Gene description for RERE
Gene name arginine-glutamic acid dipeptide (RE) repeats
Gene symbol RERE
Other names/aliases ARG
ARP
ATN1L
DNB1
Species Homo sapiens
 Database cross references - RERE
ExoCarta ExoCarta_473
Vesiclepedia VP_473
Entrez Gene 473
HGNC 9965
MIM 605226
UniProt Q9P2R6  
 RERE identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for RERE
Molecular Function
    chromatin binding GO:0003682 IEA
    transcription coactivator activity GO:0003713 IEA
    transcription corepressor activity GO:0003714 IBA
    protein binding GO:0005515 IPI
    sequence-specific DNA binding GO:0043565 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    chromatin remodeling GO:0006338 IEA
    cerebellar Purkinje cell layer maturation GO:0021691 IEA
    cerebellar granule cell precursor proliferation GO:0021930 IEA
    radial glia guided migration of Purkinje cell GO:0021942 IEA
    negative regulation of DNA-templated transcription GO:0045892 IEA
    positive regulation of DNA-templated transcription GO:0045893 IEA
    branching morphogenesis of a nerve GO:0048755 IEA
    dendrite morphogenesis GO:0048813 IEA
Subcellular Localization
    histone deacetylase complex GO:0000118 IEA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nuclear body GO:0016604 IDA
 Experiment description of studies that identified RERE in sEVs
1
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for RERE
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 YEATS2  
Affinity Capture-MS Homo sapiens
2 MCRS1  
Affinity Capture-MS Homo sapiens
3 ALG13 79868
Two-hybrid Homo sapiens
4 ASH2L 9070
Affinity Capture-MS Homo sapiens
5 FASN 2194
Positive Genetic Homo sapiens
6 PSMA3 5684
Two-hybrid Homo sapiens
7 WDR5 11091
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 HDAC2 3066
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
9 KAT8  
Affinity Capture-MS Homo sapiens
10 RBFOX2 23543
Two-hybrid Homo sapiens
11 KMT2A  
Affinity Capture-MS Homo sapiens
12 HIST2H3C 126961
Biochemical Activity Homo sapiens
13 KANSL1  
Affinity Capture-MS Homo sapiens
14 Wdr5  
Affinity Capture-MS Mus musculus
15 KMT2B  
Affinity Capture-MS Homo sapiens
16 KDM6A  
Affinity Capture-MS Homo sapiens
17 CCDC120  
Two-hybrid Homo sapiens
18 PRRC2A 7916
Two-hybrid Homo sapiens
19 RPL37A 6168
Affinity Capture-MS Homo sapiens
20 PLSCR1 5359
Two-hybrid Homo sapiens
21 HCFC1 3054
Affinity Capture-MS Homo sapiens
22 PHF20L1  
Affinity Capture-MS Homo sapiens
23 BUB3 9184
Affinity Capture-MS Homo sapiens
24 PHIP 55023
Affinity Capture-MS Homo sapiens
25 CDO1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 CSRP2BP  
Affinity Capture-MS Homo sapiens
27 ZZZ3  
Affinity Capture-MS Homo sapiens
28 TLX3  
Proximity Label-MS Homo sapiens
29 MEN1 4221
Affinity Capture-MS Homo sapiens
30 HCFC2  
Affinity Capture-MS Homo sapiens
31 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
32 VHL  
Two-hybrid Homo sapiens
33 HDAC1 3065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
34 Act5C  
Reconstituted Complex Drosophila melanogaster
35 KANSL2  
Affinity Capture-MS Homo sapiens
36 KANSL3  
Affinity Capture-MS Homo sapiens
37 TAF1  
Affinity Capture-MS Homo sapiens
38 PRRC2B  
Two-hybrid Homo sapiens
39 SETD1B 23067
Affinity Capture-MS Homo sapiens
40 PHF20  
Affinity Capture-MS Homo sapiens
41 KRTAP6-2  
Two-hybrid Homo sapiens
42 DIABLO 56616
Proximity Label-MS Homo sapiens
43 SETD1A 9739
Affinity Capture-MS Homo sapiens
44 DPY30 84661
Affinity Capture-MS Homo sapiens
45 KRTAP4-12  
Two-hybrid Homo sapiens
46 ZNF620  
Affinity Capture-MS Homo sapiens
47 KRTAP12-4  
Two-hybrid Homo sapiens
48 ATN1  
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
49 CBFA2T2  
Two-hybrid Homo sapiens
50 svp  
Reconstituted Complex Drosophila melanogaster
51 ZNF609  
Affinity Capture-MS Homo sapiens
52 ZNF608  
Affinity Capture-MS Homo sapiens
53 ZMYND8 23613
Two-hybrid Homo sapiens
54 CXXC1  
Affinity Capture-MS Homo sapiens
55 TRIM22 10346
Two-hybrid Homo sapiens
56 PCGF6  
Affinity Capture-MS Homo sapiens
57 EHMT2 10919
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
58 NR2E1  
Reconstituted Complex Homo sapiens
59 MBIP  
Affinity Capture-MS Homo sapiens
60 FBXW7  
Synthetic Lethality Homo sapiens
61 ERG  
Proximity Label-MS Homo sapiens
62 CCDC101  
Affinity Capture-MS Homo sapiens
63 KAT6A  
Two-hybrid Homo sapiens
64 SNRPC 6631
Two-hybrid Homo sapiens
65 AR 367
Proximity Label-MS Homo sapiens
66 LZTR1 8216
Two-hybrid Homo sapiens
67 L3MBTL2  
Affinity Capture-MS Homo sapiens
68 AUTS2  
Affinity Capture-MS Homo sapiens
69 RBBP5 5929
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 SP7  
Proximity Label-MS Homo sapiens
71 EFEMP1 2202
Two-hybrid Homo sapiens
72 ECM1 1893
Two-hybrid Homo sapiens
73 DYNLL1 8655
Affinity Capture-MS Homo sapiens
74 TADA3  
Affinity Capture-MS Homo sapiens
75 EP300 2033
Affinity Capture-Western Homo sapiens
76 EFEMP2 30008
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which RERE is involved
No pathways found





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