Gene description for ABHD11
Gene name abhydrolase domain containing 11
Gene symbol ABHD11
Other names/aliases PP1226
WBSCR21
Species Homo sapiens
 Database cross references - ABHD11
ExoCarta ExoCarta_83451
Vesiclepedia VP_83451
Entrez Gene 83451
HGNC 16407
UniProt Q8NFV4  
 ABHD11 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Squamous carcinoma cells 20124223    
 Gene ontology annotations for ABHD11
Molecular Function
    protein binding GO:0005515 IPI
    lipase activity GO:0016298 IDA
    carboxylic ester hydrolase activity GO:0052689 IBA
Biological Process
    lipid metabolic process GO:0006629 IBA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 IDA
    mitochondrial matrix GO:0005759 IDA
    oxoglutarate dehydrogenase complex GO:0045252 IDA
 Experiment description of studies that identified ABHD11 in exosomes
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 191
MISEV standards
Biophysical techniques
Alix|CD81|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ABHD11
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MORN3  
Two-hybrid Homo sapiens
2 AK4 205
Co-fractionation Homo sapiens
3 ACAD8 27034
Affinity Capture-MS Homo sapiens
4 MTHFD2 10797
Co-fractionation Homo sapiens
5 SUMF2 25870
Co-fractionation Homo sapiens
6 ECH1 1891
Affinity Capture-MS Homo sapiens
7 UQCRFS1 7386
Affinity Capture-MS Homo sapiens
8 RUSC1  
Two-hybrid Homo sapiens
9 PRR35  
Two-hybrid Homo sapiens
10 AK2 204
Co-fractionation Homo sapiens
11 NIPSNAP3A  
Affinity Capture-MS Homo sapiens
12 GCA 25801
Two-hybrid Homo sapiens
13 GUK1 2987
Co-fractionation Homo sapiens
14 FAS 355
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 YTHDF1 54915
Two-hybrid Homo sapiens
16 PTRHD1 391356
Co-fractionation Homo sapiens
17 WWOX 51741
Two-hybrid Homo sapiens
18 VAC14 55697
Two-hybrid Homo sapiens
19 S100A6 6277
Affinity Capture-MS Homo sapiens
20 NME4 4833
Affinity Capture-MS Homo sapiens
21 TRIAP1  
Co-fractionation Homo sapiens
22 ANXA1 301
Co-fractionation Homo sapiens
23 MGAT5B  
Two-hybrid Homo sapiens
24 FOXA1  
Affinity Capture-MS Homo sapiens
25 MDFI  
Two-hybrid Homo sapiens
26 BOLA3  
Affinity Capture-MS Homo sapiens
27 LAMTOR2 28956
Co-fractionation Homo sapiens
28 FAHD1 81889
Affinity Capture-MS Homo sapiens
29 DHRS4 10901
Affinity Capture-MS Homo sapiens
30 TXNDC12 51060
Co-fractionation Homo sapiens
31 PEBP1 5037
Co-fractionation Homo sapiens
32 BOLA1 51027
Affinity Capture-MS Homo sapiens
33 CSTF2 1478
Two-hybrid Homo sapiens
34 ZIC1  
Two-hybrid Homo sapiens
35 APP 351
Reconstituted Complex Homo sapiens
36 YARS2  
Affinity Capture-MS Homo sapiens
37 SH3BGRL3 83442
Co-fractionation Homo sapiens
38 HCCS 3052
Co-fractionation Homo sapiens
39 CYP51A1 1595
Co-fractionation Homo sapiens
40 TMEM173  
Affinity Capture-MS Homo sapiens
41 CHCHD4  
Affinity Capture-MS Homo sapiens
42 DOK6  
Two-hybrid Homo sapiens
43 ABHD11 83451
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 PRDX6 9588
Co-fractionation Homo sapiens
45 SPR 6697
Co-fractionation Homo sapiens
46 LACTB2 51110
Co-fractionation Homo sapiens
47 OSTM1 28962
Affinity Capture-MS Homo sapiens
48 WIPI1 55062
Affinity Capture-MS Homo sapiens
49 ANKRD11 29123
Two-hybrid Homo sapiens
50 COL10A1  
Affinity Capture-MS Homo sapiens
51 C1QBP 708
Affinity Capture-MS Homo sapiens
52 LDLR 3949
Positive Genetic Homo sapiens
53 PGM1 5236
Co-fractionation Homo sapiens
54 USHBP1  
Two-hybrid Homo sapiens
55 VPS37C 55048
Two-hybrid Homo sapiens
56 PRKAB2 5565
Two-hybrid Homo sapiens
57 HOGA1  
Affinity Capture-MS Homo sapiens
58 LYPLA1 10434
Co-fractionation Homo sapiens
59 PROP1  
Two-hybrid Homo sapiens
60 VENTX  
Two-hybrid Homo sapiens
61 COMT 1312
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which ABHD11 is involved
No pathways found





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