Gene description for OCLN
Gene name occludin
Gene symbol OCLN
Other names/aliases BLCPMG
PPP1R115
Species Homo sapiens
 Database cross references - OCLN
ExoCarta ExoCarta_100506658
Vesiclepedia VP_100506658
Entrez Gene 100506658
HGNC 8104
MIM 602876
UniProt Q16625  
 OCLN identified in sEVs derived from the following tissue/cell type
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Prostate cancer cells 25844599    
 Gene ontology annotations for OCLN
Molecular Function
    protein binding GO:0005515 IPI
    protein domain specific binding GO:0019904 IPI
Biological Process
    negative regulation of protein phosphorylation GO:0001933 IMP
    positive regulation of lamellipodium assembly GO:0010592 ISS
    positive regulation of gene expression GO:0010628 IMP
    negative regulation of gene expression GO:0010629 IMP
    regulation of D-glucose transmembrane transport GO:0010827 IMP
    positive regulation of microtubule polymerization GO:0031116 ISS
    maintenance of blood-brain barrier GO:0035633 NAS
    cell-cell junction organization GO:0045216 IMP
    positive regulation of D-glucose import GO:0046326 IMP
    protein-containing complex assembly GO:0065003 TAS
    bicellular tight junction assembly GO:0070830 IBA
    bicellular tight junction assembly GO:0070830 IMP
    positive regulation of wound healing GO:0090303 ISS
    protein localization to cell leading edge GO:1902463 ISS
    positive regulation of blood-brain barrier permeability GO:1905605 IMP
Subcellular Localization
    lysosomal membrane GO:0005765 IDA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    cell-cell junction GO:0005911 IDA
    bicellular tight junction GO:0005923 IBA
    bicellular tight junction GO:0005923 IDA
    apical plasma membrane GO:0016324 IBA
    apicolateral plasma membrane GO:0016327 IEA
    cell junction GO:0030054 IDA
    cell junction GO:0030054 TAS
    endocytic vesicle GO:0030139 IEA
    cell leading edge GO:0031252 ISS
    cytoplasmic vesicle GO:0031410 IBA
    cytoplasmic vesicle GO:0031410 IDA
    protein-containing complex GO:0032991 IDA
    tight junction GO:0070160 IDA
    tight junction GO:0070160 IMP
 Experiment description of studies that identified OCLN in sEVs
1
Experiment ID 1333
MISEV standards
Biophysical techniques
✔
CD81|EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
Western blotting
2
Experiment ID 1335
MISEV standards
Biophysical techniques
✔
EPCAM|CD9
Enriched markers
✘ Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
3
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
4
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
5
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
7
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
 Protein-protein interactions for OCLN
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ITGB1 3688
Proximity Label-MS Homo sapiens
2 GJD3  
Proximity Label-MS Homo sapiens
3 ARHGAP1 392
Proximity Label-MS Homo sapiens
4 WDR6 11180
