Gene description for SHANK2
Gene name	SH3 and multiple ankyrin repeat domains 2
Gene symbol	SHANK2
Other names/aliases	AUTS17 CORTBP1 CTTNBP1 ProSAP1 SHANK SPANK-3
Species	Homo sapiens
Database cross references - SHANK2
ExoCarta	ExoCarta_22941
Vesiclepedia	VP_22941
Entrez Gene	22941
HGNC	14295
MIM	603290
UniProt	Q9UPX8
SHANK2 identified in exosomes derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for SHANK2

Molecular Function     protein binding GO:0005515 IPI     SH3 domain binding GO:0017124 IEA     synaptic receptor adaptor activity GO:0030160 IBA     synaptic receptor adaptor activity GO:0030160 NAS     ionotropic glutamate receptor binding GO:0035255 IBA     ionotropic glutamate receptor binding GO:0035255 ISS     structural constituent of postsynaptic density GO:0098919 IEA Biological Process     synapse assembly GO:0007416 ISS     response to nutrient GO:0007584 IEA     learning GO:0007612 IMP     positive regulation of cell population proliferation GO:0008284 IMP     associative learning GO:0008306 IEA     adult locomotory behavior GO:0008344 IEA     response to xenobiotic stimulus GO:0009410 IEA     adult behavior GO:0030534 IMP     social behavior GO:0035176 IMP     negative regulation of hippo signaling GO:0035331 IMP     long-term synaptic potentiation GO:0060291 ISS     long-term synaptic depression GO:0060292 ISS     vocalization behavior GO:0071625 IMP     regulation of postsynapse organization GO:0099175 IEA     maintenance of postsynaptic density structure GO:0099562 IEA Subcellular Localization     photoreceptor outer segment GO:0001750 ISS     photoreceptor inner segment GO:0001917 ISS     cytosol GO:0005829 TAS     neurofilament GO:0005883 ISS     plasma membrane GO:0005886 ISS     postsynaptic density GO:0014069 IBA     postsynaptic density GO:0014069 ISS     apical plasma membrane GO:0016324 ISS     growth cone GO:0030426 ISS     brush border membrane GO:0031526 ISS     neuron projection GO:0043005 ISS     neuronal cell body GO:0043025 ISS     dendritic spine GO:0043197 IBA     dendritic spine GO:0043197 ISS     postsynaptic membrane GO:0045211 IBA     postsynaptic membrane GO:0045211 ISS     presynaptic active zone GO:0048786 IEA     ciliary membrane GO:0060170 ISS     hippocampal mossy fiber to CA3 synapse GO:0098686 IEA     glutamatergic synapse GO:0098978 IEA