Gene description for SWAP70
Gene name SWAP switching B-cell complex 70kDa subunit
Gene symbol SWAP70
Other names/aliases HSPC321
Species Homo sapiens
 Database cross references - SWAP70
ExoCarta ExoCarta_23075
Entrez Gene 23075
HGNC 17070
MIM 604762
UniProt Q9UH65  
 SWAP70 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for SWAP70
Molecular Function
    ATP binding GO:0005524 IEA
    protein binding GO:0005515 IPI
    DNA binding GO:0003677 IEA
    calcium ion binding GO:0005509 IEA
Biological Process
    isotype switching GO:0045190 IEA
Subcellular Localization
    nucleus GO:0005634 IEA
    plasma membrane GO:0005886 IEA
    lamellipodium GO:0030027 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified SWAP70 in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SWAP70
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 NCL 4691
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
2 PARP1 142
Co-purification Homo sapiens
3 PARP3 10039
Affinity Capture-MS Homo sapiens
4 IGHG1 3500
Invitro Homo sapiens
Affinity Capture-MS Homo sapiens
5 NPM1 4869
Affinity Capture-MS Homo sapiens
Co-purification Homo sapiens
View the network image/svg+xml
 Pathways in which SWAP70 is involved
No pathways found

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