Proximity Label-MS Homo sapiens
5 UTRN 7402
Proximity Label-MS Homo sapiens
6 RASSF8 11228
Proximity Label-MS Homo sapiens
7 ATG9A 79065
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
8 LLGL1 3996
Proximity Label-MS Homo sapiens
9 PKP2 5318
Proximity Label-MS Homo sapiens
10 CSNK1A1 1452
Reconstituted Complex Homo sapiens
11 JPH1 56704
Proximity Label-MS Homo sapiens
12 SYNE4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
13 C9orf78 51759
Affinity Capture-MS Homo sapiens
14 C1orf226  
Proximity Label-MS Homo sapiens
15 MAP4K4 9448
Proximity Label-MS Homo sapiens
16 LRRN4CL 221091
Affinity Capture-MS Homo sapiens
17 MON2 23041
Proximity Label-MS Homo sapiens
18 CFAP97  
Proximity Label-MS Homo sapiens
19 PLCH1  
Proximity Label-MS Homo sapiens
20 UNC5B 219699
Proximity Label-MS Homo sapiens
21 ABI1 10006
Proximity Label-MS Homo sapiens
22 MAN1A1 4121
Affinity Capture-MS Homo sapiens
23 GPX8 493869
Two-hybrid Homo sapiens
24 SLC12A7 10723
Proximity Label-MS Homo sapiens
25 MPZL2 10205
Affinity Capture-MS Homo sapiens
26 TMEM87A 25963
Proximity Label-MS Homo sapiens
27 KIF14 9928
Proximity Label-MS Homo sapiens
28 NOTCH2 4853
Proximity Label-MS Homo sapiens
29 C19orf38  
Affinity Capture-MS Homo sapiens
30 SH3BP4 23677
Proximity Label-MS Homo sapiens
31 LCTL  
Affinity Capture-MS Homo sapiens
32 EFR3B  
Proximity Label-MS Homo sapiens
33 PDXDC1 23042
Proximity Label-MS Homo sapiens
34 COMTD1 118881
Affinity Capture-MS Homo sapiens
35 CDH1 999
Proximity Label-MS Homo sapiens
36 TANC1 85461
Proximity Label-MS Homo sapiens
37 BACE2 25825
Affinity Capture-MS Homo sapiens
38 GORASP2 26003
Proximity Label-MS Homo sapiens
39 GJB1 2705
Affinity Capture-Western Homo sapiens
40 CSNK1E 1454
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 MPP7 143098
Proximity Label-MS Homo sapiens
42 FLOT2 2319
Proximity Label-MS Homo sapiens
43 PICALM 8301
Proximity Label-MS Homo sapiens
44 TMEM171  
Affinity Capture-MS Homo sapiens
45 IQGAP2 10788
Proximity Label-MS Homo sapiens
46 DST 667
Proximity Label-MS Homo sapiens
47 PALM2  
Proximity Label-MS Homo sapiens
48 EPB41L1 2036
Proximity Label-MS Homo sapiens
49 ARHGAP32  
Proximity Label-MS Homo sapiens
50 EPS15 2060
Affinity Capture-Western Homo sapiens
51 FAM129B 64855
Proximity Label-MS Homo sapiens
52 SIGLECL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 SPECC1 92521
Proximity Label-MS Homo sapiens
54 CDCA3 83461
Proximity Label-MS Homo sapiens
55 NBEA  
Proximity Label-MS Homo sapiens
56 DUOXA2  
Affinity Capture-MS Homo sapiens
57 ADD3 120
Proximity Label-MS Homo sapiens
58 ERBB2IP 55914
Proximity Label-MS Homo sapiens
59 DLG1 1739
Proximity Label-MS Homo sapiens
60 LMTK2 22853
Proximity Label-MS Homo sapiens
61 KLRG2 346689
Affinity Capture-MS Homo sapiens
62 KCNB2  
Proximity Label-MS Homo sapiens
63 SNX9 51429
Proximity Label-MS Homo sapiens
64 TJP2 9414
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
65 ABCC1 4363
Proximity Label-MS Homo sapiens
