Gene description for BAG6
Gene name BCL2-associated athanogene 6
Gene symbol BAG6
Other names/aliases BAG-6
BAT3
D6S52E
G3
Species Homo sapiens
 Database cross references - BAG6
ExoCarta ExoCarta_7917
Vesiclepedia VP_7917
Entrez Gene 7917
HGNC 13919
MIM 142590
UniProt P46379  
 BAG6 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
 Gene ontology annotations for BAG6
Molecular Function
    signaling receptor binding GO:0005102 IPI
    protein binding GO:0005515 IPI
    Hsp70 protein binding GO:0030544 IEA
    polyubiquitin modification-dependent protein binding GO:0031593 IBA
    polyubiquitin modification-dependent protein binding GO:0031593 ISS
    ubiquitin protein ligase binding GO:0031625 IPI
    identical protein binding GO:0042802 IPI
    ribosome binding GO:0043022 IDA
    receptor ligand activity GO:0048018 IDA
    misfolded protein binding GO:0051787 IBA
    misfolded protein binding GO:0051787 IDA
    molecular adaptor activity GO:0060090 EXP
    proteasome binding GO:0070628 ISS
    ubiquitin-specific protease binding GO:1990381 IPI
Biological Process
    kidney development GO:0001822 ISS
    immune response-activating cell surface receptor signaling pathway GO:0002429 IDA
    chromatin organization GO:0006325 IEA
    ubiquitin-dependent protein catabolic process GO:0006511 IDA
    ubiquitin-dependent protein catabolic process GO:0006511 ISS
    post-translational protein targeting to endoplasmic reticulum membrane GO:0006620 IDA
    apoptotic process GO:0006915 IDA
    synaptonemal complex assembly GO:0007130 ISS
    spermatogenesis GO:0007283 ISS
    brain development GO:0007420 ISS
    proteasomal protein catabolic process GO:0010498 IMP
    internal peptidyl-lysine acetylation GO:0018393 IDA
    natural killer cell activation GO:0030101 IDA
    cell differentiation GO:0030154 IEA
    lung development GO:0030324 ISS
    regulation of protein stability GO:0031647 IDA
    negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435 ISS
    ERAD pathway GO:0036503 IBA
    ERAD pathway GO:0036503 IDA
    ERAD pathway GO:0036503 IMP
    ERAD pathway GO:0036503 NAS
    maintenance of unfolded protein GO:0036506 IMP
    intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 IMP
    negative regulation of apoptotic process GO:0043066 IEA
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IEA
    negative regulation of proteolysis GO:0045861 ISS
    regulation of embryonic development GO:0045995 ISS
    protein stabilization GO:0050821 ISS
    NK T cell activation GO:0051132 IDA
    endoplasmic reticulum stress-induced pre-emptive quality control GO:0061857 IMP
    intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 ISS
    tail-anchored membrane protein insertion into ER membrane GO:0071816 IDA
    positive regulation of ERAD pathway GO:1904294 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 NAS
    membrane GO:0016020 HDA
    membrane GO:0016020 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
    extracellular exosome GO:0070062 IDA
    BAT3 complex GO:0071818 IBA
    BAT3 complex GO:0071818 IDA
    BAT3 complex GO:0071818 IPI
 Experiment description of studies that identified BAG6 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
21
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for BAG6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 WDR91 29062
