Gene description for THRB
Gene name	thyroid hormone receptor, beta
Gene symbol	THRB
Other names/aliases	C-ERBA-2 C-ERBA-BETA ERBA2 GRTH NR1A2 PRTH THR1 THRB1 THRB2
Species	Homo sapiens
Database cross references - THRB
ExoCarta	ExoCarta_7068
Vesiclepedia	VP_7068
Entrez Gene	7068
HGNC	11799
MIM	190160
UniProt	P10828
THRB identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocytes	26054723

Gene ontology annotations for THRB

Molecular Function     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 ISA     transcription coactivator binding GO:0001223 IPI     DNA binding GO:0003677 TAS     DNA-binding transcription factor activity GO:0003700 NAS     nuclear receptor activity GO:0004879 IBA     nuclear receptor activity GO:0004879 IDA     protein binding GO:0005515 IPI     zinc ion binding GO:0008270 IEA     enzyme binding GO:0019899 IPI     chromatin DNA binding GO:0031490 IEA     thyroid hormone binding GO:0070324 IDA     sequence-specific double-stranded DNA binding GO:1990837 IDA Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IBA     thyroid hormone receptor signaling pathway GO:0002154 IBA     positive regulation of thyroid hormone receptor signaling pathway GO:0002157 IDA     DNA-templated transcription GO:0006351 TAS     sensory perception of sound GO:0007605 IEA     negative regulation of female receptivity GO:0007621 IEA     regulation of heart contraction GO:0008016 IEA     female courtship behavior GO:0008050 IEA     cell differentiation GO:0030154 IBA     mRNA transcription by RNA polymerase II GO:0042789 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IBA     positive regulation of transcription by RNA polymerase II GO:0045944 IDA     retinal cone cell development GO:0046549 IEA     retinoic acid receptor signaling pathway GO:0048384 IBA     type I pneumocyte differentiation GO:0060509 IEA     cellular response to thyroid hormone stimulus GO:0097067 IDA     retinal cone cell apoptotic process GO:0097474 IEA Subcellular Localization     chromatin GO:0000785 ISA     nucleus GO:0005634 IBA     nucleoplasm GO:0005654 TAS     nuclear body GO:0016604 IDA     RNA polymerase II transcription regulator complex GO:0090575 IBA     RNA polymerase II transcription regulator complex GO:0090575 IDA