66 ZER1 10444
Affinity Capture-MS Homo sapiens
67 DZIP1  
Proximity Label-MS Homo sapiens
68 ENTPD2 954
Affinity Capture-MS Homo sapiens
69 MAP4K3 8491
Proximity Label-MS Homo sapiens
70 CTNNA1 1495
Proximity Label-MS Homo sapiens
71 KIDINS220 57498
Proximity Label-MS Homo sapiens
72 EFNB2 1948
Proximity Label-MS Homo sapiens
73 PDE8A 5151
Proximity Label-MS Homo sapiens
74 GOLGB1 2804
Proximity Label-MS Homo sapiens
75 SLC4A2 6522
Proximity Label-MS Homo sapiens
76 GPRIN3  
Proximity Label-MS Homo sapiens
77 DVL1 1855
Proximity Label-MS Homo sapiens
78 TP53BP2  
Proximity Label-MS Homo sapiens
79 PSD3 23362
Proximity Label-MS Homo sapiens
80 STK16 8576
Affinity Capture-MS Homo sapiens
81 SLC18A1  
Affinity Capture-MS Homo sapiens
82 TGFBR2 7048
Affinity Capture-Western Homo sapiens
83 RAB11FIP5 26056
Proximity Label-MS Homo sapiens
84 SCYL3 57147
Proximity Label-MS Homo sapiens
85 MACF1 23499
Proximity Label-MS Homo sapiens
86 CD1B 910
Affinity Capture-MS Homo sapiens
87 LCK 3932
Proximity Label-MS Homo sapiens
88 SPTBN2 6712
Proximity Label-MS Homo sapiens
89 PTPN2 5771
Biochemical Activity Homo sapiens
90 DLK1  
Affinity Capture-MS Homo sapiens
91 SIRT1  
Proximity Label-MS Homo sapiens
92 TRIP11 9321
Proximity Label-MS Homo sapiens
93 ANKRD26 22852
Proximity Label-MS Homo sapiens
94 RAB11FIP1 80223
Proximity Label-MS Homo sapiens
95 RAB2A 5862
Proximity Label-MS Homo sapiens
96 PHACTR4 65979
Proximity Label-MS Homo sapiens
97 GOLGA5 9950
Proximity Label-MS Homo sapiens
98 HBEGF 1839
Affinity Capture-MS Homo sapiens
99 RAB11A 8766
Proximity Label-MS Homo sapiens
100 PLEKHA7 144100
Proximity Label-MS Homo sapiens
101 EPHA2 1969
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
102 SNW1 22938
Two-hybrid Homo sapiens
103 RAB5C 5878
Proximity Label-MS Homo sapiens
104 ADGRE5 976
Affinity Capture-MS Homo sapiens
105 VANGL1 81839
Proximity Label-MS Homo sapiens
106 UNC13B 10497
Proximity Label-MS Homo sapiens
107 CTNND1 1500
Proximity Label-MS Homo sapiens
108 SRPRB 58477
Affinity Capture-MS Homo sapiens
109 USP6NL 9712
Proximity Label-MS Homo sapiens
110 CCSER2 54462
Proximity Label-MS Homo sapiens
111 NDRG1 10397
Proximity Label-MS Homo sapiens
112 CHRNA4  
Affinity Capture-MS Homo sapiens
113 ARHGAP39  
Proximity Label-MS Homo sapiens
114 Tjp1  
Reconstituted Complex Mus musculus
115 LAMP3  
Proximity Label-MS Homo sapiens
116 NOS1AP  
Proximity Label-MS Homo sapiens
117 GJA1 2697
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
118 C1orf198 84886
Proximity Label-MS Homo sapiens
119 APC  
Proximity Label-MS Homo sapiens
120 NUMBL 9253
Proximity Label-MS Homo sapiens
121 PACSIN2 11252
Proximity Label-MS Homo sapiens
122 DTNA  
Proximity Label-MS Homo sapiens
123 ARF3 377
Proximity Label-MS Homo sapiens
124 PHLDB1 23187
Proximity Label-MS Homo sapiens
125 FMN2  
Proximity Label-MS Homo sapiens
126 VAMP2 6844
Proximity Label-MS Homo sapiens
127 IFNGR1 3459
Proximity Label-MS Homo sapiens
