Gene description for CLTA
Gene name clathrin, light chain A
Gene symbol CLTA
Other names/aliases LCA
Species Homo sapiens
 Database cross references - CLTA
ExoCarta ExoCarta_1211
Vesiclepedia VP_1211
Entrez Gene 1211
HGNC 2090
MIM 118960
UniProt P09496  
 CLTA identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells Unpublished / Not applicable
Monocytic leukemia cells 34108659    
Neuroblastoma cells 25944692    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for CLTA
Molecular Function
    structural molecule activity GO:0005198 IEA
    protein binding GO:0005515 IPI
    clathrin heavy chain binding GO:0032050 IBA
    clathrin heavy chain binding GO:0032050 IPI
    peptide binding GO:0042277 IEA
    protein-containing complex binding GO:0044877 IEA
    GTPase binding GO:0051020 IEA
Biological Process
    intracellular protein transport GO:0006886 IEA
    clathrin coat assembly GO:0048268 IMP
    synaptic vesicle endocytosis GO:0048488 IEA
    cell division GO:0051301 IEA
    clathrin-dependent endocytosis GO:0072583 IBA
Subcellular Localization
    spindle GO:0005819 IEA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 TAS
    membrane GO:0016020 HDA
    clathrin coat GO:0030118 IMP
    clathrin coat GO:0030118 NAS
    clathrin vesicle coat GO:0030125 IBA
    clathrin coat of trans-Golgi network vesicle GO:0030130 IEA
    clathrin coat of coated pit GO:0030132 IEA
    synaptic vesicle membrane GO:0030672 IBA
    cytoplasmic vesicle GO:0031410 ISS
    trans-Golgi network membrane GO:0032588 TAS
    endolysosome membrane GO:0036020 TAS
    clathrin-coated endocytic vesicle GO:0045334 NAS
    clathrin complex GO:0071439 IDA
    presynaptic endocytic zone membrane GO:0098835 IEA
    postsynaptic endocytic zone cytoplasmic component GO:0099631 IBA
 Experiment description of studies that identified CLTA in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
12
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
15
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
19
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
20
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
26
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
29
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
31
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
34
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
36
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
37
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
38
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
39
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
40
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
41
Experiment ID 834
MISEV standards
✔
EM
Biophysical techniques
✔
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 835
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
44
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
45
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CLTA
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CKMT2  
Affinity Capture-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 AP2S1 1175
Affinity Capture-MS Homo sapiens
4 ACTR2 10097
Affinity Capture-MS Homo sapiens
5 RPSA 3921
Affinity Capture-MS Homo sapiens
6 C1orf198 84886
Proximity Label-MS Homo sapiens
7 ENPP4 22875
Affinity Capture-MS Homo sapiens
8 YKT6 10652
Proximity Label-MS Homo sapiens
9 BTBD6  
Affinity Capture-MS Homo sapiens
10 AP2B1 163
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 PPP1CB 5500
