Gene description for SRSF6
Gene name serine/arginine-rich splicing factor 6
Gene symbol SRSF6
Other names/aliases B52
HEL-S-91
SFRS6
SRP55
Species Homo sapiens
 Database cross references - SRSF6
ExoCarta ExoCarta_6431
Vesiclepedia VP_6431
Entrez Gene 6431
HGNC 10788
MIM 601944
UniProt Q13247  
 SRSF6 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Endothelial cells 26027894    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for SRSF6
Molecular Function
    RNA binding GO:0003723 HDA
    RNA binding GO:0003723 IBA
    RNA binding GO:0003723 IDA
    protein binding GO:0005515 IPI
    pre-mRNA binding GO:0036002 IDA
Biological Process
    alternative mRNA splicing, via spliceosome GO:0000380 IDA
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 IDA
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 IMP
    mRNA splicing, via spliceosome GO:0000398 IBA
    mRNA splice site recognition GO:0006376 IMP
    regulation of keratinocyte proliferation GO:0010837 IMP
    response to insulin GO:0032868 IEA
    negative regulation of keratinocyte differentiation GO:0045617 IMP
    negative regulation of mRNA splicing, via spliceosome GO:0048025 IDA
    positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 IDA
    regulation of wound healing GO:0061041 IMP
    negative regulation of type B pancreatic cell apoptotic process GO:2000675 IEA
Subcellular Localization
    nucleoplasm GO:0005654 TAS
    nuclear speck GO:0016607 IBA
    nuclear speck GO:0016607 IDA
 Experiment description of studies that identified SRSF6 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 226
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD9|FLOT1
Enriched markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
✘ Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
17
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
21
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for SRSF6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TRMT1L 81627
Affinity Capture-MS Homo sapiens
2 ZBTB11  
Affinity Capture-MS Homo sapiens
3 AATF  
Affinity Capture-MS Homo sapiens
4 SRPK2 6733
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 MRPS27 23107
Affinity Capture-MS Homo sapiens
6 NMNAT1  
Affinity Capture-MS Homo sapiens
7 KIF20A 10112
Affinity Capture-MS Homo sapiens
8 UTP3 57050
Affinity Capture-MS Homo sapiens
9 MRPS18C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 NOL8  
Affinity Capture-MS Homo sapiens
11 DDX23 9416
Proximity Label-MS Homo sapiens
12 WHSC1 7468
Affinity Capture-MS Homo sapiens
13 KIF23 9493
Affinity Capture-MS Homo sapiens
14 SF3B1 23451
Affinity Capture-MS Homo sapiens
15 AI837181  
Affinity Capture-MS Mus musculus
16 RPS9 6203
Affinity Capture-MS Homo sapiens
17 RPF2 84154
Affinity Capture-MS Homo sapiens
18 PTCD1 26024
Affinity Capture-MS Homo sapiens
19 MECP2 4204
Affinity Capture-MS Homo sapiens
20 SREK1 140890
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 RPL19 6143
Affinity Capture-MS Homo sapiens
22 KIF14 9928
Affinity Capture-MS Homo sapiens
23 RBMX 27316
Affinity Capture-MS Homo sapiens
24 TFB1M  
Affinity Capture-MS Homo sapiens
25 HEXIM1 10614
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
26 CHMP4C 92421
Affinity Capture-MS Homo sapiens
27 MEPCE 56257
Affinity Capture-MS Homo sapiens
28 TARBP2  
Affinity Capture-MS Homo sapiens
29 HIST1H2AG 8969
Affinity Capture-MS Homo sapiens
30 SRSF3 6428
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 YBX2 51087
Affinity Capture-MS Homo sapiens
32 RBM7  
Affinity Capture-MS Homo sapiens
33 RPL18A 6142