128 FFAR1  
Affinity Capture-MS Homo sapiens
129 TGFBR1 7046
Affinity Capture-Western Homo sapiens
Affinity Capture-Luminescence Homo sapiens
130 VANGL2  
Proximity Label-MS Homo sapiens
131 CTLA4  
Affinity Capture-MS Homo sapiens
132 ADAM9 8754
Affinity Capture-MS Homo sapiens
133 TNIK 23043
Proximity Label-MS Homo sapiens
134 MAP4K5 11183
Proximity Label-MS Homo sapiens
135 TMEM182  
Affinity Capture-MS Homo sapiens
136 PCNXL3 399909
Proximity Label-MS Homo sapiens
137 STEAP3 55240
Proximity Label-MS Homo sapiens
138 PTPN14 5784
Proximity Label-MS Homo sapiens
139 PALM 5064
Proximity Label-MS Homo sapiens
140 EBAG9 9166
Proximity Label-MS Homo sapiens
141 LMAN1 3998
Proximity Label-MS Homo sapiens
142 GOPC 57120
Proximity Label-MS Homo sapiens
143 STAM2 10254
Proximity Label-MS Homo sapiens
144 SDK2 54549
Proximity Label-MS Homo sapiens
145 SLC1A5 6510
Proximity Label-MS Homo sapiens
146 FBLN1 2192
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 RAI14 26064
Proximity Label-MS Homo sapiens
148 C2CD4C  
Proximity Label-MS Homo sapiens
149 NHS 4810
Proximity Label-MS Homo sapiens
150 LYN 4067
Proximity Label-MS Homo sapiens
151 ADD2 119
Proximity Label-MS Homo sapiens
152 SIPA1L2  
Proximity Label-MS Homo sapiens
153 TRPM7 54822
Proximity Label-MS Homo sapiens
154 LAMP1 3916
Proximity Label-MS Homo sapiens
155 JAG2  
Proximity Label-MS Homo sapiens
156 PREB 10113
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 FAM171A1 221061
Proximity Label-MS Homo sapiens
158 DNAJC5B  
Proximity Label-MS Homo sapiens
159 TMX1 81542
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 MINK1 50488
Proximity Label-MS Homo sapiens
161 MARVELD2 153562
Proximity Label-MS Homo sapiens
162 SLC19A1 6573
Proximity Label-MS Homo sapiens
163 RAB5A 5868
Proximity Label-MS Homo sapiens
164 TMPRSS11B 132724
Affinity Capture-MS Homo sapiens
165 TNFSF8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 ADCY9 115
Proximity Label-MS Homo sapiens
167 CDC42EP1 11135
Proximity Label-MS Homo sapiens
168 TJP1 7082
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
169 DAB2IP 153090
Proximity Label-MS Homo sapiens
170 RICTOR 253260
Proximity Label-MS Homo sapiens
171 USP54 159195
Proximity Label-MS Homo sapiens
172 EGFR 1956
Proximity Label-MS Homo sapiens
173 AQP3  
Affinity Capture-MS Homo sapiens
174 CDC42EP4  
Proximity Label-MS Homo sapiens
175 SPTBN1 6711
Proximity Label-MS Homo sapiens
176 GAB1  
Proximity Label-MS Homo sapiens
177 PLEKHA5 54477
Proximity Label-MS Homo sapiens
178 C4A 720
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
179 PCDH7 5099
Proximity Label-MS Homo sapiens
180 SLC3A2 6520
Proximity Label-MS Homo sapiens
181 PKP4 8502
Proximity Label-MS Homo sapiens
182 PLA2G16 11145
Affinity Capture-MS Homo sapiens
183 SLC6A15 55117
Proximity Label-MS Homo sapiens
184 ACAD9 28976
Affinity Capture-MS Homo sapiens
185 ZFYVE9  
Proximity Label-MS Homo sapiens
186 RHOB 388
Proximity Label-MS Homo sapiens
