Gene description for PPP1CB
Gene name protein phosphatase 1, catalytic subunit, beta isozyme
Gene symbol PPP1CB
Other names/aliases HEL-S-80p
PP-1B
PP1B
PP1beta
PPP1CD
Species Homo sapiens
 Database cross references - PPP1CB
ExoCarta ExoCarta_5500
Vesiclepedia VP_5500
Entrez Gene 5500
HGNC 9282
MIM 600590
UniProt P62140  
 PPP1CB identified in sEVs derived from the following tissue/cell type
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 35918900    
Breast cancer cells 35918900    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Saliva 19199708    
T lymphocytes 34108659    
Thymus 23844026    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for PPP1CB
Molecular Function
    protein serine/threonine phosphatase activity GO:0004722 IBA
    protein serine/threonine phosphatase activity GO:0004722 TAS
    protein binding GO:0005515 IPI
    phosphatase activity GO:0016791 ISS
    myosin phosphatase activity GO:0017018 ISS
    protein kinase binding GO:0019901 IPI
    calmodulin-dependent protein phosphatase activity GO:0033192 IEA
    metal ion binding GO:0046872 IEA
    myosin-light-chain-phosphatase activity GO:0050115 IDA
    histone H2AXS140 phosphatase activity GO:0140791 IEA
    RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity GO:0180004 IEA
    RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity GO:0180005 IEA
    RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity GO:0180006 IEA
    RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity GO:0180007 IEA
    RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity GO:0180008 IEA
    MAP kinase serine/threonine phosphatase activity GO:1990439 IEA
Biological Process
    MAPK cascade GO:0000165 TAS
    glycogen metabolic process GO:0005977 IEA
    chromatin remodeling GO:0006338 IEA
    regulation of transcription by RNA polymerase II GO:0006357 IEA
    protein dephosphorylation GO:0006470 ISS
    regulation of cell adhesion GO:0030155 IDA
    circadian regulation of gene expression GO:0032922 IBA
    circadian regulation of gene expression GO:0032922 ISS
    regulation of circadian rhythm GO:0042752 IBA
    regulation of circadian rhythm GO:0042752 IMP
    entrainment of circadian clock by photoperiod GO:0043153 ISS
    cell division GO:0051301 IEA
Subcellular Localization
    chromosome, telomeric region GO:0000781 IDA
    nucleus GO:0005634 HDA
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    nucleolus GO:0005730 IEA
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    focal adhesion GO:0005925 HDA
    extracellular exosome GO:0070062 HDA
    PTW/PP1 phosphatase complex GO:0072357 IDA
 Experiment description of studies that identified PPP1CB in sEVs
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
8
Experiment ID 1334
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
9
Experiment ID 1336
MISEV standards
Biophysical techniques
✔
CD9
Enriched markers
✔
ACTB
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35918900    
Organism Homo sapiens
Experiment description Characterization of protein complexes in extracellular vesicles by intact extracellular vesicle crosslinking mass spectrometry (iEVXL)
Authors "Bauzá-Martinez J, Armony G, Pronker MF, Wu W. "
Journal name J Extracell Vesicles
Publication year 2022
Sample Breast cancer cells
Sample name LM2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectometry
10