Affinity Capture-MS Homo sapiens
12 SIPA1L3  
Proximity Label-MS Homo sapiens
13 ARHGEF19  
Affinity Capture-MS Homo sapiens
14 TFRC 7037
Affinity Capture-MS Homo sapiens
15 Tpm1 22003
Affinity Capture-MS Mus musculus
16 MITD1 129531
Affinity Capture-MS Homo sapiens
17 HSPA6 3310
Proximity Label-MS Homo sapiens
18 AAK1 22848
Proximity Label-MS Homo sapiens
19 DCP1B  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 ALMS1  
Proximity Label-MS Homo sapiens
21 ASNA1 439
Affinity Capture-MS Homo sapiens
22 WNK1 65125
Proximity Label-MS Homo sapiens
23 CCDC91 55297
Proximity Label-MS Homo sapiens
24 FMR1 2332
Affinity Capture-MS Homo sapiens
25 BTF3 689
Affinity Capture-MS Homo sapiens
26 VPRBP 9730
Affinity Capture-MS Homo sapiens
27 FKBP15 23307
Proximity Label-MS Homo sapiens
28 Calml3  
Affinity Capture-MS Mus musculus
29 MAST4  
Proximity Label-MS Homo sapiens
30 DBN1 1627
Affinity Capture-MS Homo sapiens
31 CD2AP 23607
Affinity Capture-MS Homo sapiens
32 STON2 85439
Proximity Label-MS Homo sapiens
33 HSPA1L 3305
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 EPS15 2060
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 TXNL1 9352
Proximity Label-MS Homo sapiens
36 GRIPAP1 56850
Proximity Label-MS Homo sapiens
37 Cul3  
Affinity Capture-MS Mus musculus
38 RPL14 9045
Affinity Capture-MS Homo sapiens
39 THOC7 80145
Affinity Capture-MS Homo sapiens
40 Actb 11461
Affinity Capture-MS Mus musculus
41 CLTB 1212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 AFTPH  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 Nhsl1  
Affinity Capture-MS Mus musculus
44 FAM21C 253725
Proximity Label-MS Homo sapiens
45 KIAA1671  
Proximity Label-MS Homo sapiens
46 DNAJB6 10049
Proximity Label-MS Homo sapiens
47 MAP1LC3B 81631
Two-hybrid Homo sapiens
48 CAPZB 832
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 VTA1 51534
Affinity Capture-MS Homo sapiens
50 SART3 9733
Affinity Capture-MS Homo sapiens
51 TNRC6A 27327
Proximity Label-MS Homo sapiens
52 SPAST 6683
Affinity Capture-MS Homo sapiens
53 USO1 8615
Proximity Label-MS Homo sapiens
54 HSPA2 3306
Proximity Label-MS Homo sapiens
55 CFAP97  
Affinity Capture-MS Homo sapiens
56 PALM2-AKAP2 445815
Proximity Label-MS Homo sapiens
57 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
58 AP2A1 160
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 EPN2 22905
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 DDX6 1656
Affinity Capture-MS Homo sapiens
61 HGS 9146
Proximity Label-MS Homo sapiens
62 COPS5 10987
Affinity Capture-MS Homo sapiens
63 FBXW7  
Affinity Capture-MS Homo sapiens
64 RABL6 55684
Proximity Label-MS Homo sapiens
65 STX8 9482
Affinity Capture-MS Homo sapiens
66 IQGAP1 8826
Affinity Capture-MS Homo sapiens
67 CPSF7 79869
Affinity Capture-MS Homo sapiens
68 HSPH1 10808
Affinity Capture-MS Homo sapiens
69 AP1G1 164
Affinity Capture-MS Homo sapiens
70 AHNAK2 113146
Proximity Label-MS Homo sapiens
71 OBSL1 23363
Affinity Capture-MS Homo sapiens
72 NBR1 4077
Affinity Capture-MS Homo sapiens
73 CHMP2B 25978
Affinity Capture-MS Homo sapiens
74 MYCN  
Affinity Capture-MS Homo sapiens
75 Cenpe  
Affinity Capture-MS Mus musculus
76 EPS15L1 58513
Proximity Label-MS Homo sapiens
77 AP1AR 55435
Affinity Capture-MS Homo sapiens
78 ERP44 23071
Affinity Capture-MS Homo sapiens
79 Spast  
Affinity Capture-MS Mus musculus
80 XRN1 54464
Affinity Capture-MS Homo sapiens
81 ITGA4 3676
Affinity Capture-MS Homo sapiens