Affinity Capture-MS Homo sapiens
2 UBL4A 8266
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
3 VAPB 9217
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
4 TK1 7083
Two-hybrid Homo sapiens
5 ZFAND2B  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
6 GADD45A  
Two-hybrid Homo sapiens
7 KLC3  
Affinity Capture-MS Homo sapiens
8 MKNK2 2872
Affinity Capture-MS Homo sapiens
9 C9orf78 51759
Affinity Capture-MS Homo sapiens
10 KPNA2 3838
Reconstituted Complex Homo sapiens
11 CCNB1IP1  
Affinity Capture-MS Homo sapiens
12 PRPF40A 55660
Two-hybrid Homo sapiens
13 ATN1  
Two-hybrid Homo sapiens
14 CDK5 1020
Two-hybrid Homo sapiens
15 TRIOBP 11078
Affinity Capture-MS Homo sapiens
16 POU5F1  
Affinity Capture-MS Homo sapiens
17 IGF2 3481
Two-hybrid Homo sapiens
18 FAF1 11124
Affinity Capture-MS Homo sapiens
19 METTL23  
Affinity Capture-MS Homo sapiens
20 RNF126  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
21 ZFYVE9  
Two-hybrid Homo sapiens
22 WRAP73 49856
Affinity Capture-MS Homo sapiens
23 BAG6 7917
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
24 ENOPH1 58478
Affinity Capture-MS Homo sapiens
25 TCOF1 6949
Affinity Capture-MS Homo sapiens
26 ANXA7 310
Two-hybrid Homo sapiens
27 MTCH2 23788
Proximity Label-MS Homo sapiens
28 NOMO1 23420
Two-hybrid Homo sapiens
29 CRY1  
Affinity Capture-MS Homo sapiens
30 RAB14 51552
Affinity Capture-MS Homo sapiens
31 TRAFD1  
Affinity Capture-MS Homo sapiens
32 CLU 1191
Two-hybrid Homo sapiens
33 CSTF2 1478
Two-hybrid Homo sapiens
34 MYDGF 56005
Two-hybrid Homo sapiens
35 TRIM21 6737
Affinity Capture-MS Homo sapiens
36 ASCC2 84164
Affinity Capture-MS Homo sapiens
37 RRP1B 23076
Affinity Capture-MS Homo sapiens
38 PRKAR1B  
Two-hybrid Homo sapiens
39 SEC61B 10952
Reconstituted Complex Homo sapiens
40 UBR2 23304
Affinity Capture-MS Homo sapiens
41 PTN  
Two-hybrid Homo sapiens
42 HSPA5 3309
Affinity Capture-MS Homo sapiens
43 REG1B  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
44 AGBL4  
Affinity Capture-MS Homo sapiens
45 TARBP1 6894
Affinity Capture-MS Homo sapiens
46 ARRDC4  
Affinity Capture-MS Homo sapiens
47 ARPC3 10094
Two-hybrid Homo sapiens
48 UBQLN2 29978
Two-hybrid Homo sapiens
49 MTNR1A  
Two-hybrid Homo sapiens
50 RAD54L 8438
Affinity Capture-MS Homo sapiens
51 SDC2 6383
Two-hybrid Homo sapiens
52 FN1 2335
Affinity Capture-MS Homo sapiens
53 HEXA 3073
Affinity Capture-MS Homo sapiens
54 TUBA4A 7277
Affinity Capture-Western Homo sapiens
55 CTCFL  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
56 PTTG1  
Affinity Capture-MS Homo sapiens
57 TAC1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
58 UHRF1BP1 54887
Affinity Capture-MS Homo sapiens
59 PRMT2  
Two-hybrid Homo sapiens
60 GOLGA1  
Affinity Capture-MS Homo sapiens
61 HSPA1A 3303
Affinity Capture-Western Homo sapiens
62 SGTA 6449
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
63 SIRT5 23408
Affinity Capture-MS Homo sapiens
64 AKT1 207
Biochemical Activity Homo sapiens
65 STUB1 10273
Affinity Capture-MS Homo sapiens
66 PSMB2 5690
Affinity Capture-MS Homo sapiens
67 YBX1 4904
Affinity Capture-MS Homo sapiens
68 SRGN 5552
Two-hybrid Homo sapiens
69 FASN 2194
Negative Genetic Homo sapiens
70 CTSL 1514
Two-hybrid Homo sapiens
71 NBL1 4681
Two-hybrid Homo sapiens
72 POLR2J  
Two-hybrid Homo sapiens
