Experiment description of studies that identified PSD3 in sEVs

1 Experiment ID 488 MISEV standards ✔ EM Biophysical techniques ✔ CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 36408942     Organism Homo sapiens Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ." Journal name Proteomics Publication year 2023 Sample Mesenchymal stem cells Sample name UCMSC Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectometry

2 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

3 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for PSD3

Protein Interactor ExoCarta ID Identification method PubMed Species 1 YWHAH 7533 Affinity Capture-MS Homo sapiens 2 PMS2   Affinity Capture-MS Homo sapiens 3 PTPRG 5793 Proximity Label-MS Homo sapiens 4 RAB35 11021 Proximity Label-MS Homo sapiens 5 NPAS1   Affinity Capture-MS Homo sapiens 6 TP53 7157 Synthetic Growth Defect Homo sapiens 7 OCLN 100506658 Proximity Label-MS Homo sapiens 8 LAMTOR1 55004 Proximity Label-MS Homo sapiens 9 MARCKS 4082 Proximity Label-MS Homo sapiens 10 LAMP3   Proximity Label-MS Homo sapiens 11 YWHAZ 7534 Affinity Capture-MS Homo sapiens 12 GJA1 2697 Proximity Label-MS Homo sapiens 13 EPB41L4A 64097 Proximity Label-MS Homo sapiens 14 LAMP1 3916 Proximity Label-MS Homo sapiens 15 PTPRA 5786 Proximity Label-MS Homo sapiens 16 LCK 3932 Proximity Label-MS Homo sapiens 17 MX1 4599 Two-hybrid Homo sapiens 18 COPB2 9276 Affinity Capture-MS Homo sapiens 19 MLH1 4292 Affinity Capture-MS Homo sapiens 20 ARF6 382 Proximity Label-MS Homo sapiens 21 CXADR 1525 Proximity Label-MS Homo sapiens 22 COPA 1314 Affinity Capture-MS Homo sapiens 23 C11orf52 91894 Proximity Label-MS Homo sapiens 24 LYN 4067 Proximity Label-MS Homo sapiens 25 MCAM 4162 Proximity Label-MS Homo sapiens 26 DNAJC5 80331 Proximity Label-MS Homo sapiens 27 RAB2A 5862 Proximity Label-MS Homo sapiens 28 DIRAS3   Proximity Label-MS Homo sapiens 29 METTL21B   Affinity Capture-MS Homo sapiens 30 EPHA2 1969 Proximity Label-MS Homo sapiens 31 KRAS 3845 Proximity Label-MS Homo sapiens 32 RHOB 388 Proximity Label-MS Homo sapiens 33 CAV1 857 Proximity Label-MS Homo sapiens 34 CTDSPL 10217 Proximity Label-MS Homo sapiens 35 FLOT1 10211 Proximity Label-MS Homo sapiens 36 ARAP1 116985 Two-hybrid Homo sapiens View the network

Pathways in which PSD3 is involved

No pathways found