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
13
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
14
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
19
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
20
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
23
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
25
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
27
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
34
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
36
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PPP1CB
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CDCA2 157313
Affinity Capture-MS Homo sapiens
2 PQBP1  
Affinity Capture-MS Homo sapiens
3 RASSF8 11228
Affinity Capture-MS Homo sapiens
4 DAG1 1605
Co-fractionation Homo sapiens
5 TPM2 7169
Affinity Capture-MS Homo sapiens
6 CSNK1A1 1452
Co-fractionation Homo sapiens
7 Calml3  
Affinity Capture-MS Mus musculus
8 BRCA1 672
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
9 MAP4 4134
Co-fractionation Homo sapiens
10 KIF20A 10112
Affinity Capture-MS Homo sapiens
11 UBC 7316
Affinity Capture-MS Homo sapiens
12 INTS1 26173
Affinity Capture-MS Homo sapiens
13 ISG15 9636
Affinity Capture-MS Homo sapiens
14 PPP1R3C  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
15 ABLIM1 3983
Affinity Capture-MS Homo sapiens
16 MATR3 9782
Affinity Capture-MS Homo sapiens
17 ACTR3 10096
Affinity Capture-MS Homo sapiens
18 AP2A1 160
Affinity Capture-MS Homo sapiens
19 PACS1 55690
Affinity Capture-MS Homo sapiens
20 TRIOBP 11078
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
21 PPP1R18 170954
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 CALD1 800
Affinity Capture-MS Homo sapiens
23 TLK1  
Affinity Capture-MS Homo sapiens
24 SFRP1 6422
Affinity Capture-Western Homo sapiens
25 GSPT1 2935
Co-fractionation Homo sapiens
26 MECP2 4204
Affinity Capture-MS Homo sapiens
27 WDR5 11091
Co-fractionation Homo sapiens
28 ZFYVE9  
Two-hybrid Homo sapiens
29 EEF1A1 1915
Co-fractionation Homo sapiens
30 TES 26136
Affinity Capture-MS Homo sapiens
31 KIF14 9928
Affinity Capture-MS Homo sapiens
32 RBMX 27316
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
33 UNK  
Affinity Capture-RNA Homo sapiens
34 HEXIM1 10614
Affinity Capture-MS Homo sapiens
35 AURKA 6790
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
36 RBM12B  
Affinity Capture-MS Homo sapiens
37 CAPZA1 829
Affinity Capture-MS Homo sapiens
38 SORBS2  
Affinity Capture-MS Homo sapiens
39 LUZP1 7798
Affinity Capture-MS Homo sapiens
40 MAPRE1 22919
Affinity Capture-MS Homo sapiens
41 PPP1R16B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 UBXN2B  
Affinity Capture-MS Homo sapiens
43 HDAC7  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
44 YAP1 10413
Affinity Capture-MS Homo sapiens
45 MYH9 4627
Affinity Capture-MS Homo sapiens
46 ACTN4 81
Affinity Capture-MS Homo sapiens
47 OGT 8473
Co-fractionation Homo sapiens
48 ARHGAP11A  
Affinity Capture-MS Homo sapiens
49 MEOX2  
Two-hybrid Homo sapiens
50 RRP1B 23076
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
51 PAK2 5062
Affinity Capture-Western Homo sapiens
52 ST5 6764
Affinity Capture-MS Homo sapiens
53 PPP1R8 5511
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
54 PPP1R12B 4660
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
55 ZNF326 284695
Affinity Capture-MS Homo sapiens
56 ANLN 54443