73 CDK8 1024
Affinity Capture-MS Homo sapiens
74 FUZ 80199
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
75 MACF1 23499
Affinity Capture-MS Homo sapiens
76 USP1 7398
Affinity Capture-MS Homo sapiens
77 MTA1 9112
Affinity Capture-MS Homo sapiens
78 UBL4B  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
79 CDSN 1041
Two-hybrid Homo sapiens
80 NCR3  
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
81 DYNC1H1 1778
Affinity Capture-MS Homo sapiens
82 CNTRL  
Affinity Capture-MS Homo sapiens
83 PHKA2 5256
Affinity Capture-MS Homo sapiens
84 WWP2 11060
Affinity Capture-MS Homo sapiens
85 TSC22D1 8848
Affinity Capture-MS Homo sapiens
86 CDK4 1019
Two-hybrid Homo sapiens
87 RAB11A 8766
Affinity Capture-MS Homo sapiens
88 LDLR 3949
Negative Genetic Homo sapiens
89 TXNIP 10628
Affinity Capture-MS Homo sapiens
90 CUL7 9820
Affinity Capture-MS Homo sapiens
91 MRPL55  
Affinity Capture-MS Homo sapiens
92 RNF5  
Affinity Capture-MS Homo sapiens
93 PSMC4 5704
Affinity Capture-MS Homo sapiens
94 FKBP2 2286
Two-hybrid Homo sapiens
95 SEC61A1 29927
Reconstituted Complex Homo sapiens
96 CDCA5  
Affinity Capture-MS Homo sapiens
97 LCK 3932
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
98 ZNF286A  
Affinity Capture-MS Homo sapiens
99 USP13  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
100 FZD4 8322
Two-hybrid Homo sapiens
101 TARDBP 23435
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
102 SRSF2 6427
Affinity Capture-MS Homo sapiens
103 TTR 7276
Two-hybrid Homo sapiens
104 TSEN2  
Affinity Capture-MS Homo sapiens
105 TRA  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
106 ATM 472
Affinity Capture-MS Homo sapiens
107 VAMP2 6844
Reconstituted Complex Homo sapiens
108 SYVN1 84447
Affinity Capture-Western Homo sapiens
109 SETDB1  
Two-hybrid Homo sapiens
110 UAP1 6675
Affinity Capture-MS Homo sapiens
111 VPS26A 9559
Affinity Capture-MS Homo sapiens
112 S100A4 6275
Two-hybrid Homo sapiens
113 FIS1 51024
Proximity Label-MS Homo sapiens
114 HSPA2 3306
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
115 TLN1 7094
Affinity Capture-MS Homo sapiens
116 WDR83  
Affinity Capture-MS Homo sapiens
117 FANCD2  
Affinity Capture-MS Homo sapiens
118 AIFM1 9131
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
119 VCAM1 7412
Affinity Capture-Western Homo sapiens
120 SHFM1 7979
Affinity Capture-MS Homo sapiens
121 GSK3B 2932
Two-hybrid Homo sapiens
122 PRNP 5621
Two-hybrid Homo sapiens
123 ATXN2 6311
Two-hybrid Homo sapiens
124 MAPK3 5595
Affinity Capture-MS Homo sapiens
125 CEP55 55165
Affinity Capture-MS Homo sapiens
126 CDKN1A  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
127 PALMD  
Affinity Capture-MS Homo sapiens
128 AMFR 267
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
129 NHS 4810
Affinity Capture-MS Homo sapiens
130 PSMD14 10213
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
131 RNF115  
Co-purification Homo sapiens
132 POLR3F  
Affinity Capture-MS Homo sapiens
133 TBC1D32 221322
Proximity Label-MS Homo sapiens
134 UBR5 51366
Affinity Capture-MS Homo sapiens
135 ARRDC2  
Affinity Capture-MS Homo sapiens
136 CDKN3 1033
Affinity Capture-MS Homo sapiens
137 PLK1 5347
Two-hybrid Homo sapiens
138 TRIP10 9322
Affinity Capture-MS Homo sapiens
139 IL17RC 84818
Affinity Capture-MS Homo sapiens
140 STX5 6811
