Gene description for Tmed10
Gene name transmembrane emp24-like trafficking protein 10 (yeast)
Gene symbol Tmed10
Other names/aliases 1110014C03Rik
Tmp21
p23
p24delta1
Species Mus musculus
 Database cross references - Tmed10
ExoCarta ExoCarta_68581
Entrez Gene 68581
UniProt Q9D1D4  
 Tmed10 identified in exosomes derived from the following tissue/cell type
Pancreatic cells 19351151    
 Gene ontology annotations for Tmed10
Molecular Function
    protein complex binding GO:0032403 ISO
    syntaxin binding GO:0019905 ISO
Biological Process
    protein transport GO:0015031 IEA
    vesicle-mediated transport GO:0016192 IEA
    transport GO:0006810 IEA
    regulation of beta-amyloid formation GO:1902003 ISO
    intracellular protein transport GO:0006886 TAS
    COPI-coated vesicle budding GO:0035964 ISO
    protein oligomerization GO:0051259 ISO
    Golgi organization GO:0007030 ISO
Subcellular Localization
    Golgi membrane GO:0000139 ISO
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 ISO
    cell GO:0005623 TAS
    COPI-coated vesicle GO:0030137 ISO
    intracellular GO:0005622 TAS
    endoplasmic reticulum GO:0005783 ISO
    intracellular membrane-bounded organelle GO:0043231 ISO
    gamma-secretase complex GO:0070765 ISO
    Golgi apparatus GO:0005794 ISO
    zymogen granule membrane GO:0042589 ISO
    secretory granule membrane GO:0030667 IDA
    plasma membrane GO:0005886 ISO
    cis-Golgi network GO:0005801 ISS
    cytoplasmic vesicle GO:0031410 IEA
    extracellular exosome GO:0070062 ISO
    membrane GO:0016020 IEA
    integral component of membrane GO:0016021 ISO
 Experiment description of studies that identified Tmed10 in exosomes
1
Experiment ID 188
ISEV standards
EM
EV Biophysical techniques
GAPDH|UCHL1|HSP90
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19351151    
Organism Mus musculus
Experiment description Characterization of vesicles secreted from insulinoma NIT-1 cells.
Authors Lee HS, Jeong J, Lee KJ.
Journal name J Proteome Res
Publication year 2009
Sample Pancreatic cells
Sample name Pancreatic beta cell (NIT-1)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Tmed10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tmed10 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here