Experiment description of studies that identified ATXN7L1 in exosomes

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for ATXN7L1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 TARBP1 6894 Affinity Capture-MS Homo sapiens 2 SHKBP1   Affinity Capture-MS Homo sapiens 3 IKBKAP 8518 Affinity Capture-MS Homo sapiens 4 PHF1   Two-hybrid Homo sapiens 5 CERK 64781 Affinity Capture-MS Homo sapiens 6 SPIN3   Affinity Capture-MS Homo sapiens 7 RAD50 10111 Affinity Capture-MS Homo sapiens 8 GFER   Affinity Capture-MS Homo sapiens 9 KIF3A 11127 Affinity Capture-MS Homo sapiens 10 KAT2A   Affinity Capture-MS Homo sapiens 11 RAB1A 5861 Affinity Capture-MS Homo sapiens 12 MUS81   Synthetic Growth Defect Homo sapiens 13 CDKN2C   Affinity Capture-MS Homo sapiens 14 TTC32   Affinity Capture-MS Homo sapiens 15 KCTD9   Affinity Capture-MS Homo sapiens 16 RHOC 389 Affinity Capture-MS Homo sapiens 17 USP22 23326 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 APPBP2   Affinity Capture-MS Homo sapiens 19 DDX19B 11269 Affinity Capture-MS Homo sapiens 20 EDC4 23644 Affinity Capture-MS Homo sapiens 21 VEZF1   Two-hybrid Homo sapiens 22 ELP3 55140 Affinity Capture-MS Homo sapiens 23 IFT122 55764 Affinity Capture-MS Homo sapiens 24 PLCG1 5335 Affinity Capture-MS Homo sapiens 25 ALDH16A1 126133 Affinity Capture-MS Homo sapiens 26 SSPO 23145 Two-hybrid Homo sapiens 27 THNSL1 79896 Affinity Capture-MS Homo sapiens 28 TRIM55   Two-hybrid Homo sapiens 29 ZBTB10 65986 Affinity Capture-MS Homo sapiens 30 PPP2R2D 55844 Affinity Capture-MS Homo sapiens 31 RFWD2   Affinity Capture-MS Homo sapiens 32 LONRF2   Affinity Capture-MS Homo sapiens 33 WDR4 10785 Affinity Capture-MS Homo sapiens 34 PPP2CA 5515 Affinity Capture-MS Homo sapiens 35 ROR2 4920 Two-hybrid Homo sapiens 36 SP4   Two-hybrid Homo sapiens 37 DHX40   Affinity Capture-MS Homo sapiens 38 MEIS2   Affinity Capture-MS Homo sapiens 39 DDX11 1663 Affinity Capture-MS Homo sapiens 40 MAU2   Affinity Capture-MS Homo sapiens 41 PDLIM5 10611 Affinity Capture-MS Homo sapiens 42 TYSND1   Affinity Capture-MS Homo sapiens 43 MYC   Proximity Label-MS Homo sapiens 44 MAPK9 5601 Affinity Capture-MS Homo sapiens 45 GABARAP 11337 Affinity Capture-MS Homo sapiens 46 APAF1 317 Affinity Capture-MS Homo sapiens 47 TAF12   Affinity Capture-MS Homo sapiens 48 UPF1 5976 Affinity Capture-MS Homo sapiens 49 MRPL23 6150 Affinity Capture-MS Homo sapiens 50 NIPBL 25836 Affinity Capture-MS Homo sapiens 51 PHF23 79142 Affinity Capture-MS Homo sapiens 52 PDE4DIP 9659 Affinity Capture-MS Homo sapiens 53 CCDC101   Affinity Capture-MS Homo sapiens 54 KLF6   Proximity Label-MS Homo sapiens 55 PUSL1   Affinity Capture-MS Homo sapiens 56 ATXN7L3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 ENY2 56943 Affinity Capture-MS Homo sapiens 58 GNPAT 8443 Affinity Capture-MS Homo sapiens 59 DET1   Affinity Capture-MS Homo sapiens 60 VENTX   Two-hybrid Homo sapiens 61 FBXO38 81545 Affinity Capture-MS Homo sapiens 62 PRKAB1 5564 Affinity Capture-MS Homo sapiens 63 KRT31 3881 Two-hybrid Homo sapiens 64 HSD17B8   Affinity Capture-MS Homo sapiens 65 WDHD1   Affinity Capture-MS Homo sapiens 66 LANCL2 55915 Affinity Capture-MS Homo sapiens 67 USO1 8615 Affinity Capture-MS Homo sapiens 68 TRIM63   Two-hybrid Homo sapiens 69 USP27X   Affinity Capture-MS Homo sapiens 70 ATG7 10533 Affinity Capture-MS Homo sapiens 71 KRTAP10-9   Two-hybrid Homo sapiens View the network

Pathways in which ATXN7L1 is involved

No pathways found