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
141 ICAM5 7087
Affinity Capture-MS Homo sapiens
142 GET4 51608
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
143 DPT  
Two-hybrid Homo sapiens
144 HNRNPD 3184
Affinity Capture-MS Homo sapiens
145 FURIN 5045
Affinity Capture-MS Homo sapiens
146 SMEK2  
Affinity Capture-MS Homo sapiens
147 USP15 9958
Affinity Capture-MS Homo sapiens
148 REEP3 221035
Affinity Capture-MS Homo sapiens
149 RIPK4  
Affinity Capture-MS Homo sapiens
150 SGTB  
Affinity Capture-MS Homo sapiens
151 CEBPZ  
Affinity Capture-MS Homo sapiens
152 BLMH 642
Affinity Capture-MS Homo sapiens
153 CSNK2B 1460
Two-hybrid Homo sapiens
154 RCN2 5955
Two-hybrid Homo sapiens
155 Zbtb7a  
Affinity Capture-MS Mus musculus
156 CCDC88A 55704
Affinity Capture-MS Homo sapiens
157 SERPING1 710
Two-hybrid Homo sapiens
158 PASK  
Affinity Capture-MS Homo sapiens
159 TOMM20 9804
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
160 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
161 EIF3H 8667
Affinity Capture-MS Homo sapiens
162 ZRANB1 54764
Affinity Capture-MS Homo sapiens
163 KIF21B 23046
Affinity Capture-MS Homo sapiens
164 ICK  
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
165 CEP170P1  
Affinity Capture-MS Homo sapiens
166 AMTN  
Two-hybrid Homo sapiens
167 FAF2 23197
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
168 MEST 4232
Two-hybrid Homo sapiens
169 PDCL 5082
Affinity Capture-MS Homo sapiens
170 SPP1 6696
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
171 CALU 813
Affinity Capture-MS Homo sapiens
172 CTAG1B  
Two-hybrid Homo sapiens
173 MCL1 4170
Co-fractionation Homo sapiens
174 PPIL3 53938
Affinity Capture-MS Homo sapiens
175 OTUB1 55611
Affinity Capture-MS Homo sapiens
176 RAB8A 4218
Two-hybrid Homo sapiens
177 EEF1D 1936
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
178 C16orf72 29035
Affinity Capture-MS Homo sapiens
179 B2M 567
Two-hybrid Homo sapiens
180 C2CD5 9847
Affinity Capture-MS Homo sapiens
181 EP300 2033
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
182 KLHL12  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
183 EFEMP2 30008
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
184 FAM58A  
Affinity Capture-MS Homo sapiens
185 PTMA 5757
Affinity Capture-MS Homo sapiens
186 MRPL17  
Affinity Capture-MS Homo sapiens
187 MYEOV  
Affinity Capture-MS Homo sapiens
188 DNAJA4 55466
Affinity Capture-MS Homo sapiens
189 FAM9B  
Two-hybrid Homo sapiens
190 TRIM27  
Affinity Capture-MS Homo sapiens
191 FAM46A  
Two-hybrid Homo sapiens
192 RET 5979
Affinity Capture-MS Homo sapiens
193 PEBP1 5037
Co-fractionation Homo sapiens
194 PI4KA 5297
Affinity Capture-MS Homo sapiens
195 RHO  
Affinity Capture-Western Bos taurus
Affinity Capture-Western Bos taurus
196 IGFBP5 3488
Two-hybrid Homo sapiens
197 ACTR8 93973
Affinity Capture-MS Homo sapiens
198 FAM173A  
Two-hybrid Homo sapiens
199 PTPN12 5782
Two-hybrid Homo sapiens
200 CHMP5 51510
Affinity Capture-MS Homo sapiens
201 PTH  
Two-hybrid Homo sapiens
202 EFEMP1 2202
Two-hybrid Homo sapiens
203 RCC1 1104
Two-hybrid Homo sapiens
204 WDFY3 23001
Affinity Capture-MS Homo sapiens
205 MAVS 57506
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
206 TFCP2 7024
Two-hybrid Homo sapiens
207 UBQLN4 56893
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
