Gene description for GSPT1
Gene name G1 to S phase transition 1
Gene symbol GSPT1
Other names/aliases 551G9.2
ETF3A
GST1
eRF3a
Species Homo sapiens
 Database cross references - GSPT1
ExoCarta ExoCarta_2935
Vesiclepedia VP_2935
Entrez Gene 2935
HGNC 4621
MIM 139259
UniProt P15170  
 GSPT1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for GSPT1
Molecular Function
    RNA binding GO:0003723 HDA
    translation release factor activity GO:0003747 IBA
    translation release factor activity GO:0003747 IDA
    translation release factor activity GO:0003747 IMP
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 IDA
    GTPase activity GO:0003924 TAS
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IEA
Biological Process
    G1/S transition of mitotic cell cycle GO:0000082 TAS
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 TAS
    translation GO:0006412 IBA
    translational termination GO:0006415 IDA
    regulation of translational termination GO:0006449 IMP
    protein methylation GO:0006479 IDA
Subcellular Localization
    cytoplasm GO:0005737 NAS
    cytosol GO:0005829 TAS
    translation release factor complex GO:0018444 IBA
    translation release factor complex GO:0018444 IDA
    translation release factor complex GO:0018444 IPI
    cytosolic ribosome GO:0022626 IDA
 Experiment description of studies that identified GSPT1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
10
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
22
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for GSPT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CRBN  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
2 EIF3A 8661
Affinity Capture-MS Homo sapiens
3 RIT1 6016
Negative Genetic Homo sapiens
4 MCM3 4172
Co-fractionation Homo sapiens
5 UBE2H 7328
Affinity Capture-MS Homo sapiens
6 RPL26L1 51121
Affinity Capture-MS Homo sapiens
7 NCBP1 4686
Co-fractionation Homo sapiens
8 PPP1CB 5500
Co-fractionation Homo sapiens
9 XIAP  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
10 RPS3A 6189
Affinity Capture-MS Homo sapiens
11 PSMD6 9861
Co-fractionation Homo sapiens
12 RPL38 6169
Affinity Capture-MS Homo sapiens
13 EIF2S3 1968
Affinity Capture-MS Homo sapiens
14 EIF3K 27335
Affinity Capture-MS Homo sapiens
15 RPS17 6218
Affinity Capture-MS Homo sapiens
16 SRPRB 58477
Affinity Capture-MS Homo sapiens
17 NKRF 55922
Affinity Capture-MS Homo sapiens
18 DNTTIP1 116092
Affinity Capture-MS Homo sapiens
19 ATP6V1C1 528
Co-fractionation Homo sapiens
20 LARP1 23367
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
21 RPL13A 23521
Affinity Capture-MS Homo sapiens
22 CAP1 10487
Cross-Linking-MS (XL-MS) Homo sapiens
23 TMEM184A  
Affinity Capture-MS Homo sapiens
24 PBK  
Co-fractionation Homo sapiens
25 RPS19 6223
Affinity Capture-MS Homo sapiens
26 RPL10 6134
Affinity Capture-MS Homo sapiens
27 TRIM33 51592
Co-fractionation Homo sapiens
28 ZFR 51663
Affinity Capture-MS Homo sapiens
29 RPL14 9045
Affinity Capture-MS Homo sapiens
30 EIF4A1 1973
Affinity Capture-MS Homo sapiens
31 HNRNPR 10236
Affinity Capture-MS Homo sapiens
32 PSMD10 5716
Co-fractionation Homo sapiens
33 SRP72 6731
Affinity Capture-MS Homo sapiens
34 GFRA1 2674
Co-fractionation Homo sapiens
35 LIG1 3978
Co-fractionation Homo sapiens
36 FAU 2197
Affinity Capture-MS Homo sapiens
37 RPS3 6188
Affinity Capture-MS Homo sapiens
38 ILF2 3608
Affinity Capture-MS Homo sapiens
39 LRPPRC 10128
Co-fractionation Homo sapiens
40 RPS18 6222
Affinity Capture-MS Homo sapiens
41 RNH1 6050
Co-fractionation Homo sapiens
42 SRP54 6729
Affinity Capture-MS Homo sapiens
43 RPS6 6194
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
