Gene description for HGF
Gene name	hepatocyte growth factor (hepapoietin A; scatter factor)
Gene symbol	HGF
Other names/aliases	DFNB39 F-TCF HGFB HPTA SF
Species	Homo sapiens
Database cross references - HGF
ExoCarta	ExoCarta_3082
Vesiclepedia	VP_3082
Entrez Gene	3082
HGNC	4893
MIM	142409
UniProt	P14210
HGF identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for HGF

Molecular Function     endopeptidase activity GO:0004175 IBA     serine-type endopeptidase activity GO:0004252 NAS     signaling receptor binding GO:0005102 IBA     protein binding GO:0005515 IPI     growth factor activity GO:0008083 NAS     chemoattractant activity GO:0042056 IDA     identical protein binding GO:0042802 IPI Biological Process     mitotic cell cycle GO:0000278 NAS     cell morphogenesis GO:0000902 IEA     epithelial to mesenchymal transition GO:0001837 TAS     liver development GO:0001889 IEA     proteolysis GO:0006508 NAS     negative regulation of autophagy GO:0010507 NAS     skeletal muscle cell proliferation GO:0014856 IEA     positive regulation of cell migration GO:0030335 IDA     negative regulation of interleukin-6 production GO:0032715 IEA     positive regulation of interleukin-10 production GO:0032733 IEA     cellular response to hepatocyte growth factor stimulus GO:0035729 IDA     negative regulation of apoptotic process GO:0043066 IBA     positive regulation of MAPK cascade GO:0043410 IDA     positive regulation of osteoblast differentiation GO:0045669 NAS     positive regulation of transcription by RNA polymerase II GO:0045944 NAS     hepatocyte growth factor receptor signaling pathway GO:0048012 IBA     hepatocyte growth factor receptor signaling pathway GO:0048012 IDA     epithelial cell proliferation GO:0050673 IEA     negative regulation of inflammatory response GO:0050728 IEA     positive chemotaxis GO:0050918 IEA     myoblast proliferation GO:0051450 IEA     positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 IDA     cell chemotaxis GO:0060326 IDA     regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling GO:0060665 IDA     negative regulation of release of cytochrome c from mitochondria GO:0090201 IDA     regulation of p38MAPK cascade GO:1900744 IEA     negative regulation of hydrogen peroxide-mediated programmed cell death GO:1901299 IDA     negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 IEA     positive regulation of DNA biosynthetic process GO:2000573 IDA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IBA     membrane GO:0016020 HDA     platelet alpha granule lumen GO:0031093 TAS