208 FAS 355
Two-hybrid Homo sapiens
209 INSIG2  
Affinity Capture-MS Homo sapiens
210 GOLGA6L9  
Two-hybrid Homo sapiens
211 SAMM50 25813
Proximity Label-MS Homo sapiens
212 ANTXR1 84168
Affinity Capture-MS Homo sapiens
213 SBF2 81846
Affinity Capture-MS Homo sapiens
214 IQCG 84223
Two-hybrid Homo sapiens
215 GTF2IRD1  
Affinity Capture-MS Homo sapiens
216 XRN1 54464
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
217 DOT1L 84444
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
218 CAST 831
Affinity Capture-MS Homo sapiens
219 NOP2 4839
Affinity Capture-MS Homo sapiens
220 ASNA1 439
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Co-purification Homo sapiens
221 DNAJC5 80331
Proximity Label-MS Homo sapiens
222 MAPT  
Affinity Capture-MS Homo sapiens
223 CNOT1 23019
Affinity Capture-MS Homo sapiens
224 NTRK1 4914
Affinity Capture-MS Homo sapiens
225 NPY  
Two-hybrid Homo sapiens
226 CTSB 1508
Two-hybrid Homo sapiens
227 DNAJC5G  
Proximity Label-MS Homo sapiens
228 PLXNA3 55558
Affinity Capture-MS Homo sapiens
229 PELP1 27043
Two-hybrid Homo sapiens
230 CTSE  
Two-hybrid Homo sapiens
231 ZBTB2 57621
Affinity Capture-MS Homo sapiens
232 PPAP2C 8612
Two-hybrid Homo sapiens
233 DNAJB12 54788
Proximity Label-MS Homo sapiens
234 OSBPL2 9885
Affinity Capture-MS Homo sapiens
235 C1QA 712
Two-hybrid Homo sapiens
236 TRIM11  
Affinity Capture-MS Homo sapiens
237 METTL21B  
Affinity Capture-MS Homo sapiens
238 PDCD11 22984
Affinity Capture-MS Homo sapiens
239 LAMTOR5 10542
Affinity Capture-MS Homo sapiens
240 MTOR 2475
Affinity Capture-MS Homo sapiens
241 TP63  
Two-hybrid Homo sapiens
242 IP6K3  
Affinity Capture-MS Homo sapiens
243 ITGB4 3691
Affinity Capture-MS Homo sapiens
244 HLA-A 3105
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
245 PWP2 5822
Affinity Capture-MS Homo sapiens
246 AKAP1 8165
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
247 IMMT 10989
Two-hybrid Homo sapiens
248 LLGL2 3993
Affinity Capture-MS Homo sapiens
249 KIF2A 3796
Affinity Capture-MS Homo sapiens
250 CXCL8 3576
Two-hybrid Homo sapiens
251 SMN1 6606
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
252 FBXL6  
Affinity Capture-MS Homo sapiens
253 ERLIN1 10613
Affinity Capture-MS Homo sapiens
254 PIN1 5300
Two-hybrid Homo sapiens
255 FANCL 55120
Affinity Capture-MS Homo sapiens
256 TUBB3 10381
Affinity Capture-MS Homo sapiens
257 URB1 9875
Affinity Capture-MS Homo sapiens
258 ERLIN2 11160
Affinity Capture-MS Homo sapiens
259 UBR3  
Affinity Capture-MS Homo sapiens
260 RAVER1 125950
Affinity Capture-MS Homo sapiens
261 PNPLA8 50640
Affinity Capture-MS Homo sapiens
262 RAB7A 7879
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
263 METTL3  
Affinity Capture-MS Homo sapiens
264 STK11 6794
Negative Genetic Homo sapiens
265 AR 367
Affinity Capture-MS Homo sapiens
266 RAC1 5879
Two-hybrid Homo sapiens
267 ATXN3 4287
Affinity Capture-MS Homo sapiens
268 HAVCR2  
Affinity Capture-Western Homo sapiens
269 LBP 3929
Two-hybrid Homo sapiens
270 CDKN2A 1029
Affinity Capture-MS Homo sapiens
271 RNF149 284996
Affinity Capture-Western Homo sapiens
272 PRIM2 5558
Affinity Capture-MS Homo sapiens
273 DERL2 51009
Affinity Capture-Western Homo sapiens
274 MYPN 84665
Affinity Capture-MS Homo sapiens
275 OXSR1 9943
Affinity Capture-MS Homo sapiens
276 HSPA13 6782
Two-hybrid Homo sapiens