187 CCDC88A 55704
Proximity Label-MS Homo sapiens
188 CPNE8 144402
Proximity Label-MS Homo sapiens
189 GPRIN1 114787
Proximity Label-MS Homo sapiens
190 MARK3 4140
Proximity Label-MS Homo sapiens
191 RNF43  
Proximity Label-MS Homo sapiens
192 TMEM51 55092
Proximity Label-MS Homo sapiens
193 UHRF1BP1L 23074
Proximity Label-MS Homo sapiens
194 SLC38A2 54407
Proximity Label-MS Homo sapiens
195 EXOC3 11336
Proximity Label-MS Homo sapiens
196 EZR 7430
Proximity Label-MS Homo sapiens
197 SIPA1L3  
Proximity Label-MS Homo sapiens
198 SLAMF1 6504
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 ERGIC2 51290
Proximity Label-MS Homo sapiens
200 BSG 682
Proximity Label-MS Homo sapiens
201 KIAA0754  
Proximity Label-MS Homo sapiens
202 ATP1A1 476
Proximity Label-MS Homo sapiens
203 YKT6 10652
Proximity Label-MS Homo sapiens
204 IGF2R 3482
Proximity Label-MS Homo sapiens
205 FLOT1 10211
Proximity Label-MS Homo sapiens
206 RPS6KC1  
Proximity Label-MS Homo sapiens
207 ANK3  
Proximity Label-MS Homo sapiens
208 ARAP2  
Proximity Label-MS Homo sapiens
209 MAGI1  
Proximity Label-MS Homo sapiens
210 VPS8 23355
Proximity Label-MS Homo sapiens
211 CC2D1A 54862
Proximity Label-MS Homo sapiens
212 PTPRG 5793
Proximity Label-MS Homo sapiens
213 CCSER1  
Proximity Label-MS Homo sapiens
214 DLG5 9231
Proximity Label-MS Homo sapiens
215 ZDHHC5 25921
Proximity Label-MS Homo sapiens
216 ANK2 287
Proximity Label-MS Homo sapiens
217 MARCKS 4082
Proximity Label-MS Homo sapiens
218 WASF2 10163
Proximity Label-MS Homo sapiens
219 EFR3A 23167
Proximity Label-MS Homo sapiens
220 PARD3 56288
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
221 EPB41L3 23136
Proximity Label-MS Homo sapiens
222 EPB41L5 57669
Proximity Label-MS Homo sapiens
223 ADGRL2 23266
Proximity Label-MS Homo sapiens
224 MFAP4 4239
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
225 ROBO1 6091
Proximity Label-MS Homo sapiens
226 SHB 6461
Proximity Label-MS Homo sapiens
227 APBB1  
Proximity Label-MS Homo sapiens
228 STX4 6810
Proximity Label-MS Homo sapiens
229 CLEC7A  
Two-hybrid Homo sapiens
230 PI4KA 5297
Proximity Label-MS Homo sapiens
231 VRK2 7444
Proximity Label-MS Homo sapiens
232 RDX 5962
Proximity Label-MS Homo sapiens
233 MLLT4 4301
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
234 PAK4 10298
Proximity Label-MS Homo sapiens
235 FAM171A2 284069
Proximity Label-MS Homo sapiens
236 IGSF8 93185
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
237 RASAL2 9462
Proximity Label-MS Homo sapiens
238 RAB3B 5865
Proximity Label-MS Homo sapiens
239 DSC2 1824
Proximity Label-MS Homo sapiens
240 PCNX  
Proximity Label-MS Homo sapiens
241 PHLDB2 90102
Proximity Label-MS Homo sapiens
242 EFEMP1 2202
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
243 TNFSF9  
Affinity Capture-MS Homo sapiens
244 NDUFAF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
245 RAB8B 51762
Affinity Capture-Western Homo sapiens
246 SNAP23 8773