Affinity Capture-MS Homo sapiens
57 DDX5 1655
Co-fractionation Homo sapiens
58 DST 667
Affinity Capture-MS Homo sapiens
59 SFRP5  
Affinity Capture-Western Homo sapiens
60 SIRT7  
Affinity Capture-MS Homo sapiens
61 CD2BP2 10421
Affinity Capture-MS Homo sapiens
62 LMO7 4008
Affinity Capture-MS Homo sapiens
63 LMTK2 22853
Two-hybrid Homo sapiens
64 MYO19  
Affinity Capture-MS Homo sapiens
65 MYO1C 4641
Affinity Capture-MS Homo sapiens
66 AATK  
Two-hybrid Homo sapiens
67 Cep72  
Affinity Capture-MS Mus musculus
68 RPA3 6119
Proximity Label-MS Homo sapiens
69 HSPA1A 3303
Co-fractionation Homo sapiens
70 HSPA4 3308
Affinity Capture-Western Homo sapiens
71 KAT8  
Co-fractionation Homo sapiens
72 AKT1 207
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
73 TPM4 7171
Affinity Capture-MS Homo sapiens
74 TP53BP2  
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
75 DAB2 1601
Affinity Capture-MS Homo sapiens
76 WDR77 79084
Affinity Capture-MS Homo sapiens
77 SSFA2 6744
Affinity Capture-MS Homo sapiens
78 PLEC 5339
Affinity Capture-MS Homo sapiens
79 WDR92 116143
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 PPP1R11  
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
81 Sass6  
Affinity Capture-MS Mus musculus
82 NCL 4691
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
83 BCL2  
Affinity Capture-Western Homo sapiens
84 EIF4B 1975
Cross-Linking-MS (XL-MS) Homo sapiens
85 DAPK3 1613
Affinity Capture-MS Homo sapiens
86 CLTA 1211
Affinity Capture-MS Homo sapiens
87 ACO2 50
Affinity Capture-MS Homo sapiens
88 MISP 126353
Affinity Capture-MS Homo sapiens
89 ANXA2 302
Affinity Capture-MS Homo sapiens
90 GAS2L1 10634
Affinity Capture-MS Homo sapiens
91 PSMC4 5704
Co-fractionation Homo sapiens
92 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
93 DENR 8562
Co-fractionation Homo sapiens
94 MCM3 4172
Co-fractionation Homo sapiens
95 RBMXL1  
Affinity Capture-MS Homo sapiens
96 LUZP4  
Affinity Capture-MS Homo sapiens
97 KIF23 9493
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
98 GART 2618
Co-fractionation Homo sapiens
99 WDR82 80335
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 BTF3 689
Affinity Capture-MS Homo sapiens
101 DBN1 1627
Affinity Capture-MS Homo sapiens
102 PPP1R27  
Two-hybrid Homo sapiens
103 PPP1R9B 84687
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
104 MVK 4598
Co-fractionation Homo sapiens
105 CLTB 1212
Affinity Capture-MS Homo sapiens
106 UBXN2A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
107 URI1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 SAFB 6294
Affinity Capture-MS Homo sapiens
109 NCOR1  
Affinity Capture-Western Homo sapiens
110 CORO1B 57175
Affinity Capture-MS Homo sapiens
111 LRRC1 55227
Affinity Capture-MS Homo sapiens
112 MYO5B 4645
Affinity Capture-MS Homo sapiens
113 OSBP 5007
Co-fractionation Homo sapiens
114 ARPC4 10093
Affinity Capture-MS Homo sapiens
115 PRC1 9055
Affinity Capture-MS Homo sapiens
116 TAF15 8148
Affinity Capture-MS Homo sapiens
117 KHDRBS1 10657
Affinity Capture-MS Homo sapiens
118 HIST1H3A 8350
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
119 TPRN 286262
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 CTPS1 1503
Co-fractionation Homo sapiens
121 Wdr82  
Affinity Capture-MS Mus musculus
122 ASF1A 25842
Affinity Capture-MS Homo sapiens
123 TWF1 5756
Affinity Capture-MS Homo sapiens
124 GSK3B 2932
Affinity Capture-MS Homo sapiens
