Gene description for SPN
Gene name	sialophorin
Gene symbol	SPN
Other names/aliases	CD43 GALGP GPL115 LSN
Species	Homo sapiens
Database cross references - SPN
ExoCarta	ExoCarta_6693
Vesiclepedia	VP_6693
Entrez Gene	6693
HGNC	11249
MIM	182160
UniProt	P16150
SPN identified in exosomes derived from the following tissue/cell type
B cells	20458337
B cells	20458337
B cells	20458337
Platelets	25332113
Platelets	25332113
Platelets	25332113
Thymus	23844026

Gene ontology annotations for SPN

Molecular Function     transmembrane signaling receptor activity GO:0004888 IEA     protein binding GO:0005515 IPI     Hsp70 protein binding GO:0030544 IPI     heat shock protein binding GO:0031072 IBA     heat shock protein binding GO:0031072 IPI Biological Process     response to protozoan GO:0001562 IEA     negative regulation of type IV hypersensitivity GO:0001808 IEA     T-helper 1 cell lineage commitment GO:0002296 IDA     chemotaxis GO:0006935 TAS     immune response GO:0006955 TAS     cellular defense response GO:0006968 TAS     negative regulation of cell adhesion GO:0007162 TAS     establishment or maintenance of cell polarity GO:0007163 TAS     signal transduction GO:0007165 TAS     cell surface receptor signaling pathway GO:0007166 IBA     T cell costimulation GO:0031295 IEA     positive regulation of tumor necrosis factor production GO:0032760 IDA     T cell proliferation GO:0042098 IEA     positive regulation of T cell proliferation GO:0042102 IEA     negative regulation of T cell proliferation GO:0042130 ISS     defense response to bacterium GO:0042742 IBA     defense response to bacterium GO:0042742 IDA     negative thymic T cell selection GO:0045060 IEA     regulation of defense response to virus GO:0050688 IEA     regulation of immune response GO:0050776 IBA     leukocyte tethering or rolling GO:0050901 ISS     apoptotic signaling pathway GO:0097190 IEA     regulation of T cell migration GO:2000404 ISS     positive regulation of T cell migration GO:2000406 ISS Subcellular Localization     uropod GO:0001931 ISS     basement membrane GO:0005604 IEA     extracellular space GO:0005615 IDA     plasma membrane GO:0005886 TAS     microvillus GO:0005902 ISS     external side of plasma membrane GO:0009897 IBA     cell surface GO:0009986 IDA     membrane GO:0016020 HDA     PML body GO:0016605 IEA     extracellular exosome GO:0070062 HDA