Gene description for CMBL
Gene name carboxymethylenebutenolidase homolog (Pseudomonas)
Gene symbol CMBL
Other names/aliases JS-1
Species Homo sapiens
 Database cross references - CMBL
ExoCarta ExoCarta_134147
Entrez Gene 134147
HGNC 25090
MIM 613379
UniProt Q96DG6  
 CMBL identified in exosomes derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for CMBL
Molecular Function
    hydrolase activity GO:0016787 IEA
Biological Process
    metabolic process GO:0008152 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IDA
    cytosol GO:0005829 IEA
 Experiment description of studies that identified CMBL in exosomes
Experiment ID 63
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for CMBL
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF4A2 1974
Affinity Capture-MS Homo sapiens
2 CD2BP2 10421
Affinity Capture-MS Homo sapiens
3 ATIC 471
Affinity Capture-MS Homo sapiens
4 CUL2 8453
Affinity Capture-MS Homo sapiens
5 ARRB1 408
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CMBL is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here