Gene description for ADAMTS12
Gene name	ADAM metallopeptidase with thrombospondin type 1 motif, 12
Gene symbol	ADAMTS12
Other names/aliases	PRO4389
Species	Homo sapiens
Database cross references - ADAMTS12
ExoCarta	ExoCarta_81792
Entrez Gene	81792
HGNC	14605
MIM	606184
UniProt	P58397
ADAMTS12 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for ADAMTS12

Molecular Function     zinc ion binding GO:0008270 IEA     metalloendopeptidase activity GO:0004222 IDA     protein binding GO:0005515 IPI Biological Process     negative regulation of cellular response to vascular endothelial growth factor stimulus GO:1902548 IDA     cellular response to BMP stimulus GO:0071773 IDA     regulation of inflammatory response GO:0050727 IDA     proteoglycan catabolic process GO:0030167 IDA     cell migration GO:0016477 IMP     negative regulation of chondrocyte differentiation GO:0032331 IDA     regulation of endothelial tube morphogenesis GO:1901509 IDA     negative regulation of hepatocyte growth factor receptor signaling pathway GO:1902203 IDA     negative regulation of cellular response to hepatocyte growth factor stimulus GO:2001113 IDA     cellular response to tumor necrosis factor GO:0071356 IMP     cell-matrix adhesion GO:0007160 IMP     cellular response to interleukin-1 GO:0071347 IMP     proteolysis involved in cellular protein catabolic process GO:0051603 IMP Subcellular Localization     proteinaceous extracellular matrix GO:0005578 IEA     extracellular matrix GO:0031012 IDA