82 Cd2ap 12488
Affinity Capture-MS Mus musculus
83 DNAJC7 7266
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
84 VCAM1 7412
Affinity Capture-MS Homo sapiens
85 SORT1 6272
Affinity Capture-MS Homo sapiens
86 WDR45  
Proximity Label-MS Homo sapiens
87 RIPK2  
Proximity Label-MS Homo sapiens
88 KLHL20  
Affinity Capture-MS Homo sapiens
89 GTSE1 51512
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 NONO 4841
Affinity Capture-MS Homo sapiens
91 SEC23A 10484
Affinity Capture-MS Homo sapiens
92 ARIH2 10425
Affinity Capture-MS Homo sapiens
93 Sec24c  
Affinity Capture-MS Mus musculus
94 AP4E1  
Proximity Label-MS Homo sapiens
95 ARHGEF4  
Affinity Capture-MS Homo sapiens
96 MAD2L2 10459
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
97 Lima1  
Affinity Capture-MS Mus musculus
98 RBM8A 9939
Co-fractionation Homo sapiens
99 KIF14 9928
Affinity Capture-MS Homo sapiens
100 CBL 867
Proximity Label-MS Homo sapiens
101 HSPA8 3312
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
102 KIDINS220 57498
Affinity Capture-MS Homo sapiens
103 LSM2 57819
Affinity Capture-MS Homo sapiens
104 AP1S2 8905
Affinity Capture-MS Homo sapiens
105 HSPA9 3313
Affinity Capture-MS Homo sapiens
106 CHMP4C 92421
Affinity Capture-MS Homo sapiens
107 NOS1AP  
Proximity Label-MS Homo sapiens
108 TOLLIP 54472
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 MYO18A 399687
Affinity Capture-MS Homo sapiens
110 ENSA 2029
Proximity Label-MS Homo sapiens
111 LSM5  
Affinity Capture-MS Homo sapiens
112 RGS2  
Two-hybrid Homo sapiens
113 AGFG1 3267
Proximity Label-MS Homo sapiens
114 CAPZA1 829
Proximity Label-MS Homo sapiens
115 ZFYVE16  
Proximity Label-MS Homo sapiens
116 TMEM43 79188
Affinity Capture-MS Homo sapiens
117 L1RE1  
Affinity Capture-MS Homo sapiens
118 ALDH1A2 8854
Proximity Label-MS Homo sapiens
119 LSM7  
Affinity Capture-MS Homo sapiens
120 PNRC1 10957
Affinity Capture-MS Homo sapiens
121 CEP192 55125
Proximity Label-MS Homo sapiens
122 RABEP1 9135
Proximity Label-MS Homo sapiens
123 GGA1 26088
Proximity Label-MS Homo sapiens
124 RPL7A 6130
Affinity Capture-MS Homo sapiens
125 MAPRE1 22919
Affinity Capture-MS Homo sapiens
126 CLTCL1 8218
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
127 RAB4A 5867
Affinity Capture-MS Homo sapiens
128 HTT 3064
Co-fractionation Homo sapiens
129 ATG16L1 55054
Affinity Capture-MS Homo sapiens
130 C10orf88  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
131 ALDH18A1 5832
Affinity Capture-MS Homo sapiens
132 DNAJC5 80331
Proximity Label-MS Homo sapiens
133 CHMP4B 128866
Affinity Capture-MS Homo sapiens
134 VCL 7414
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
135 NUMB 8650
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 MYH9 4627
Affinity Capture-MS Homo sapiens
137 VCP 7415
Affinity Capture-Western Homo sapiens
138 NTRK1 4914
Affinity Capture-MS Homo sapiens
139 BTBD3  
Affinity Capture-MS Homo sapiens
140 TAB2  
Proximity Label-MS Homo sapiens
141 DCP1A 55802
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 DNAJA1 3301
Proximity Label-MS Homo sapiens
143 TMEM192 201931
Affinity Capture-MS Homo sapiens
144 PATL1 219988
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
145 BMP2K 55589
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 PIK3R1 5295
Affinity Capture-MS Homo sapiens
147 Coro1c 23790
Affinity Capture-MS Mus musculus
148 AP3B1 8546
Proximity Label-MS Homo sapiens
149 PIK3C2A 5286