125 COBL  
Affinity Capture-MS Homo sapiens
126 VRK3 51231
Affinity Capture-MS Homo sapiens
127 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
128 RBM6 10180
Affinity Capture-MS Homo sapiens
129 RAI14 26064
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
130 PPP1R16A 84988
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
131 CSRNP2  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
132 Arrb2  
Affinity Capture-MS Mus musculus
133 CCNB1 891
Affinity Capture-Western Homo sapiens
134 DCAF7 10238
Affinity Capture-MS Homo sapiens
135 C20orf27 54976
Affinity Capture-MS Homo sapiens
136 RAD18  
Affinity Capture-MS Homo sapiens
137 TOX4  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 CTNNB1 1499
Affinity Capture-MS Homo sapiens
139 PPP1R2 5504
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
140 Ppp1r7 66385
Affinity Capture-MS Mus musculus
141 STON2 85439
Affinity Capture-MS Homo sapiens
142 HNRNPD 3184
Affinity Capture-MS Homo sapiens
143 POLR2E 5434
Affinity Capture-MS Homo sapiens
144 TJP1 7082
Affinity Capture-MS Homo sapiens
145 KANK2 25959
Two-hybrid Homo sapiens
146 YLPM1 56252
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
147 SPECC1 92521
Affinity Capture-MS Homo sapiens
148 GAS2L3  
Affinity Capture-MS Homo sapiens
149 PTK2 5747
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
150 NUAK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
151 SPTBN1 6711
Affinity Capture-MS Homo sapiens
152 CDK2 1017
Affinity Capture-MS Homo sapiens
153 TPM1 7168
Affinity Capture-MS Homo sapiens
154 MYC  
Affinity Capture-MS Homo sapiens
155 TMOD3 29766
Affinity Capture-MS Homo sapiens
156 DSTN 11034
Affinity Capture-MS Homo sapiens
157 DDRGK1 65992
Affinity Capture-MS Homo sapiens
158 AKAP2 11217
Affinity Capture-MS Homo sapiens
159 MPRIP 23164
Affinity Capture-MS Homo sapiens
160 UACA 55075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
161 RASSF7  
Affinity Capture-MS Homo sapiens
162 PARP1 142
Proximity Label-MS Homo sapiens
163 ILF3 3609
Affinity Capture-MS Homo sapiens
164 H3F3A 3020
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
165 MAX  
Affinity Capture-Western Homo sapiens
166 SIPA1 6494
Affinity Capture-MS Homo sapiens
167 RYR2 6262
Co-fractionation Homo sapiens
168 Myo1c 17913
Affinity Capture-MS Mus musculus
169 SIPA1L3  
Affinity Capture-MS Homo sapiens
170 ARPC2 10109
Affinity Capture-MS Homo sapiens
171 CAPZA2 830
Affinity Capture-MS Homo sapiens
172 ACTRT1  
Affinity Capture-MS Homo sapiens
173 Myh10 77579
Affinity Capture-MS Mus musculus
174 Tox4  
Affinity Capture-MS Mus musculus
175 MINPP1 9562
Affinity Capture-MS Homo sapiens
176 KRAS 3845
Negative Genetic Homo sapiens
177 SSH2  
Affinity Capture-MS Homo sapiens
178 S100A2 6273
Co-fractionation Homo sapiens
179 PDRG1  
Affinity Capture-MS Homo sapiens
180 CCND3  
Affinity Capture-Western Homo sapiens
181 SFRP2  
Affinity Capture-Western Homo sapiens
182 CDC34 997
Affinity Capture-Western Homo sapiens
183 ZDHHC5 25921
Affinity Capture-MS Homo sapiens
184 SHOC2 8036
Affinity Capture-MS Homo sapiens
185 ACTR2 10097
Affinity Capture-MS Homo sapiens
186 AKAP11 11215
Affinity Capture-Western Homo sapiens
187 ARHGAP21 57584
Affinity Capture-MS Homo sapiens
188 PLCL2 23228
Affinity Capture-MS Homo sapiens
189 LIMCH1 22998
Affinity Capture-MS Homo sapiens
190 EPS15 2060
Affinity Capture-MS Homo sapiens
191 MYO5C 55930