277 TSG101 7251
Affinity Capture-MS Homo sapiens
278 APP 351
Affinity Capture-Western Homo sapiens
279 KIAA1429 25962
Affinity Capture-MS Homo sapiens
280 GTF2F2 2963
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
281 PCK1 5105
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
282 UBQLN1 29979
Two-hybrid Homo sapiens
283 NR1H2  
Two-hybrid Homo sapiens
284 SERPINH1 871
Two-hybrid Homo sapiens
285 PDF  
Affinity Capture-MS Homo sapiens
286 NDUFA6  
Two-hybrid Homo sapiens
287 RB1 5925
Affinity Capture-MS Homo sapiens
288 APLP2 334
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
289 ACVR1B 91
Two-hybrid Homo sapiens
290 VCP 7415
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
291 CYSRT1 375791
Two-hybrid Homo sapiens
292 ARRDC3 57561
Affinity Capture-MS Homo sapiens
293 TDGF1  
Two-hybrid Homo sapiens
294 CEBPA  
Protein-peptide Homo sapiens
295 DNAJB11 51726
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
296 CD93  
Two-hybrid Homo sapiens
297 Asna1 56495
Affinity Capture-MS Mus musculus
298 USP32 84669
Affinity Capture-MS Homo sapiens
299 CTAG1A  
Two-hybrid Homo sapiens
300 PDE12 201626
Affinity Capture-MS Homo sapiens
301 LPPR3  
Two-hybrid Homo sapiens
302 Myh9 17886
Affinity Capture-MS Mus musculus
303 AMBRA1  
Affinity Capture-MS Homo sapiens
304 HIST2H3C 126961
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
305 DMKN  
Two-hybrid Homo sapiens
306 CHN2  
Two-hybrid Homo sapiens
307 EDN1  
Two-hybrid Homo sapiens
308 RLIM 51132
Affinity Capture-MS Homo sapiens
309 Smad3  
Affinity Capture-MS Mus musculus
310 CERK 64781
Affinity Capture-MS Homo sapiens
311 ETF1 2107
Affinity Capture-MS Homo sapiens
312 PLD5  
Affinity Capture-MS Homo sapiens
313 UACA 55075
Affinity Capture-MS Homo sapiens
314 ECHS1 1892
Affinity Capture-MS Homo sapiens
315 FBXO38 81545
Proximity Label-MS Homo sapiens
316 TCIRG1 10312
Affinity Capture-MS Homo sapiens
317 MAPK6  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
318 MYOF 26509
Affinity Capture-MS Homo sapiens
319 Get4  
Affinity Capture-MS Mus musculus
320 KCNAB2 8514
Affinity Capture-MS Homo sapiens
321 MAP3K4 4216
Affinity Capture-MS Homo sapiens
322 RNF123 63891
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
323 FNDC3A 22862
Affinity Capture-MS Homo sapiens
324 PLA2G2A 5320
Two-hybrid Homo sapiens
325 SERPINI2  
Two-hybrid Homo sapiens
326 NDUFB11 54539
Two-hybrid Homo sapiens
327 UBXN1 51035
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
328 BAIAP2L1 55971
Affinity Capture-MS Homo sapiens
329 IKBKAP 8518
Two-hybrid Homo sapiens
330 PPP4C 5531
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
331 SIRT6  
Affinity Capture-MS Homo sapiens
332 HECTD3 79654
Affinity Capture-MS Homo sapiens
333 UVSSA  
Affinity Capture-MS Homo sapiens
334 RP2 6102
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
335 RPAP1  
Affinity Capture-MS Homo sapiens
336 CDK18 5129
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
337 MAGED1 9500
Affinity Capture-MS Homo sapiens
338 IPO4 79711
Affinity Capture-MS Homo sapiens
339 PINK1  
Affinity Capture-MS Homo sapiens
340 ZUFSP 221302
Affinity Capture-MS Homo sapiens
341 C9orf72  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
342 KBTBD4  
Affinity Capture-MS Homo sapiens
343 WDHD1  
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here