Gene description for MMP2
Gene name	matrix metallopeptidase 2
Gene symbol	MMP2
Other names/aliases	CLG4 CLG4A MMP-2 MMP-II MONA TBE-1
Species	Homo sapiens
Database cross references - MMP2
ExoCarta	ExoCarta_4313
Entrez Gene	4313
HGNC	7166
MIM	120360
UniProt	P08253
MMP2 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for MMP2

Molecular Function     serine-type endopeptidase activity GO:0004252 TAS     zinc ion binding GO:0008270 IEA     metallopeptidase activity GO:0008237 IDA     protein binding GO:0005515 IPI     metalloendopeptidase activity GO:0004222 IEA Biological Process     blood vessel maturation GO:0001955 IEA     extracellular matrix organization GO:0030198 TAS     proteolysis GO:0006508 IDA     axon guidance GO:0007411 TAS     ephrin receptor signaling pathway GO:0048013 TAS     positive regulation of innate immune response GO:0045089 IEA     embryo implantation GO:0007566 IEA     intramembranous ossification GO:0001957 IEA     bone trabecula formation GO:0060346 IEA     endodermal cell differentiation GO:0035987 IEP     cellular response to amino acid stimulus GO:0071230 IEA     face morphogenesis GO:0060325 IEA     extracellular matrix disassembly GO:0022617 TAS     collagen catabolic process GO:0030574 TAS     cellular protein metabolic process GO:0044267 TAS     angiogenesis GO:0001525 IEA     response to hypoxia GO:0001666 IEA Subcellular Localization     extracellular region GO:0005576 TAS     mitochondrion GO:0005739 IEA     sarcomere GO:0030017 IEA     plasma membrane GO:0005886 IEA     nucleus GO:0005634 IEA     proteinaceous extracellular matrix GO:0005578 IEA     extracellular space GO:0005615 IDA