Experiment description of studies that identified CPLX2 in sEVs

1 Experiment ID 236 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocellular carcinoma cells Sample name MHCC97L Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RT-PCR RNA Sequencing

2 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for CPLX2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 APP 351 Reconstituted Complex Homo sapiens 2 ANKRD13C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 PPFIBP1 8496 Affinity Capture-MS Homo sapiens 4 C12orf10 60314 Two-hybrid Homo sapiens 5 ZGPAT   Affinity Capture-MS Homo sapiens 6 DBN1 1627 Cross-Linking-MS (XL-MS) Homo sapiens 7 NDRG4 65009 Two-hybrid Homo sapiens 8 FAM21A 387680 Affinity Capture-MS Homo sapiens 9 TSFM 10102 Two-hybrid Homo sapiens 10 STX1A 6804 Affinity Capture-Western Homo sapiens 11 INF2 64423 Affinity Capture-MS Homo sapiens 12 PBX3   Two-hybrid Homo sapiens 13 SRP54 6729 Affinity Capture-MS Homo sapiens 14 PHF6   Affinity Capture-MS Homo sapiens 15 PRNP 5621 Affinity Capture-MS Homo sapiens 16 DHX16 8449 Affinity Capture-MS Homo sapiens 17 SCCPDH 51097 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 CPLX1 10815 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 RAP1A 5906 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 DEGS1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens View the network

Pathways in which CPLX2 is involved

No pathways found