Gene ontology annotations for C12orf10
Experiment description of studies that identified C12orf10 in exosomes
1
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
5
Experiment ID
207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DKO-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
6
Experiment ID
208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
Dks-8
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
7
Experiment ID
209
MISEV standards
✘
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23161513
Organism
Homo sapiens
Experiment description
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors
"Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name
Mol Cell Proteomics
Publication year
2012
Sample
Colorectal cancer cells
Sample name
DLD-1
Isolation/purification methods
Differential centrifugation Filtration
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
8
Experiment ID
239
MISEV standards
✘
Biophysical techniques
✔
Alix|TSG101|CD9
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
26022510
Organism
Homo sapiens
Experiment description
Serum-free culture alters the quantity and protein composition of neuroblastoma-derived extracellular vesicles
Authors
"Li J, Lee Y, Johansson HJ, Mager I, Vader P, Nordin JZ, Wiklander OP, Lehtio J, Wood MJ6, Andaloussi SE."
Journal name
J Extracell Vesicles
Publication year
2015
Sample
Neuroblastoma cells
Sample name
N2a OptiMEM - Rep 1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
1.10-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
9
Experiment ID
242
MISEV standards
✘
Biophysical techniques
✔
Alix|TSG101
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Western blotting
PubMed ID
26022510
Organism
Homo sapiens
Experiment description
Serum-free culture alters the quantity and protein composition of neuroblastoma-derived extracellular vesicles
Authors
"Li J, Lee Y, Johansson HJ, Mager I, Vader P, Nordin JZ, Wiklander OP, Lehtio J, Wood MJ6, Andaloussi SE."
Journal name
J Extracell Vesicles
Publication year
2015
Sample
Neuroblastoma cells
Sample name
N2a Pre-spun - Rep 1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
1.10-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
10
Experiment ID
191
MISEV standards
✘
Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
20124223
Organism
Homo sapiens
Experiment description
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors
"Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name
Mol Cell Proteomics
Publication year
2010
Sample
Squamous carcinoma cells
Sample name
Squamous carcinoma cell (A431)
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for C12orf10
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
SFT2D1
113402
Two-hybrid
Homo sapiens
2
HORMAD1
Two-hybrid
Homo sapiens
3
AHSA1
10598
Co-fractionation
Homo sapiens
4
TMEM239
Two-hybrid
Homo sapiens
5
NOTCH2NL
388677
Affinity Capture-MS
Homo sapiens
6
CDS2
8760
Two-hybrid
Homo sapiens
7
ALDH7A1
501
Two-hybrid
Homo sapiens
8
OXCT1
5019
Co-fractionation
Homo sapiens
9
GALT
2592
Affinity Capture-MS
Homo sapiens
10
IDH1
3417
Co-fractionation
Homo sapiens
11
GRB2
2885
Two-hybrid
Homo sapiens
12
DCAF10
Affinity Capture-MS
Homo sapiens
13
SLC17A9
Two-hybrid
Homo sapiens
14
HSPA8
3312
Co-fractionation
Homo sapiens
15
WWOX
51741
Two-hybrid
Homo sapiens
16
SUGT1
10910
Co-fractionation
Homo sapiens
17
UBQLN2
29978
Co-fractionation
Homo sapiens
18
SYP
Two-hybrid
Homo sapiens
19
FAM9B
Two-hybrid
Homo sapiens
20
RBBP7
5931
Co-fractionation
Homo sapiens
21
METTL9
51108
Two-hybrid
Homo sapiens
22
UBQLN1
29979
Co-fractionation
Homo sapiens
23
DESI2
Two-hybrid
Homo sapiens
24
HSP90AB1
3326
Affinity Capture-MS
Homo sapiens
25
HSPB1
3315
Two-hybrid
Homo sapiens
26
ELAC2
60528
Co-fractionation
Homo sapiens
27
GADD45GIP1
Two-hybrid
Homo sapiens
28
HSP90AA1
3320
Affinity Capture-MS
Homo sapiens
29
ARL6IP1
23204
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
30
MAN1C1
57134
Two-hybrid
Homo sapiens
31
DDX58
23586
Affinity Capture-RNA
Homo sapiens
32
APOA5
116519
Two-hybrid
Homo sapiens
33
AGTRAP
57085
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
34
DDX39A
10212
Co-fractionation
Homo sapiens
35
CPLX2
10814
Two-hybrid
Homo sapiens
36
BSND
Two-hybrid
Homo sapiens
37
TMEM229B
Two-hybrid
Homo sapiens
38
RPA3
6119
Proximity Label-MS
Homo sapiens
39
CMTM5
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
40
PLIN3
10226
Two-hybrid
Homo sapiens
41
COPS5
10987
Two-hybrid
Homo sapiens
42
DPH5
51611
Co-fractionation
Homo sapiens
43
DSTN
11034
Co-fractionation
Homo sapiens
44
GLRX3
10539
Co-fractionation
Homo sapiens
45
RXRB
6257
Two-hybrid
Homo sapiens
46
MMAB
326625
Affinity Capture-MS
Homo sapiens
47
HIBCH
26275
Co-fractionation
Homo sapiens
48
DNAJC17
Co-fractionation
Homo sapiens
49
TMEM56
Two-hybrid
Homo sapiens
50
DDIT4L
Two-hybrid
Homo sapiens
51
TKFC
26007
Co-fractionation
Homo sapiens
52
HSPD1
3329
Co-fractionation
Homo sapiens
53
SORD
6652
Co-fractionation
Homo sapiens
54
DGAT2L6
Two-hybrid
Homo sapiens
55
DDX39B
7919
Co-fractionation
Homo sapiens
56
YIF1A
10897
Two-hybrid
Homo sapiens
57
LHPP
64077
Affinity Capture-MS
Homo sapiens
58
PGD
5226
Co-fractionation
Homo sapiens
59
XPNPEP1
7511
Co-fractionation
Homo sapiens
60
THOP1
7064
Co-fractionation
Homo sapiens
View the network
image/svg+xml
Pathways in which C12orf10 is involved
No pathways found