Proximity Label-MS Homo sapiens
247 ESYT2 57488
Proximity Label-MS Homo sapiens
248 CTAGE5 4253
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
249 METTL7A 25840
Proximity Label-MS Homo sapiens
250 PLEKHA1 59338
Proximity Label-MS Homo sapiens
251 SLC30A1 7779
Proximity Label-MS Homo sapiens
252 NF2 4771
Proximity Label-MS Homo sapiens
253 IRS4 8471
Proximity Label-MS Homo sapiens
254 ANTXR1 84168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
255 CXADR 1525
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
256 SIPA1L1 26037
Proximity Label-MS Homo sapiens
257 SNX5 27131
Proximity Label-MS Homo sapiens
258 RAB4A 5867
Proximity Label-MS Homo sapiens
259 DNAJC5 80331
Proximity Label-MS Homo sapiens
260 NUMB 8650
Proximity Label-MS Homo sapiens
261 DIRAS3  
Proximity Label-MS Homo sapiens
262 KIAA1522 57648
Proximity Label-MS Homo sapiens
263 RPN1 6184
Proximity Label-MS Homo sapiens
264 PIK3R1 5295
Proximity Label-MS Homo sapiens
265 ARHGEF12 23365
Proximity Label-MS Homo sapiens
266 ARL13B 200894
Proximity Label-MS Homo sapiens
267 SCN3B  
Affinity Capture-MS Homo sapiens
268 SLC4A7 9497
Proximity Label-MS Homo sapiens
269 OGT 8473
Reconstituted Complex Homo sapiens
270 KIAA1462 57608
Proximity Label-MS Homo sapiens
271 OCRL 4952
Proximity Label-MS Homo sapiens
272 FERMT2 10979
Proximity Label-MS Homo sapiens
273 VAMP3 9341
Proximity Label-MS Homo sapiens
274 CLEC4A  
Affinity Capture-MS Homo sapiens
275 SYDE1 85360
Proximity Label-MS Homo sapiens
276 KIF26B  
Proximity Label-MS Homo sapiens
277 TBC1D8  
Proximity Label-MS Homo sapiens
278 CDC42BPA 8476
Proximity Label-MS Homo sapiens
279 MICB  
Affinity Capture-MS Homo sapiens
280 MYO1D 4642
Proximity Label-MS Homo sapiens
281 PCDH10 57575
Affinity Capture-MS Homo sapiens
282 PTPN13 5783
Proximity Label-MS Homo sapiens
283 RAB9A 9367
Proximity Label-MS Homo sapiens
284 EPB41 2035
Proximity Label-MS Homo sapiens
285 SH3D19 152503
Proximity Label-MS Homo sapiens
286 CGN  
Proximity Label-MS Homo sapiens
287 KIAA1671  
Proximity Label-MS Homo sapiens
288 ZC3HAV1 56829
Proximity Label-MS Homo sapiens
289 SEPT7 989
Proximity Label-MS Homo sapiens
290 SLC22A4 6583
Affinity Capture-MS Homo sapiens
291 HLA-A 3105
Proximity Label-MS Homo sapiens
292 ATP7A 538
Proximity Label-MS Homo sapiens
293 CASKIN2  
Proximity Label-MS Homo sapiens
294 NEDD4L 23327
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
295 DEPDC1B 55789
Proximity Label-MS Homo sapiens
296 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
297 PVRL2 5819
Proximity Label-MS Homo sapiens
298 EPB41L4B 54566
Proximity Label-MS Homo sapiens
299 ITSN1 6453
Proximity Label-MS Homo sapiens
300 JUP 3728
Proximity Label-MS Homo sapiens
301 LDLRAD1  
Affinity Capture-MS Homo sapiens
302 FAM171B  
Proximity Label-MS Homo sapiens
303 LSR 51599
Proximity Label-MS Homo sapiens
304 EPHA4 2043
Proximity Label-MS Homo sapiens
305 EFNB1 1947
Proximity Label-MS Homo sapiens
306 INSR 3643
Proximity Label-MS Homo sapiens