44 RPL4 6124
Affinity Capture-MS Homo sapiens
45 RPS20 6224
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
46 RUVBL1 8607
Co-fractionation Homo sapiens
47 GSPT2 23708
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
48 RDX 5962
Co-fractionation Homo sapiens
49 RPL39 6170
Affinity Capture-MS Homo sapiens
50 RPL24 6152
Affinity Capture-MS Homo sapiens
51 DYNC1LI2 1783
Co-fractionation Homo sapiens
52 ACTN1 87
Affinity Capture-MS Homo sapiens
53 PABPC4L 132430
Affinity Capture-MS Homo sapiens
54 GNS 2799
Co-fractionation Homo sapiens
55 KIF5B 3799
Co-fractionation Homo sapiens
56 EIF3B 8662
Affinity Capture-MS Homo sapiens
57 IMPDH2 3615
Co-fractionation Homo sapiens
58 SEC23IP 11196
Co-fractionation Homo sapiens
59 IQGAP1 8826
Co-fractionation Homo sapiens
60 PSMD12 5718
Co-fractionation Homo sapiens
61 HSPH1 10808
Co-fractionation Homo sapiens
62 SSR1 6745
Affinity Capture-MS Homo sapiens
63 WASH1 100287171
Affinity Capture-MS Homo sapiens
64 ABCE1 6059
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
65 EIF3E 3646
Affinity Capture-MS Homo sapiens
66 HINFP  
Two-hybrid Homo sapiens
67 ATG7 10533
Co-fractionation Homo sapiens
68 GNL3 26354
Affinity Capture-MS Homo sapiens
69 GOLGA4  
Co-fractionation Homo sapiens
70 PRDX4 10549
Co-fractionation Homo sapiens
71 MTDH 92140
Affinity Capture-MS Homo sapiens
72 RPL34 6164
Affinity Capture-MS Homo sapiens
73 CTPS1 1503
Affinity Capture-MS Homo sapiens
74 MYCN  
Affinity Capture-MS Homo sapiens
75 WDR5 11091
Co-fractionation Homo sapiens
76 RPS11 6205
Affinity Capture-MS Homo sapiens
77 PABPC4 8761
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
78 RPL19 6143
Affinity Capture-MS Homo sapiens
79 RBM8A 9939
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
80 DYNC1H1 1778
Co-fractionation Homo sapiens
81 ATXN2 6311
Affinity Capture-MS Homo sapiens
82 CCT2 10576
Co-fractionation Homo sapiens
83 RPS23 6228
Affinity Capture-MS Homo sapiens
84 RPL27 6155
Affinity Capture-MS Homo sapiens
85 PPP1CA 5499
Co-fractionation Homo sapiens
86 RPL30 6156
Affinity Capture-MS Homo sapiens
87 NAPA 8775
Co-fractionation Homo sapiens
88 USP10 9100
Affinity Capture-MS Homo sapiens
89 RNF213 57674
Co-fractionation Homo sapiens
90 RPL9 6133
Affinity Capture-MS Homo sapiens
91 PARK2  
Affinity Capture-MS Homo sapiens
92 KLC1 3831
Co-fractionation Homo sapiens
93 COPE 11316
Affinity Capture-MS Homo sapiens
94 DRG1 4733
Affinity Capture-MS Homo sapiens
95 ARMC8 25852
Affinity Capture-MS Homo sapiens
96 SRSF3 6428
Co-fractionation Homo sapiens
97 PSMD11 5717
Co-fractionation Homo sapiens
98 STAU1 6780
Affinity Capture-MS Homo sapiens
99 ADRM1 11047
Co-fractionation Homo sapiens
100 RTF1 23168
Co-fractionation Homo sapiens
101 PAN2  
Affinity Capture-MS Homo sapiens
102 UBR5 51366
Affinity Capture-Western Homo sapiens
103 PABPC1 26986
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
104 CDH1 999
Proximity Label-MS Homo sapiens
105 MYH9 4627
Co-fractionation Homo sapiens
106 VCP 7415
Affinity Capture-MS Homo sapiens
107 NTRK1 4914
Affinity Capture-MS Homo sapiens
108 RPL31 6160
Affinity Capture-MS Homo sapiens
109 RPS7 6201
Affinity Capture-MS Homo sapiens
110 RPS24 6229
Affinity Capture-MS Homo sapiens
111 U2AF2 11338
Co-fractionation Homo sapiens
112 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
113 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
114 PI4KB 5298
Co-fractionation Homo sapiens
115 DNAJA1 3301
Co-fractionation Homo sapiens
116 CARM1 10498
Co-fractionation Homo sapiens
117 RPL36 25873
Affinity Capture-MS Homo sapiens
118 PSMC5 5705
Co-fractionation Homo sapiens
119 RPL27A 6157
Affinity Capture-MS Homo sapiens
