53 BCL2L12 83596
Affinity Capture-MS Homo sapiens
54 PPM1E  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 PSMA2 5683
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
56 EGFR 1956
Negative Genetic Homo sapiens
57 PRR27 401137
Affinity Capture-MS Homo sapiens
58 GADD45GIP1  
Affinity Capture-MS Homo sapiens
59 THAP8  
Affinity Capture-MS Homo sapiens
60 ARFIP1 27236
Co-fractionation Homo sapiens
61 CTSG 1511
Affinity Capture-MS Homo sapiens
62 A1CF  
Affinity Capture-MS Homo sapiens
63 RPL35A 6165
Affinity Capture-MS Homo sapiens
64 SIRT6  
Affinity Capture-MS Homo sapiens
65 APBB3  
Affinity Capture-MS Homo sapiens
66 PSMB5 5693
Reconstituted Complex Homo sapiens
67 KRAS 3845
Negative Genetic Homo sapiens
68 SPATA8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 PSMB1 5689
Reconstituted Complex Homo sapiens
70 FAM181A  
Affinity Capture-MS Homo sapiens
71 PSMC3 5702
Affinity Capture-MS Homo sapiens
72 DCDC2B  
Affinity Capture-MS Homo sapiens
73 ZNF785  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
74 CA10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 NMI  
Co-fractionation Homo sapiens
76 C15orf53  
Affinity Capture-MS Homo sapiens
77 PSMB7 5695
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 POMP  
Affinity Capture-MS Homo sapiens
79 AVPI1  
Affinity Capture-MS Homo sapiens
80 SHFM1 7979
Affinity Capture-MS Homo sapiens
81 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
82 FAM120AOS  
Affinity Capture-MS Homo sapiens
83 SHMT2 6472
Co-fractionation Homo sapiens
84 PMS2P5  
Affinity Capture-MS Homo sapiens
85 PSMA1 5682
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
86 CYP27B1  
Affinity Capture-MS Homo sapiens
87 PSMA5 5686
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
88 PSMA7 5688
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
89 PSMF1 9491
Affinity Capture-MS Homo sapiens
90 RPP21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 HOXC12  
Affinity Capture-MS Homo sapiens
92 CCDC69 26112
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 IGFBP6 3489
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 PSMB4 5692
Reconstituted Complex Homo sapiens
95 PSMC4 5704
Affinity Capture-MS Homo sapiens
96 DUX3  
Affinity Capture-MS Homo sapiens
97 C9orf106  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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