307 ERGIC1 57222
Proximity Label-MS Homo sapiens
308 C11orf52 91894
Proximity Label-MS Homo sapiens
309 PLK1 5347
Proximity Label-MS Homo sapiens
310 PPP1R9A  
Proximity Label-MS Homo sapiens
311 PPP1R13B  
Proximity Label-MS Homo sapiens
312 MARK2 2011
Proximity Label-MS Homo sapiens
313 FRS2 10818
Proximity Label-MS Homo sapiens
314 RAB7A 7879
Proximity Label-MS Homo sapiens
315 ROBO2 6092
Proximity Label-MS Homo sapiens
316 KANK2 25959
Proximity Label-MS Homo sapiens
317 TULP3 7289
Proximity Label-MS Homo sapiens
318 XPR1 9213
Proximity Label-MS Homo sapiens
319 SYT12  
Affinity Capture-MS Homo sapiens
320 CAV1 857
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
321 NOTCH1 4851
Proximity Label-MS Homo sapiens
322 ABLIM1 3983
Proximity Label-MS Homo sapiens
323 ILDR2  
Proximity Label-MS Homo sapiens
324 TNFAIP3 7128
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
325 RAMP3  
Affinity Capture-MS Homo sapiens
326 ARHGAP21 57584
Proximity Label-MS Homo sapiens
327 SPTAN1 6709
Proximity Label-MS Homo sapiens
328 AP2B1 163
Proximity Label-MS Homo sapiens
329 CDC42BPB 9578
Proximity Label-MS Homo sapiens
330 CEP89 84902
Proximity Label-MS Homo sapiens
331 AKAP12 9590
Proximity Label-MS Homo sapiens
332 FPR1  
Affinity Capture-MS Homo sapiens
333 LAMP2 3920
Proximity Label-MS Homo sapiens
334 BASP1 10409
Proximity Label-MS Homo sapiens
335 LNPEP 4012
Proximity Label-MS Homo sapiens
336 PRR5  
Proximity Label-MS Homo sapiens
337 SNX6 58533
Proximity Label-MS Homo sapiens
338 SLC12A2 6558
Proximity Label-MS Homo sapiens
339 USP31 57478
Proximity Label-MS Homo sapiens
340 B3GAT1  
Proximity Label-MS Homo sapiens
341 SLC39A14 23516
Proximity Label-MS Homo sapiens
342 SLC39A10 57181
Proximity Label-MS Homo sapiens
343 FAM83B  
Proximity Label-MS Homo sapiens
344 SCRIB 23513
Proximity Label-MS Homo sapiens
345 YES1 7525
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
346 CPD 1362
Proximity Label-MS Homo sapiens
347 HGS 9146
Affinity Capture-Western Homo sapiens
348 ADD1 118
Proximity Label-MS Homo sapiens
349 TIAM1  
Proximity Label-MS Homo sapiens
350 SEMA4C 54910
Proximity Label-MS Homo sapiens
351 FAM135A  
Proximity Label-MS Homo sapiens
352 PEAK1 79834
Proximity Label-MS Homo sapiens
353 INADL 10207
Proximity Label-MS Homo sapiens
354 RAB35 11021
Proximity Label-MS Homo sapiens
355 ERBB2 2064
Proximity Label-MS Homo sapiens
356 TMEM2 23670
Proximity Label-MS Homo sapiens
357 NEDD4 4734
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
358 LAMTOR1 55004
Proximity Label-MS Homo sapiens
359 CASK 8573
Proximity Label-MS Homo sapiens
360 COBLL1 22837
Proximity Label-MS Homo sapiens
361 AGFG1 3267
Proximity Label-MS Homo sapiens
362 DLGAP4 22839
Proximity Label-MS Homo sapiens
363 EMP3 2014
Affinity Capture-MS Homo sapiens
364 TNKS1BP1 85456
Proximity Label-MS Homo sapiens
365 SCAMP1 9522
Proximity Label-MS Homo sapiens
366 CNNM3 26505
Proximity Label-MS Homo sapiens
367 C19orf26 255057
