Gene description for APOA2
Gene name	apolipoprotein A-II
Gene symbol	APOA2
Other names/aliases	Apo-AII ApoA-II apoAII
Species	Homo sapiens
Database cross references - APOA2
ExoCarta	ExoCarta_336
Entrez Gene	336
HGNC	601
MIM	107670
UniProt	P02652
APOA2 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocellular carcinoma cells	26054723
Hepatocytes	26054723
Plasma	19028452
Platelets	25332113
Platelets	25332113
Platelets	25332113
Saliva	19199708
Urine	19056867

Gene ontology annotations for APOA2

Molecular Function     protein homodimerization activity GO:0042803 IDA     apolipoprotein receptor binding GO:0034190 IPI     phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 IDA     lipid binding GO:0008289 IDA     phosphatidylcholine binding GO:0031210 IDA     cholesterol binding GO:0015485 IDA     lipase inhibitor activity GO:0055102 IDA     protein binding GO:0005515 IPI     protein heterodimerization activity GO:0046982 IPI     phospholipid binding GO:0005543 IDA     lipid transporter activity GO:0005319 IDA     cholesterol transporter activity GO:0017127 IDA     high-density lipoprotein particle binding GO:0008035 IEA     high-density lipoprotein particle receptor binding GO:0070653 IPI Biological Process     acute inflammatory response GO:0002526 IEA     cholesterol homeostasis GO:0042632 IDA     negative regulation of cholesterol transport GO:0032375 IMP     phospholipid catabolic process GO:0009395 IDA     protein oxidation GO:0018158 IDA     cholesterol efflux GO:0033344 IDA     triglyceride-rich lipoprotein particle remodeling GO:0034370 IDA     regulation of protein stability GO:0031647 IDA     response to glucose GO:0009749 IDA     diacylglycerol catabolic process GO:0046340 IDA     negative regulation of lipid catabolic process GO:0050995 IDA     organ regeneration GO:0031100 IEA     protein folding GO:0006457 IDA     reverse cholesterol transport GO:0043691 IDA     phospholipid efflux GO:0033700 IDA     positive regulation of catalytic activity GO:0043085 IDA     response to glucocorticoid GO:0051384 IEA     peptidyl-methionine modification GO:0018206 IDA     positive regulation of lipid catabolic process GO:0050996 IDA     phosphatidylcholine biosynthetic process GO:0006656 IDA     negative regulation of very-low-density lipoprotein particle remodeling GO:0010903 IDA     cellular lipid metabolic process GO:0044255 TAS     regulation of intestinal cholesterol absorption GO:0030300 IEA     small molecule metabolic process GO:0044281 TAS     negative regulation of cytokine secretion involved in immune response GO:0002740 IDA     low-density lipoprotein particle remodeling GO:0034374 IDA     high-density lipoprotein particle clearance GO:0034384 IDA     cholesterol metabolic process GO:0008203 IEA     positive regulation of interleukin-8 biosynthetic process GO:0045416 IDA     retinoid metabolic process GO:0001523 TAS     triglyceride metabolic process GO:0006641 TAS     lipoprotein metabolic process GO:0042157 TAS     response to estrogen GO:0043627 IEA     high-density lipoprotein particle assembly GO:0034380 IDA     negative regulation of cholesterol import GO:0060621 IDA     response to drug GO:0042493 IEA     negative regulation of lipase activity GO:0060192 IDA     phototransduction, visible light GO:0007603 TAS     negative regulation of cholesterol transporter activity GO:0060695 IDA     high-density lipoprotein particle remodeling GO:0034375 IDA     positive regulation of cholesterol esterification GO:0010873 IDA     viral process GO:0016032 IEA Subcellular Localization     endoplasmic reticulum lumen GO:0005788 TAS     high-density lipoprotein particle GO:0034364 IDA     spherical high-density lipoprotein particle GO:0034366 IDA     early endosome GO:0005769 TAS     cytosol GO:0005829 TAS     very-low-density lipoprotein particle GO:0034361 IDA     blood microparticle GO:0072562 IDA     chylomicron GO:0042627 IDA     extracellular region GO:0005576 TAS     extracellular exosome GO:0070062 IDA