Experiment description of studies that identified MAZ in sEVs

1 Experiment ID 235 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name HKCI-8 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

Protein-protein interactions for MAZ

Protein Interactor ExoCarta ID Identification method PubMed Species 1 RBPMS 11030 Two-hybrid Homo sapiens 2 UBE2H 7328 Affinity Capture-MS Homo sapiens 3 CDC14B 8555 Proximity Label-MS Homo sapiens 4 MECP2 4204 Affinity Capture-MS Homo sapiens 5 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 6 MYCN   Affinity Capture-MS Homo sapiens 7 KLF15   Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens 8 ARHGEF19   Affinity Capture-MS Homo sapiens 9 UBE2O 63893 Affinity Capture-MS Homo sapiens 10 CENPA   Proximity Label-MS Homo sapiens 11 FBXL6   Affinity Capture-MS Homo sapiens 12 NOTCH2 4853 Affinity Capture-MS Homo sapiens 13 Arhgap1 228359 Affinity Capture-MS Mus musculus 14 RC3H2   Affinity Capture-MS Homo sapiens 15 KDM4D   Affinity Capture-MS Homo sapiens 16 APEX1 328 Proximity Label-MS Homo sapiens 17 HIST1H2BG 8339 Proximity Label-MS Homo sapiens 18 KEAP1 9817 Affinity Capture-MS Homo sapiens 19 DMRTB1   Two-hybrid Homo sapiens 20 KLF8   Affinity Capture-MS Homo sapiens 21 CUL3 8452 Affinity Capture-MS Homo sapiens 22 HIST1H4A 8359 Affinity Capture-MS Homo sapiens 23 FOS 2353 Far Western Homo sapiens Affinity Capture-Western Homo sapiens 24 Sf3a3 75062 Two-hybrid Mus musculus 25 CSNK2A1 1457 Biochemical Activity Homo sapiens 26 PARK2   Affinity Capture-MS Homo sapiens 27 OTUB1 55611 Affinity Capture-MS Homo sapiens 28 Nudt21 68219 Two-hybrid Mus musculus 29 APOD 347 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 30 NXF1 10482 Affinity Capture-RNA Homo sapiens 31 UFL1 23376 Affinity Capture-MS Homo sapiens 32 JUN 3725 Far Western Homo sapiens Affinity Capture-Western Homo sapiens 33 MOV10 4343 Affinity Capture-RNA Homo sapiens 34 MYC   Affinity Capture-MS Homo sapiens 35 HECW2   Affinity Capture-MS Homo sapiens 36 OGT 8473 Reconstituted Complex Homo sapiens 37 AIM2   Affinity Capture-MS Homo sapiens 38 TRIM31   Affinity Capture-MS Homo sapiens 39 BPTF 2186 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 40 EHMT2 10919 Two-hybrid Homo sapiens 41 TOLLIP 54472 Proximity Label-MS Homo sapiens 42 DCC   Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Two-hybrid Homo sapiens 43 BRD1 23774 Affinity Capture-MS Homo sapiens 44 SERBP1 26135 Affinity Capture-MS Homo sapiens 45 DDRGK1 65992 Affinity Capture-MS Homo sapiens 46 MAPK14 1432 Affinity Capture-MS Homo sapiens 47 RC3H1 149041 Affinity Capture-MS Homo sapiens 48 TIAM1   Affinity Capture-MS Homo sapiens 49 RPA3 6119 Proximity Label-MS Homo sapiens 50 KRT31 3881 Two-hybrid Homo sapiens 51 TEAD1   Proximity Label-MS Homo sapiens 52 Cpsf6   Two-hybrid Mus musculus 53 KLF5   Affinity Capture-MS Homo sapiens 54 EP300 2033 Affinity Capture-MS Homo sapiens 55 KRTAP10-9   Two-hybrid Homo sapiens View the network

Pathways in which MAZ is involved

No pathways found