Gene description for BRMS1
Gene name breast cancer metastasis suppressor 1
Gene symbol BRMS1
Other names/aliases -
Species Homo sapiens
 Database cross references - BRMS1
ExoCarta ExoCarta_25855
Entrez Gene 25855
HGNC 17262
MIM 606259
UniProt Q9HCU9  
 BRMS1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for BRMS1
Molecular Function
    histone deacetylase activity GO:0004407 IBA
    NF-kappaB binding GO:0051059 IDA
    histone deacetylase binding GO:0042826 IBA
    protein binding GO:0005515 IPI
Biological Process
    chromatin organization GO:0006325 TAS
    positive regulation of protein deacetylation GO:0090312 IDA
    apoptotic process GO:0006915 IEA
    transcription, DNA-templated GO:0006351 IEA
    negative regulation of transcription, DNA-templated GO:0045892 IDA
    positive regulation of anoikis GO:2000210 IMP
    negative regulation of NF-kappaB transcription factor activity GO:0032088 IDA
    histone deacetylation GO:0016575 IBA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IBA
Subcellular Localization
    nucleus GO:0005634 IDA
    Sin3-type complex GO:0070822 IBA
    cytoplasm GO:0005737 IDA
    nucleoplasm GO:0005654 TAS
 Experiment description of studies that identified BRMS1 in exosomes
1
Experiment ID 126
ISEV standards
EV Biophysical techniques
GAPDH
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for BRMS1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EEF1A1 1915
Two-hybrid Homo sapiens
2 GOLGB1 2804
Two-hybrid Homo sapiens
3 RIF1  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which BRMS1 is involved
PathwayEvidenceSource
HDACs deacetylate histones TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here