Affinity Capture-MS Homo sapiens
192 PSMD10 5716
Co-fractionation Homo sapiens
193 PTPN1 5770
Co-fractionation Homo sapiens
194 PPP1R10  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 GYS1 2997
Affinity Capture-MS Homo sapiens
196 CAPZB 832
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
197 TRIM28 10155
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
198 ZNF638 27332
Affinity Capture-MS Homo sapiens
199 LIG1 3978
Co-fractionation Homo sapiens
200 IQGAP1 8826
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 PPP1R7 5510
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
202 RHOB 388
Proximity Label-MS Homo sapiens
203 ATG16L1 55054
Affinity Capture-MS Homo sapiens
204 CSNK2B 1460
Two-hybrid Homo sapiens
205 YAF2  
Affinity Capture-MS Homo sapiens
206 USP37  
Proximity Label-MS Homo sapiens
207 MYO18A 399687
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 ZFYVE16  
Proximity Label-MS Homo sapiens
209 CHCHD3 54927
Two-hybrid Homo sapiens
210 Taf15  
Affinity Capture-MS Mus musculus
211 RACGAP1 29127
Affinity Capture-MS Homo sapiens
212 CSRNP1  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
213 MAPT  
Biochemical Activity Homo sapiens
214 RASSF9  
Affinity Capture-MS Homo sapiens
215 SAFB2 9667
Affinity Capture-MS Homo sapiens
216 NTRK1 4914
Affinity Capture-MS Homo sapiens
217 FLNB 2317
Affinity Capture-MS Homo sapiens
218 ACTB 60
Affinity Capture-MS Homo sapiens
219 DHX9 1660
Affinity Capture-MS Homo sapiens
220 PIK3C2A 5286
Affinity Capture-MS Homo sapiens
221 Ppp1r10  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
222 TMEM33 55161
Affinity Capture-MS Homo sapiens
223 ACTG1 71
Affinity Capture-MS Homo sapiens
224 KIF18A  
Affinity Capture-MS Homo sapiens
225 ECT2 1894
Affinity Capture-MS Homo sapiens
226 PPP1R2P3  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
227 PPP1R37 284352
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
228 MYO5A 4644
Affinity Capture-MS Homo sapiens
229 GLI1  
Affinity Capture-MS Homo sapiens
230 ACE2 59272
Affinity Capture-MS Homo sapiens
231 MDM4  
Affinity Capture-Western Homo sapiens
232 CORO1C 23603
Affinity Capture-MS Homo sapiens
233 BASP1 10409
Affinity Capture-MS Homo sapiens
234 APOBEC3B 9582
Affinity Capture-MS Homo sapiens
235 SYNPO 11346
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
236 SEC16A 9919
Affinity Capture-MS Homo sapiens
237 TOP1 7150
Affinity Capture-MS Homo sapiens
238 CFL2 1073
Affinity Capture-MS Homo sapiens
239 ACTN2 88
Two-hybrid Homo sapiens
240 PPP6C 5537
Affinity Capture-MS Homo sapiens
241 FLII 2314
Affinity Capture-MS Homo sapiens
242 KIAA1671  
Affinity Capture-MS Homo sapiens
243 SIK2  
Affinity Capture-MS Homo sapiens
244 HSPA9 3313
Co-fractionation Homo sapiens
245 TPM3 7170
Affinity Capture-MS Homo sapiens
246 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
247 CCT8 10694
Affinity Capture-MS Homo sapiens
248 SPTBN2 6712
Affinity Capture-MS Homo sapiens
249 DDX3X 1654
Affinity Capture-MS Homo sapiens
250 RDX 5962
Co-fractionation Homo sapiens
251 MNDA 4332
Affinity Capture-MS Homo sapiens
252 ACTA1 58
Affinity Capture-MS Homo sapiens
253 PPP1R12A 4659
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
254 INF2 64423
Affinity Capture-MS Homo sapiens
255 HNRNPH3 3189
Affinity Capture-MS Homo sapiens
256 FLNA 2316
Affinity Capture-MS Homo sapiens
257 MYO1E 4643
Affinity Capture-MS Homo sapiens
258 SERBP1 26135