120 RPLP1 6176
Affinity Capture-MS Homo sapiens
121 PIK3R1 5295
Two-hybrid Homo sapiens
122 DHX9 1660
Affinity Capture-MS Homo sapiens
123 PRKAR2A 5576
Affinity Capture-MS Homo sapiens
124 MAGOH 4116
Cross-Linking-MS (XL-MS) Homo sapiens
125 RPLP0 6175
Affinity Capture-MS Homo sapiens
126 RPS16 6217
Affinity Capture-MS Homo sapiens
127 SRP68 6730
Affinity Capture-MS Homo sapiens
128 PPM1G 5496
Affinity Capture-MS Homo sapiens
129 CEBPA  
Protein-peptide Homo sapiens
130 DYNC1I2 1781
Co-fractionation Homo sapiens
131 PAIP1 10605
Affinity Capture-MS Homo sapiens
132 EIF4G3 8672
Affinity Capture-MS Homo sapiens
133 RPL11 6135
Affinity Capture-MS Homo sapiens
134 SSR4 6748
Affinity Capture-MS Homo sapiens
135 HEATR6  
Co-fractionation Homo sapiens
136 SNX1 6642
Co-fractionation Homo sapiens
137 ATXN1 6310
Two-hybrid Homo sapiens
138 HNRNPDL 9987
Affinity Capture-MS Homo sapiens
139 BIRC2  
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
140 EIF3G 8666
Affinity Capture-MS Homo sapiens
141 HSPA5 3309
Co-fractionation Homo sapiens
142 RPL32 6161
Affinity Capture-MS Homo sapiens
143 ASCC3 10973
Affinity Capture-MS Homo sapiens
144 RPL10A 4736
Affinity Capture-MS Homo sapiens
145 IPO5 3843
Co-fractionation Homo sapiens
146 RPLP2 6181
Affinity Capture-MS Homo sapiens
147 MAP4 4134
Co-fractionation Homo sapiens
148 RPL7A 6130
Affinity Capture-MS Homo sapiens
149 RPS2 6187
Affinity Capture-MS Homo sapiens
150 PAN3 255967
Affinity Capture-MS Homo sapiens
151 XPO1 7514
Affinity Capture-MS Homo sapiens
152 EIF4G1 1981
Affinity Capture-MS Homo sapiens
153 SAP30L  
Affinity Capture-MS Homo sapiens
154 ASCC1 51008
Affinity Capture-MS Homo sapiens
155 PSMD13 5719
Co-fractionation Homo sapiens
156 RPL35 11224
Affinity Capture-MS Homo sapiens
157 EEF2 1938
Co-fractionation Homo sapiens
158 DHX29 54505
Affinity Capture-MS Homo sapiens
159 RPL21 6144
Affinity Capture-MS Homo sapiens
160 RPAP3 79657
Co-fractionation Homo sapiens
161 RPS8 6202
Affinity Capture-MS Homo sapiens
162 CTTN 2017
Co-fractionation Homo sapiens
163 RPL3 6122
Affinity Capture-MS Homo sapiens
164 SLK 9748
Co-fractionation Homo sapiens
165 ETF1 2107
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
166 EIF3F 8665
Affinity Capture-MS Homo sapiens
167 EIF4E 1977
Affinity Capture-MS Homo sapiens
168 DHX30 22907
Affinity Capture-MS Homo sapiens
169 SMG1 23049
Co-fractionation Homo sapiens
170 EIF2S2 8894
Affinity Capture-MS Homo sapiens
171 VBP1 7411
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
172 GLUD1 2746
Affinity Capture-MS Homo sapiens
173 PRKCI 5584
Co-fractionation Homo sapiens
174 EFTUD2 9343
Affinity Capture-MS Homo sapiens
175 RPS27 6232
Affinity Capture-MS Homo sapiens
176 LUC7L2 51631
Co-fractionation Homo sapiens
177 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
178 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
179 MYC  
Affinity Capture-MS Homo sapiens
180 RPA3 6119
Proximity Label-MS Homo sapiens
181 DYNC1LI1 51143
Co-fractionation Homo sapiens
182 RPS13 6207
Affinity Capture-MS Homo sapiens
183 MCMBP 79892
Co-fractionation Homo sapiens
184 DLST 1743
Co-fractionation Homo sapiens
185 RPS14 6208
Affinity Capture-MS Homo sapiens
186 HSPA1A 3303
Co-fractionation Homo sapiens
187 RPL22 6146
Affinity Capture-MS Homo sapiens
188 EIF3CL 728689
Affinity Capture-MS Homo sapiens
189 TCEB2 6923
Co-fractionation Homo sapiens
190 DDB1 1642
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
191 SNW1 22938
Affinity Capture-MS Homo sapiens
192 KTN1 3895
Affinity Capture-MS Homo sapiens
193 HSPA4L 22824
Co-fractionation Homo sapiens
194 CSDE1 7812
Co-fractionation Homo sapiens
195 HNRNPU 3192
