Gene description for SLC34A2 |
Gene name |
solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
Gene symbol |
SLC34A2 |
Other names/aliases |
NAPI-3B NAPI-IIb NPTIIb |
Species |
Homo sapiens |
Database cross references - SLC34A2 |
ExoCarta |
ExoCarta_10568 |
Entrez Gene |
10568 |
HGNC |
11020 |
MIM |
604217 |
UniProt |
O95436
|
SLC34A2 identified in exosomes derived from the following tissue/cell type |
Breast milk
|
17641064
|
Ovarian cancer cells
|
23333927
|
Ovarian cancer cells
|
23333927
|
Tracheobronchial cells
|
19190083
|
Gene ontology annotations for SLC34A2 |
|
Experiment description of studies that identified SLC34A2 in exosomes |
1 |
Experiment ID |
48 |
ISEV standards |
✔
EM|IEM
|
EV Biophysical techniques |
✔
HSC70
|
EV Cytosolic markers |
✔
CD63|CD86|MHCII
|
EV Membrane markers |
✔
CANX
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
17641064
|
Organism |
Homo sapiens |
Experiment description |
Exosomes with immune modulatory features are present in human breast milk. |
Authors |
Admyre C, Johansson SM, Qazi KR, Filen JJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S |
Journal name |
JIMMU
|
Publication year |
2007 |
Sample |
Breast milk |
Sample name |
Breast milk - Mature milk |
Isolation/purification methods |
Differential centrifugation Filtration Sucrose density gradient |
Flotation density |
1.10-1.18 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry [QSTAR] Western blotting Immunoelectron Microscopy FACS |
|
|
2 |
Experiment ID |
211 |
ISEV standards |
✔
EM
|
EV Biophysical techniques |
✔
TSG101|Alix
|
EV Cytosolic markers |
✔
EpCAM|TFRC
|
EV Membrane markers |
✔
cytochrome c|GOLGA2
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23333927
|
Organism |
Homo sapiens |
Experiment description |
Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors |
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year |
2013 |
Sample |
Ovarian cancer cells |
Sample name |
IGROV1 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
1.09-1.15 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
3 |
Experiment ID |
212 |
ISEV standards |
✔
CEM
|
EV Biophysical techniques |
✔
TSG101|Alix
|
EV Cytosolic markers |
✔
EpCAM|TFRC
|
EV Membrane markers |
✔
Cytochrome C|GOLGA2
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
23333927
|
Organism |
Homo sapiens |
Experiment description |
Characterization and proteomic analysis of ovarian cancer-derived exosomes. |
Authors |
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K. |
Journal name |
J Proteomics
|
Publication year |
2013 |
Sample |
Ovarian cancer cells |
Sample name |
OVCAR-3 |
Isolation/purification methods |
Differential centrifugation Ultracentrifugation Sucrose density gradient |
Flotation density |
1.09-1.15 g/mL
|
Molecules identified in the study |
Protein |
Methods used in the study |
Mass spectrometry |
|
|
4 |
Experiment ID |
34 |
ISEV standards |
✔
EM|IEM
|
EV Biophysical techniques |
✔
TSG101
|
EV Cytosolic markers |
✔
CD63|MHCI|MHCII
|
EV Membrane markers |
✘
|
EV Negative markers |
✘
|
EV Particle analysis
|
|
Identified molecule |
protein
|
Identification method |
Mass spectrometry
|
PubMed ID |
19190083
|
Organism |
Homo sapiens |
Experiment description |
Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. |
Authors |
Kesimer M, Scull M, Brighton B, Demaria G, Burns K, O'Neal W, Pickles RJ, Sheehan JK |
Journal name |
FASEB
|
Publication year |
2009 |
Sample |
Tracheobronchial cells |
Sample name |
Tracheobronchial epithelial cells |
Isolation/purification methods |
Differential centrifugation Filtration Sucrose density gradient |
Flotation density |
1.16 -1.18 g/mL
|
Molecules identified in the study |
Protein mRNA |
Methods used in the study |
Mass spectrometry [QTOF] Western blotting Immunoelectron Microscopy FACS |
|
|
Protein-protein interactions for SLC34A2 |
|
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
No interactions are found.
|
|
Pathways in which SLC34A2 is involved |
|
|
|