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
150 STAMBP 10617
Affinity Capture-MS Homo sapiens
151 UPF1 5976
Affinity Capture-MS Homo sapiens
152 DNAJB5  
Proximity Label-MS Homo sapiens
153 PICALM 8301
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 DNTTIP2  
Affinity Capture-MS Homo sapiens
155 GAK 2580
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 MIA3 375056
Proximity Label-MS Homo sapiens
157 BAG2 9532
Affinity Capture-MS Homo sapiens
158 BAG3 9531
Proximity Label-MS Homo sapiens
159 ANLN 54443
Affinity Capture-MS Homo sapiens
160 NEDD1 121441
Proximity Label-MS Homo sapiens
161 LIMA1 51474
Affinity Capture-MS Homo sapiens
162 SYNJ1 8867
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
163 ITSN2 50618
Proximity Label-MS Homo sapiens
164 AP1M1 8907
Affinity Capture-MS Homo sapiens
165 CLINT1 9685
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 Myh9 17886
Affinity Capture-MS Mus musculus
167 ATP6AP2 10159
Affinity Capture-MS Homo sapiens
168 KIF15 56992
Proximity Label-MS Homo sapiens
169 DOCK8 81704
Affinity Capture-MS Homo sapiens
170 NBEA  
Proximity Label-MS Homo sapiens
171 SEC13 6396
Affinity Capture-MS Homo sapiens
172 YBX1 4904
Affinity Capture-MS Homo sapiens
173 OCRL 4952
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
174 LSM4 25804
Affinity Capture-MS Homo sapiens
175 HSPA4 3308
Affinity Capture-MS Homo sapiens
176 CTNNB1 1499
Affinity Capture-MS Homo sapiens
177 C1orf226  
Proximity Label-MS Homo sapiens
178 FAM134A 79137
Affinity Capture-MS Homo sapiens
179 NUP88 4927
Proximity Label-MS Homo sapiens
180 VAMP3 9341
Affinity Capture-MS Homo sapiens
181 CUL3 8452
Affinity Capture-MS Homo sapiens
182 NR3C1 2908
Proximity Label-MS Homo sapiens
183 PDLIM7 9260
Affinity Capture-MS Homo sapiens
184 EGFR 1956
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
185 MYO19  
Affinity Capture-MS Homo sapiens
186 HSP90AB3P 3327
Affinity Capture-MS Homo sapiens
187 STAU1 6780
Affinity Capture-MS Homo sapiens
188 PYCR2 29920
Affinity Capture-MS Homo sapiens
189 HIP1R 9026
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
190 TFG 10342
Affinity Capture-MS Homo sapiens
191 GGA3 23163
Proximity Label-MS Homo sapiens
192 ELMSAN1  
Affinity Capture-MS Homo sapiens
193 SCYL2 55681
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
194 SMAP1 60682
Proximity Label-MS Homo sapiens
195 CDK2 1017
Affinity Capture-MS Homo sapiens
196 RPL36 25873
Affinity Capture-MS Homo sapiens
197 SYNPO 11346
Affinity Capture-MS Homo sapiens
198 MYC  
Affinity Capture-MS Homo sapiens
199 Uso1 56041
Affinity Capture-MS Mus musculus
200 HEATR5B 54497
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 FN3KRP 79672
Affinity Capture-MS Homo sapiens
202 ZNF692  
Affinity Capture-MS Homo sapiens
203 SEC16A 9919
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
204 EPN1 29924
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
205 AP2A2 161
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
206 SMAP2 64744
Proximity Label-MS Homo sapiens
207 HSPA1A 3303
Proximity Label-MS Homo sapiens
208 SH3D19 152503
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 TCP11L2  
Affinity Capture-MS Homo sapiens
210 EIF3CL 728689
Affinity Capture-MS Homo sapiens
211 RABGAP1L 9910
Proximity Label-MS Homo sapiens
212 HIP1 3092
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 PTPN23 25930
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
214 DAB2 1601
Proximity Label-MS Homo sapiens
