Gene description for KRIT1
Gene name
KRIT1, ankyrin repeat containing
Gene symbol
KRIT1
Other names/aliases
CAM CCM1
Species
Homo sapiens
Database cross references - KRIT1
ExoCarta
ExoCarta_889
Entrez Gene
889
HGNC
1573
MIM
604214
UniProt
O00522
KRIT1 identified in exosomes derived from the following tissue/cell type
Melanoma cells
25950383
Thymus
23844026
Gene ontology annotations for KRIT1
Experiment description of studies that identified KRIT1 in exosomes
1
Experiment ID
260
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
FLOT1|CD81
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25950383
Organism
Homo sapiens
Experiment description
Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors
Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L
Journal name
Pigment Cell Melanoma Res
Publication year
2015
Sample
Melanoma cells
Sample name
1205Lu
Isolation/purification methods
Differential centrifugation Unltracentrifugation Sucrose density gradient
Flotation density
1.13 - 1.19 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for KRIT1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
RELA
Invitro
Homo sapiens
Invivo
Homo sapiens
2
DAPK1
Affinity Capture-Western
Homo sapiens
3
ITGB1BP1
9270
Invivo
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
4
RAP1A
5906
Two-hybrid
Homo sapiens
5
EWSR1
2130
Invitro
Homo sapiens
View the network
image/svg+xml
Pathways in which KRIT1 is involved
No pathways found