Gene description for ZBTB49
Gene name zinc finger and BTB domain containing 49
Gene symbol ZBTB49
Other names/aliases ZNF509
Species Homo sapiens
 Database cross references - ZBTB49
ExoCarta ExoCarta_166793
Entrez Gene 166793
HGNC 19883
MIM 616238
UniProt Q6ZSB9  
 ZBTB49 identified in exosomes derived from the following tissue/cell type
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for ZBTB49
Molecular Function
    metal ion binding GO:0046872 IEA
    transcription coactivator binding GO:0001223 IPI
    sequence-specific DNA binding RNA polymerase II transcription factor activity GO:0000981 IBA
    sequence-specific DNA binding GO:0043565 IDA
    RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 IBA
    transcription factor binding GO:0008134 IPI
Biological Process
    cell cycle arrest GO:0007050 IDA
    positive regulation of transcription from RNA polymerase II promoter GO:0045944 IDA
    transcription from RNA polymerase II promoter GO:0006366 IBA
    negative regulation of cell proliferation GO:0008285 IDA
Subcellular Localization
    cytoplasm GO:0005737 IDA
    nucleus GO:0005634 IDA
 Experiment description of studies that identified ZBTB49 in exosomes
1
Experiment ID 196
ISEV standards
EM
EV Biophysical techniques
Alix|TSG101|HSP70
EV Cytosolic markers
CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 197
ISEV standards
EM
EV Biophysical techniques
Alix|TSG101|HSP70
EV Cytosolic markers
CD9
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors Raj DA, Fiume I, Capasso G, Pocsfalvi G.
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ZBTB49
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which ZBTB49 is involved
No pathways found





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