215 AP2M1 1173
Affinity Capture-MS Homo sapiens
216 VAMP4 8674
Affinity Capture-MS Homo sapiens
217 CLTC 1213
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
218 STX10 8677
Affinity Capture-MS Homo sapiens
219 CEBPA  
Protein-peptide Homo sapiens
220 NUMBL 9253
Proximity Label-MS Homo sapiens
221 Ppp1cb 19046
Affinity Capture-MS Mus musculus
222 LSM1 27257
Affinity Capture-MS Homo sapiens
223 TNRC6B  
Proximity Label-MS Homo sapiens
224 MAP7D2 256714
Affinity Capture-MS Homo sapiens
225 AP1S1 1174
Affinity Capture-MS Homo sapiens
226 DNAJC6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
227 C10orf2 56652
Affinity Capture-MS Homo sapiens
228 FXR1 8087
Affinity Capture-MS Homo sapiens
229 SEC24B 10427
Affinity Capture-MS Homo sapiens
230 STX12 23673
Affinity Capture-MS Homo sapiens
231 SYNRG 11276
Proximity Label-MS Homo sapiens
232 RPS14 6208
Affinity Capture-MS Homo sapiens
233 NES 10763
Affinity Capture-MS Homo sapiens
234 TES 26136
Proximity Label-MS Homo sapiens
235 FN1 2335
Affinity Capture-MS Homo sapiens
236 TNK2 10188
Affinity Capture-Western Homo sapiens
237 RPS27A 6233
Affinity Capture-MS Homo sapiens
238 ARRB2 409
Affinity Capture-MS Homo sapiens
239 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
240 KIAA0430  
Affinity Capture-MS Homo sapiens
241 Tmod3 50875
Affinity Capture-MS Mus musculus
242 PSMD1 5707
Proximity Label-MS Homo sapiens
243 APPL1 26060
Affinity Capture-MS Homo sapiens
244 ITSN1 6453
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
245 RPS3 6188
Affinity Capture-MS Homo sapiens
246 NUP133 55746
Affinity Capture-MS Homo sapiens
247 ANKHD1-EIF4EBP3  
Proximity Label-MS Homo sapiens
248 TP53 7157
Affinity Capture-MS Homo sapiens
249 PSAT1 29968
Affinity Capture-MS Homo sapiens
250 TMED5 50999
Affinity Capture-MS Homo sapiens
251 VPS33A 65082
Co-fractionation Homo sapiens
252 EEA1 8411
Affinity Capture-MS Homo sapiens
253 DENND1A 57706
Proximity Label-MS Homo sapiens
254 DNAJA2 10294
Proximity Label-MS Homo sapiens
255 LONP1 9361
Proximity Label-MS Homo sapiens
256 MKL2  
Affinity Capture-MS Homo sapiens
257 CENPJ 55835
Affinity Capture-MS Homo sapiens
258 SEC23B 10483
Affinity Capture-MS Homo sapiens
259 NANP 140838
Proximity Label-MS Homo sapiens
260 Myo1c 17913
Affinity Capture-MS Mus musculus
261 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
262 KIAA1804  
Affinity Capture-MS Homo sapiens
263 CAPZA2 830
Affinity Capture-MS Homo sapiens
264 RPS27 6232
Affinity Capture-MS Homo sapiens
265 NSDHL 50814
Affinity Capture-MS Homo sapiens
266 ARHGAP18 93663
Affinity Capture-MS Homo sapiens
267 SYNJ2 8871
Proximity Label-MS Homo sapiens
268 TNRC6C  
Proximity Label-MS Homo sapiens
269 TTK 7272
Proximity Label-MS Homo sapiens
270 EDC3 80153
Affinity Capture-MS Homo sapiens
271 DNMBP 23268
Proximity Label-MS Homo sapiens
272 Smap1  
Affinity Capture-MS Mus musculus
273 DCP2  
Affinity Capture-MS Homo sapiens
274 Myh10 77579
Affinity Capture-MS Mus musculus
275 RPS26 6231
Affinity Capture-MS Homo sapiens
276 ARFRP1 10139
Affinity Capture-MS Homo sapiens
277 Arhgap6  
Affinity Capture-MS Mus musculus
278 MAP1LC3A 84557
Affinity Capture-MS Homo sapiens
279 EDC4 23644
Affinity Capture-MS Homo sapiens
280 WNK3  
Proximity Label-MS Homo sapiens
281 MOV10 4343
Affinity Capture-MS Homo sapiens
282 HNRNPL 3191
Affinity Capture-MS Homo sapiens
283 REPS1 85021
Affinity Capture-MS Homo sapiens
284 IST1 9798
Affinity Capture-MS Homo sapiens
285 ARRB1 408