Proximity Label-MS Homo sapiens
368 CCDC85C  
Proximity Label-MS Homo sapiens
369 MYO1B 4430
Proximity Label-MS Homo sapiens
370 MIA3 375056
Affinity Capture-MS Homo sapiens
371 SLC7A2 6542
Proximity Label-MS Homo sapiens
372 STX6 10228
Proximity Label-MS Homo sapiens
373 ULK1  
Two-hybrid Homo sapiens
374 ATP2B4 493
Proximity Label-MS Homo sapiens
375 TBC1D10B 26000
Proximity Label-MS Homo sapiens
376 ITCH 83737
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Proximity Label-MS Homo sapiens
377 ELOVL5 60481
Proximity Label-MS Homo sapiens
378 ACBD3 64746
Proximity Label-MS Homo sapiens
379 SNAP29 9342
Proximity Label-MS Homo sapiens
380 CACHD1  
Proximity Label-MS Homo sapiens
381 RALGAPA1 253959
Proximity Label-MS Homo sapiens
382 GOLGA3 2802
Proximity Label-MS Homo sapiens
383 ROR1 4919
Proximity Label-MS Homo sapiens
384 SDC1 6382
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
385 PANX1 24145
Proximity Label-MS Homo sapiens
386 SLC39A6 25800
Proximity Label-MS Homo sapiens
387 ATP2B1 490
Proximity Label-MS Homo sapiens
388 EPB41L4A 64097
Proximity Label-MS Homo sapiens
389 CTNNB1 1499
Proximity Label-MS Homo sapiens
390 SLC30A6 55676
Proximity Label-MS Homo sapiens
391 TRIO 7204
Proximity Label-MS Homo sapiens
392 SLC7A5 8140
Proximity Label-MS Homo sapiens
393 ARF6 382
Proximity Label-MS Homo sapiens
394 UACA 55075
Proximity Label-MS Homo sapiens
395 EHBP1 23301
Proximity Label-MS Homo sapiens
396 LZTS2 84445
Proximity Label-MS Homo sapiens
397 PRKACA 5566
Proximity Label-MS Homo sapiens
398 KIRREL 55243
Proximity Label-MS Homo sapiens
399 FCHO2 115548
Proximity Label-MS Homo sapiens
400 AKAP5  
Proximity Label-MS Homo sapiens
401 EPN1 29924
Affinity Capture-Western Homo sapiens
402 PPFIBP1 8496
Proximity Label-MS Homo sapiens
403 KRAS 3845
Proximity Label-MS Homo sapiens
404 FATE1  
Two-hybrid Homo sapiens
405 PPFIA1 8500
Proximity Label-MS Homo sapiens
406 FARP1 10160
Proximity Label-MS Homo sapiens
407 CCDC8  
Proximity Label-MS Homo sapiens
408 DNAJC13 23317
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
409 SEC24B 10427
Proximity Label-MS Homo sapiens
410 KIAA1549  
Proximity Label-MS Homo sapiens
411 ANKFY1 51479
Proximity Label-MS Homo sapiens
412 MFSD4  
Affinity Capture-MS Homo sapiens
413 UBA52 7311
Proximity Label-MS Homo sapiens
414 TMEM30B 161291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
415 NISCH 11188
Proximity Label-MS Homo sapiens
416 EPB41L2 2037
Proximity Label-MS Homo sapiens
417 ROR2 4920
Proximity Label-MS Homo sapiens
418 SLC25A4 291
Proximity Label-MS Homo sapiens
419 MICAL3 57553
Proximity Label-MS Homo sapiens
420 SLC38A1 81539
Proximity Label-MS Homo sapiens
421 SLC6A8 6535
Proximity Label-MS Homo sapiens
422 PIK3R2 5296
Proximity Label-MS Homo sapiens
423 RAPGEF6 51735
Proximity Label-MS Homo sapiens
424 UBIAD1 29914
Proximity Label-MS Homo sapiens
425 DSG2 1829
Proximity Label-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here