Gene ontology annotations for UBE2V2
Experiment description of studies that identified UBE2V2 in sEVs
1
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
5
Experiment ID
20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
17956143
Organism
Homo sapiens
Experiment description
Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors
"Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name
JPR
Publication year
2007
Sample
Colorectal cancer cells
Sample name
HT29
Isolation/purification methods
Differential centrifugation Sucrose density gradient Diafiltration
Flotation density
1.16 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
6
Experiment ID
207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DKO-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
7
Experiment ID
208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
Dks-8
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
8
Experiment ID
209
MISEV standards
✘
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DLD-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
9
Experiment ID
231
MISEV standards
✘
Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein Lipids
Methods used in the study
Western blotting Mass spectrometry
10
Experiment ID
232
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
11
Experiment ID
233
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
"Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
12
Experiment ID
274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25844599
Organism
Homo sapiens
Experiment description
Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors
"Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name
Oncotarget
Publication year
2015
Sample
Prostate cancer cells
Sample name
DU145 - Docetaxel resistant
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.18 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Flow cytometry Western blotting
Protein-protein interactions for UBE2V2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
STUB1
10273
Co-fractionation
Homo sapiens
2
SIAH1
Two-hybrid
Homo sapiens
3
DZIP3
Two-hybrid
Homo sapiens
4
TRIM5
85363
Two-hybrid
Homo sapiens
5
YBX1
4904
Affinity Capture-MS
Homo sapiens
6
SEC23A
10484
Co-fractionation
Homo sapiens
7
UBE2N
7334
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-MS
Homo sapiens
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Co-crystal Structure
Homo sapiens
Affinity Capture-MS
Homo sapiens
Co-crystal Structure
Homo sapiens
Reconstituted Complex
Homo sapiens
Two-hybrid
Homo sapiens
Co-crystal Structure
Homo sapiens
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
Reconstituted Complex
Homo sapiens
Co-crystal Structure
Homo sapiens
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Reconstituted Complex
Homo sapiens
Co-fractionation
Homo sapiens
Co-crystal Structure
Homo sapiens
Reconstituted Complex
Homo sapiens
Co-crystal Structure
Homo sapiens
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
8
FASN
2194
Negative Genetic
Homo sapiens
9
EFR3A
23167
Affinity Capture-MS
Homo sapiens
10
XIAP
Two-hybrid
Homo sapiens
11
TRAF2
7186
Reconstituted Complex
Homo sapiens
12
ZRANB2
9406
Co-fractionation
Homo sapiens
13
USP9X
8239
Co-fractionation
Homo sapiens
14
RNF11
26994
Affinity Capture-MS
Homo sapiens
15
ATP6V1B2
526
Co-fractionation
Homo sapiens
16
RPS21
6227
Co-fractionation
Homo sapiens
17
RC3H2
Reconstituted Complex
Homo sapiens
18
UBE2V1
7335
Co-fractionation
Homo sapiens
Affinity Capture-MS
Homo sapiens
19
UBE2M
9040
Co-fractionation
Homo sapiens
20
CD2BP2
10421
Co-fractionation
Homo sapiens
21
ZPR1
8882
Co-fractionation
Homo sapiens
22
UBE2L3
7332
Co-fractionation
Homo sapiens
23
MKRN3
Two-hybrid
Homo sapiens
24
RAD23B
5887
Co-fractionation
Homo sapiens
25
RNF144A
Two-hybrid
Homo sapiens
26
POLK
Affinity Capture-MS
Homo sapiens
27
HLTF
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Reconstituted Complex
Homo sapiens
28
SHPRH
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
29
CHCHD2
Affinity Capture-MS
Homo sapiens
30
TIGD6
Affinity Capture-MS
Homo sapiens
31
ZNRF1
Two-hybrid
Homo sapiens
32
UBC
7316
Co-crystal Structure
Homo sapiens
Reconstituted Complex
Homo sapiens
Co-crystal Structure
Homo sapiens
Co-crystal Structure
Homo sapiens
Reconstituted Complex
Homo sapiens
33
EGFR
1956
PCA
Homo sapiens
34
MOB4
25843
Two-hybrid
Homo sapiens
35
Ube2n
93765
Reconstituted Complex
Mus musculus
36
OTUB1
55611
Reconstituted Complex
Homo sapiens
37
IGSF21
Two-hybrid
Homo sapiens
38
ZFYVE19
84936
Co-fractionation
Homo sapiens
39
SVIL
6840
Affinity Capture-MS
Homo sapiens
40
LRIF1
Two-hybrid
Homo sapiens
41
UBXN7
26043
Co-fractionation
Homo sapiens
42
VPS26A
9559
Co-fractionation
Homo sapiens
43
ZYX
7791
Co-fractionation
Homo sapiens
44
TUBA1B
10376
Affinity Capture-MS
Homo sapiens
45
UBE2B
7320
Co-fractionation
Homo sapiens
46
BCL10
Reconstituted Complex
Homo sapiens
47
MYO5B
4645
Affinity Capture-MS
Homo sapiens
48
PRPF38A
84950
Affinity Capture-MS
Homo sapiens
49
MYO1E
4643
Affinity Capture-MS
Homo sapiens
50
SSSCA1
10534
Co-fractionation
Homo sapiens
51
RNF8
Reconstituted Complex
Homo sapiens
52
HNRNPA1L2
144983
Affinity Capture-MS
Homo sapiens
53
MALT1
10892
Reconstituted Complex
Homo sapiens
54
TRIM32
22954
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
Two-hybrid
Homo sapiens
55
RAI14
26064
Affinity Capture-MS
Homo sapiens
56
TTC9C
283237
Co-fractionation
Homo sapiens
57
ACTB
60
Co-fractionation
Homo sapiens
58
MINPP1
9562
Affinity Capture-MS
Homo sapiens
59
RNF2
Two-hybrid
Homo sapiens
60
Rtfdc1
Affinity Capture-MS
Mus musculus
61
ETFA
2108
Co-fractionation
Homo sapiens
62
ARGLU1
Affinity Capture-MS
Homo sapiens
63
RC3H1
149041
Reconstituted Complex
Homo sapiens
64
MPRIP
23164
Affinity Capture-MS
Homo sapiens
65
TTLL12
23170
Co-fractionation
Homo sapiens
66
USP34
9736
Co-fractionation
Homo sapiens
67
RHOA
387
Affinity Capture-MS
Homo sapiens
68
UBXN1
51035
Co-fractionation
Homo sapiens
69
UFM1
51569
Co-fractionation
Homo sapiens
70
CPLX1
10815
Co-fractionation
Homo sapiens
71
LRCH3
84859
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which UBE2V2 is involved