Experiment description of studies that identified H19 in sEVs

1 Experiment ID 234 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-C3 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

3 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for H19

Protein Interactor ExoCarta ID Identification method PubMed Species 1 BCLAF1 9774 Protein-RNA Homo sapiens 2 STON2 85439 Protein-RNA Homo sapiens 3 AGO2 27161 Affinity Capture-RNA Homo sapiens 4 FMR1 2332 Protein-RNA Homo sapiens 5 SRSF9 8683 Protein-RNA Homo sapiens 6 SSB 6741 Protein-RNA Homo sapiens 7 PPP1R3E   Protein-RNA Homo sapiens 8 IFIT5 24138 Protein-RNA Homo sapiens 9 WHSC1 7468 Protein-RNA Homo sapiens 10 SRSF8 10929 Protein-RNA Homo sapiens 11 ILF2 3608 Affinity Capture-RNA Homo sapiens Protein-RNA Homo sapiens 12 APEX1 328 Affinity Capture-RNA Homo sapiens 13 TPM1 7168 Protein-RNA Homo sapiens 14 MYO1D 4642 Protein-RNA Homo sapiens 15 PCCA 5095 Protein-RNA Homo sapiens 16 DDX5 1655 Protein-RNA Homo sapiens 17 PCCB 5096 Protein-RNA Homo sapiens 18 SERBP1 26135 Protein-RNA Homo sapiens 19 SRSF10 10772 Protein-RNA Homo sapiens 20 PRKRA 8575 Protein-RNA Homo sapiens 21 ESRP1 54845 Protein-RNA Homo sapiens 22 DSP 1832 Protein-RNA Homo sapiens 23 U2SURP 23350 Protein-RNA Homo sapiens View the network

Pathways in which H19 is involved

No pathways found