Affinity Capture-MS Homo sapiens
286 YTHDC2 64848
Affinity Capture-MS Homo sapiens
287 FLNA 2316
Affinity Capture-MS Homo sapiens
288 CHMP2A 27243
Affinity Capture-MS Homo sapiens
289 TMEM38B  
Affinity Capture-MS Homo sapiens
290 CIT 11113
Affinity Capture-MS Homo sapiens
291 IGF2R 3482
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
292 SERBP1 26135
Affinity Capture-MS Homo sapiens
293 LSM6 11157
Affinity Capture-MS Homo sapiens
294 GGA2 23062
Proximity Label-MS Homo sapiens
295 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
296 Ptpn23 104831
Affinity Capture-MS Mus musculus
297 WNK2  
Proximity Label-MS Homo sapiens
298 TRIM29 23650
Affinity Capture-MS Homo sapiens
299 BCR 613
Proximity Label-MS Homo sapiens
300 AP3D1 8943
Proximity Label-MS Homo sapiens
301 LSM14A 26065
Affinity Capture-MS Homo sapiens
302 FCHO2 115548
Proximity Label-MS Homo sapiens
303 ARX  
Affinity Capture-MS Homo sapiens
304 HSPA1B 3304
Affinity Capture-MS Homo sapiens
305 IGF2BP2 10644
Affinity Capture-MS Homo sapiens
306 CHMP5 51510
Affinity Capture-MS Homo sapiens
307 CC2D1A 54862
Proximity Label-MS Homo sapiens
308 AP1B1 162
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
309 DYRK1A 1859
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CLTA is involved
PathwayEvidenceSource
Adaptive Immune System TAS Reactome
Axon guidance TAS Reactome
Axon guidance IEA Reactome
Beta-catenin independent WNT signaling TAS Reactome
Cargo recognition for clathrin-mediated endocytosis TAS Reactome
Clathrin-mediated endocytosis TAS Reactome
Developmental Biology TAS Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
Entry of Influenza Virion into Host Cell via Endocytosis TAS Reactome
EPH-ephrin mediated repulsion of cells TAS Reactome
EPH-Ephrin signaling TAS Reactome
Formation of annular gap junctions TAS Reactome
Gap junction degradation TAS Reactome
Gap junction trafficking TAS Reactome
Gap junction trafficking and regulation TAS Reactome
Golgi Associated Vesicle Biogenesis TAS Reactome
Immune System TAS Reactome
Infectious disease TAS Reactome
Influenza Infection TAS Reactome
L1CAM interactions TAS Reactome
L1CAM interactions IEA Reactome
LDL clearance TAS Reactome
Lysosome Vesicle Biogenesis TAS Reactome
Membrane Trafficking TAS Reactome
MHC class II antigen presentation TAS Reactome
Nervous system development TAS Reactome
Nervous system development IEA Reactome
PCP/CE pathway TAS Reactome
Plasma lipoprotein assembly, remodeling, and clearance TAS Reactome
Plasma lipoprotein clearance TAS Reactome
Recycling pathway of L1 TAS Reactome
Recycling pathway of L1 IEA Reactome
Retrograde neurotrophin signalling IEA Reactome
Retrograde neurotrophin signalling TAS Reactome
Signal Transduction TAS Reactome
Signal Transduction IEA Reactome
Signaling by NTRK1 (TRKA) IEA Reactome
Signaling by NTRK1 (TRKA) TAS Reactome
Signaling by NTRKs IEA Reactome
Signaling by NTRKs TAS Reactome
Signaling by Receptor Tyrosine Kinases IEA Reactome
Signaling by Receptor Tyrosine Kinases TAS Reactome
Signaling by WNT TAS Reactome
trans-Golgi Network Vesicle Budding TAS Reactome
Transport of small molecules TAS Reactome
Vesicle-mediated transport TAS Reactome
Viral Infection Pathways TAS Reactome
VLDLR internalisation and degradation TAS Reactome
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 TAS Reactome
WNT5A-dependent internalization of FZD4 TAS Reactome





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