Gene description for ANKS1A
Gene name ankyrin repeat and sterile alpha motif domain containing 1A
Gene symbol ANKS1A
Other names/aliases ANKS1
Species Homo sapiens
 Database cross references - ANKS1A
ExoCarta ExoCarta_23294
Entrez Gene 23294
HGNC 20961
MIM 608994
UniProt Q92625  
 ANKS1A identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for ANKS1A
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    ephrin receptor signaling pathway GO:0048013 ISS
    substrate-dependent cell migration GO:0006929 ISS
    neuron remodeling GO:0016322 ISS
Subcellular Localization
    cytoplasm GO:0005737 IDA
    neuron projection GO:0043005 ISS
    nucleoplasm GO:0005654 IDA
 Experiment description of studies that identified ANKS1A in exosomes
Experiment ID 224
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for ANKS1A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SFN 2810
Affinity Capture-MS Homo sapiens
2 YWHAG 7532
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ANKS1A is involved
No pathways found

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