Affinity Capture-MS Homo sapiens
259 SH2D4A 63898
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
260 AR 367
Affinity Capture-MS Homo sapiens
261 SSRP1 6749
Affinity Capture-MS Homo sapiens
262 RIF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
263 CDKN2A 1029
Affinity Capture-Western Homo sapiens
264 UBE2H 7328
Affinity Capture-MS Homo sapiens
265 RIT1 6016
Negative Genetic Homo sapiens
266 PPP1R2P9  
Two-hybrid Homo sapiens
267 PPP1R3A  
Affinity Capture-MS Homo sapiens
268 PSMD11 5717
Co-fractionation Homo sapiens
269 USP5 8078
Co-fractionation Homo sapiens
270 KPNB1 3837
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
271 DEC1  
Two-hybrid Homo sapiens
272 CALM1 801
Affinity Capture-MS Homo sapiens
273 CFL1 1072
Affinity Capture-MS Homo sapiens
274 GSK3A 2931
Affinity Capture-MS Homo sapiens
275 PPP1CC 5501
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
276 RPS11 6205
Cross-Linking-MS (XL-MS) Homo sapiens
277 AFAP1 60312
Affinity Capture-MS Homo sapiens
278 SPECC1L 23384
Affinity Capture-MS Homo sapiens
279 PPP2R5C 5527
Two-hybrid Homo sapiens
280 KIF5B 3799
Co-fractionation Homo sapiens
281 SCRIB 23513
Affinity Capture-MS Homo sapiens
282 YES1 7525
Affinity Capture-MS Homo sapiens
283 FBXW7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
284 IMPDH2 3615
Co-fractionation Homo sapiens
285 NCOA5  
Affinity Capture-MS Homo sapiens
286 CALM3 808
Affinity Capture-MS Homo sapiens
287 C14orf180  
Two-hybrid Homo sapiens
288 ABCE1 6059
Affinity Capture-MS Homo sapiens
289 MYO1B 4430
Affinity Capture-MS Homo sapiens
290 EED  
Affinity Capture-MS Homo sapiens
291 INTS6 26512
Affinity Capture-MS Homo sapiens
292 PPP1R15B  
Affinity Capture-MS Homo sapiens
293 SNX27 81609
Affinity Capture-MS Homo sapiens
294 SMARCB1 6598
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Phenotypic Enhancement Homo sapiens
295 WDR1 9948
Affinity Capture-MS Homo sapiens
296 E2F4  
Affinity Capture-MS Homo sapiens
297 CLOCK  
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
298 PPP1CA 5499
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
299 RORC 6097
Two-hybrid Homo sapiens
300 UXT 8409
Affinity Capture-MS Homo sapiens
301 TMOD1  
Affinity Capture-MS Homo sapiens
302 NONO 4841
Reconstituted Complex Homo sapiens
303 CCDC85C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
304 CYSRT1 375791
Two-hybrid Homo sapiens
305 BMP2K 55589
Affinity Capture-MS Homo sapiens
306 DYNLL2 140735
Affinity Capture-MS Homo sapiens
307 PPP1R12C 54776
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
308 GNL3L 54552
Cross-Linking-MS (XL-MS) Homo sapiens
309 CALML3 810
Affinity Capture-MS Homo sapiens
310 LIMA1 51474
Affinity Capture-MS Homo sapiens
311 ACTN1 87
Affinity Capture-MS Homo sapiens
312 CPSF1 29894
Co-fractionation Homo sapiens
313 IPO5 3843
Co-fractionation Homo sapiens
314 CLINT1 9685
Affinity Capture-MS Homo sapiens
315 Myh9 17886
Affinity Capture-MS Mus musculus
316 CUL3 8452
Affinity Capture-MS Homo sapiens
317 RLIM 51132
Affinity Capture-MS Homo sapiens
318 HCFC1 3054
Co-fractionation Homo sapiens
319 Itga5 16402
Affinity Capture-MS Mus musculus
320 CTTN 2017
Affinity Capture-MS Homo sapiens
321 RAB35 11021
Proximity Label-MS Homo sapiens
322 PRKCI 5584
Co-fractionation Homo sapiens
323 MYO6 4646
Affinity Capture-MS Homo sapiens
324 PSAP 5660
Co-fractionation Homo sapiens
325 RPAP3 79657
Affinity Capture-MS Homo sapiens