Affinity Capture-MS Homo sapiens
196 UPF2 26019
Affinity Capture-MS Homo sapiens
197 GNB2L1 10399
Affinity Capture-MS Homo sapiens
198 MGEA5 10724
Co-fractionation Homo sapiens
199 EIF3D 8664
Affinity Capture-MS Homo sapiens
200 EIF3H 8667
Affinity Capture-MS Homo sapiens
201 U2SURP 23350
Affinity Capture-MS Homo sapiens
202 RPL13 6137
Affinity Capture-MS Homo sapiens
203 EIF2S1 1965
Affinity Capture-MS Homo sapiens
204 KIF2A 3796
Co-fractionation Homo sapiens
205 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
206 SPTAN1 6709
Co-fractionation Homo sapiens
207 PRRC2A 7916
Affinity Capture-MS Homo sapiens
208 RPS25 6230
Affinity Capture-MS Homo sapiens
209 GEMIN5 25929
Co-fractionation Homo sapiens
210 EIF3C 8663
Affinity Capture-MS Homo sapiens
211 ILF3 3609
Affinity Capture-MS Homo sapiens
212 CPSF6 11052
Co-fractionation Homo sapiens
213 TP53 7157
Affinity Capture-MS Homo sapiens
214 RPL6 6128
Affinity Capture-MS Homo sapiens
215 MARK2 2011
Affinity Capture-MS Homo sapiens
216 EIF3I 8668
Affinity Capture-MS Homo sapiens
217 RUVBL2 10856
Co-fractionation Homo sapiens
218 MCM5 4174
Co-fractionation Homo sapiens
219 H1FX 8971
Affinity Capture-MS Homo sapiens
220 PSMB7 5695
Co-fractionation Homo sapiens
221 NUFIP2 57532
Affinity Capture-MS Homo sapiens
222 KEAP1 9817
Affinity Capture-MS Homo sapiens
223 RPS21 6227
Affinity Capture-MS Homo sapiens
224 RPS12 6206
Affinity Capture-MS Homo sapiens
225 CHRM4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
226 RPS4X 6191
Affinity Capture-MS Homo sapiens
227 SQSTM1 8878
Proximity Label-MS Homo sapiens
228 DPPA4  
Affinity Capture-MS Homo sapiens
229 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
230 CAPZB 832
Co-fractionation Homo sapiens
231 RPS5 6193
Affinity Capture-MS Homo sapiens
232 RPS15A 6210
Affinity Capture-MS Homo sapiens
233 RPS15 6209
Affinity Capture-MS Homo sapiens
234 RPS26 6231
Affinity Capture-MS Homo sapiens
235 IDE 3416
Co-fractionation Homo sapiens
236 RPS28 6234
Affinity Capture-MS Homo sapiens
237 RBM4 5936
Affinity Capture-MS Homo sapiens
238 PDLIM5 10611
Co-fractionation Homo sapiens
239 RPL23A 6147
Affinity Capture-MS Homo sapiens
240 DHX16 8449
Co-fractionation Homo sapiens
241 BECN1 8678
Affinity Capture-MS Homo sapiens
242 PRKCA 5578
Co-fractionation Homo sapiens
243 EIF3M 10480
Affinity Capture-MS Homo sapiens
244 RPSA 3921
Affinity Capture-MS Homo sapiens
245 EIF4B 1975
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
246 UPF1 5976
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
247 PINK1  
Affinity Capture-MS Homo sapiens
248 TRIM28 10155
Co-fractionation Homo sapiens
249 FAM50A 9130
Affinity Capture-MS Homo sapiens
250 RPL8 6132
Affinity Capture-MS Homo sapiens
251 HNRNPF 3185
Co-fractionation Homo sapiens
252 RPS27L 51065
Affinity Capture-MS Homo sapiens
253 SERBP1 26135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
254 CCT8 10694
Co-fractionation Homo sapiens
255 SNX2 6643
Co-fractionation Homo sapiens
256 KRAS 3845
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
Negative Genetic Homo sapiens
257 ARHGAP23 57636
Affinity Capture-MS Homo sapiens
258 C9orf72  
Affinity Capture-MS Homo sapiens
259 PPP2R1A 5518
Co-fractionation Homo sapiens
260 EIF3L 51386
Affinity Capture-MS Homo sapiens
261 RCOR1  
Co-fractionation Homo sapiens
262 SMS 6611
Co-fractionation Homo sapiens
263 IGF2BP2 10644
Affinity Capture-MS Homo sapiens
264 RPL17 6139
Affinity Capture-MS Homo sapiens
265 CASC3  
Affinity Capture-MS Homo sapiens
266 PSMD3 5709
Co-fractionation Homo sapiens
267 PROSER2 254427
Affinity Capture-MS Homo sapiens
268 GTF2E2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here