326 NFKB1 4790
Co-fractionation Homo sapiens
327 SIRT2 22933
Affinity Capture-MS Homo sapiens
328 CCND1 595
Affinity Capture-Western Homo sapiens
329 PLEKHG3 26030
Affinity Capture-MS Homo sapiens
330 PPP1R13B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
331 UBXN1 51035
Affinity Capture-MS Homo sapiens
332 PPP1R15A  
Affinity Capture-Western Homo sapiens
333 LBR 3930
Affinity Capture-Western Homo sapiens
334 DHX15 1665
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
335 NEXN 91624
Affinity Capture-MS Homo sapiens
336 SPTAN1 6709
Affinity Capture-MS Homo sapiens
337 MYLK 4638
Affinity Capture-MS Homo sapiens
338 PAPOLA 10914
Co-fractionation Homo sapiens
339 SVIL 6840
Affinity Capture-MS Homo sapiens
340 SSU72 29101
Co-fractionation Homo sapiens
341 PPP1R13L 10848
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
342 WBP11  
Affinity Capture-MS Homo sapiens
343 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
344 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
345 TAF2  
Affinity Capture-MS Homo sapiens
346 TNFAIP1 7126
Affinity Capture-MS Homo sapiens
347 ZNF106  
Affinity Capture-MS Homo sapiens
348 KIF18B 146909
Affinity Capture-MS Homo sapiens
349 CAD 790
Co-fractionation Homo sapiens
350 SPATC1L  
Two-hybrid Homo sapiens
351 PIH1D1  
Affinity Capture-MS Homo sapiens
352 C9orf72  
Affinity Capture-MS Homo sapiens
353 METTL17  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
354 INTU  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PPP1CB is involved
PathwayEvidenceSource
Cell Cycle TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Circadian Clock IEA Reactome
Disease TAS Reactome
Diseases of signal transduction by growth factor receptors and second messengers TAS Reactome
Downregulation of TGF-beta receptor signaling IEA Reactome
G2/M Transition TAS Reactome
Gain-of-function MRAS complexes activate RAF signaling TAS Reactome
Infectious disease TAS Reactome
MAPK family signaling cascades TAS Reactome
MAPK1/MAPK3 signaling TAS Reactome
Maturation of hRSV A proteins TAS Reactome
Metabolism IEA Reactome
Metabolism of lipids IEA Reactome
Mitotic G2-G2/M phases TAS Reactome
Oncogenic MAPK signaling TAS Reactome
RAF activation TAS Reactome
RAF/MAP kinase cascade TAS Reactome
Regulation of PLK1 Activity at G2/M Transition TAS Reactome
Respiratory syncytial virus (RSV) genome replication, transcription and translation TAS Reactome
Respiratory Syncytial Virus Infection Pathway TAS Reactome
RHO GTPase Effectors IEA Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPases activate CIT IEA Reactome
RHO GTPases activate PAKs IEA Reactome
RHO GTPases activate PAKs TAS Reactome
RHO GTPases activate PKNs IEA Reactome
RHO GTPases activate PKNs TAS Reactome
RHO GTPases Activate ROCKs IEA Reactome
SHOC2 M1731 mutant abolishes MRAS complex function TAS Reactome
Signal Transduction IEA Reactome
Signal Transduction TAS Reactome
Signaling by MRAS-complex mutants TAS Reactome
Signaling by Rho GTPases IEA Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 IEA Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
Signaling by TGF-beta Receptor Complex IEA Reactome
Signaling by TGFB family members IEA Reactome
TGF-beta receptor signaling activates SMADs IEA Reactome
Triglyceride catabolism IEA Reactome
Triglyceride metabolism IEA Reactome
Viral Infection Pathways TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here