Affinity Capture-MS Homo sapiens
34 SRBD1  
Affinity Capture-MS Homo sapiens
35 OGT 8473
Reconstituted Complex Homo sapiens
36 RPL31 6160
Affinity Capture-MS Homo sapiens
37 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
38 CUL2 8453
Affinity Capture-MS Homo sapiens
39 RRP1B 23076
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 SRPK3  
Affinity Capture-MS Homo sapiens
41 SON 6651
Affinity Capture-MS Homo sapiens
42 RPS26P11  
Affinity Capture-MS Homo sapiens
43 GTPBP4 23560
Affinity Capture-MS Homo sapiens
44 SRPK1 6732
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
45 CCDC12  
Affinity Capture-MS Homo sapiens
46 ANLN 54443
Affinity Capture-MS Homo sapiens
47 TMPO 7112
Affinity Capture-MS Homo sapiens
48 RBM39 9584
Affinity Capture-MS Homo sapiens
49 ABT1 29777
Affinity Capture-MS Homo sapiens
50 DAP3 7818
Affinity Capture-MS Homo sapiens
51 LMNB1 4001
Co-fractionation Homo sapiens
52 SRSF4 6429
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
53 CUL3 8452
Affinity Capture-MS Homo sapiens
54 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
55 PAPD5 64282
Affinity Capture-MS Homo sapiens
56 NOM1  
Affinity Capture-MS Homo sapiens
57 RPL7L1 285855
Affinity Capture-MS Homo sapiens
58 ZC3H11A  
Affinity Capture-MS Homo sapiens
59 RBBP4 5928
Co-fractionation Homo sapiens
60 NIP7 51388
Affinity Capture-MS Homo sapiens
61 MRPL47 57129
Affinity Capture-MS Homo sapiens
62 YTHDC1  
Affinity Capture-MS Homo sapiens
63 ZNF512  
Affinity Capture-MS Homo sapiens
64 PCBP1 5093
Affinity Capture-MS Homo sapiens
65 APOBEC3F 200316
Affinity Capture-MS Homo sapiens
66 SPEN 23013
Affinity Capture-MS Homo sapiens
67 LTV1  
Affinity Capture-MS Homo sapiens
68 PATZ1  
Affinity Capture-MS Homo sapiens
69 ZFP62  
Affinity Capture-MS Homo sapiens
70 GNL3 26354
Affinity Capture-MS Homo sapiens
71 DDX55  
Affinity Capture-MS Homo sapiens
72 NGDN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 RPS16 6217
Affinity Capture-MS Homo sapiens
74 U2SURP 23350
Affinity Capture-MS Homo sapiens
75 PAXBP1  
Affinity Capture-MS Homo sapiens
76 YBX1 4904
Affinity Capture-MS Homo sapiens
77 RPS27A 6233
Affinity Capture-MS Homo sapiens
78 PRDM10  
Affinity Capture-MS Homo sapiens
79 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 EIF3I 8668
Co-fractionation Homo sapiens
81 TCERG1 10915
Cross-Linking-MS (XL-MS) Homo sapiens
82 APOBEC3D  
Affinity Capture-MS Homo sapiens
83 SRSF9 8683
Co-fractionation Homo sapiens
84 SRSF12  
Affinity Capture-MS Homo sapiens
85 TRA2B 6434
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
86 CENPU  
Affinity Capture-MS Homo sapiens
87 H2AFY 9555
Affinity Capture-MS Homo sapiens
88 KRR1 11103
Affinity Capture-MS Homo sapiens
89 LARP7 51574
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 HNRNPL 3191
Affinity Capture-MS Homo sapiens
91 ZNF768 79724
Affinity Capture-MS Homo sapiens
92 DAXX  
Affinity Capture-MS Homo sapiens
93 EP300 2033
Affinity Capture-MS Homo sapiens
94 CUL7 9820
Affinity Capture-MS Homo sapiens
95 CRNKL1 51340
Affinity Capture-MS Homo sapiens
96 PURA 5813
Affinity Capture-MS Homo sapiens
97 MRPL28 10573
Affinity Capture-MS Homo sapiens
98 NOP10 55505
Affinity Capture-MS Homo sapiens
99 NVL  
Affinity Capture-MS Homo sapiens
100 IMP4  
Affinity Capture-MS Homo sapiens
101 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
102 RBMXL1  
Affinity Capture-MS Homo sapiens
103 LUZP4  
Affinity Capture-MS Homo sapiens
104 RBM22 55696
Affinity Capture-MS Homo sapiens
105 KIAA0020 9933
Affinity Capture-MS Homo sapiens
106 RPS17 6218
Affinity Capture-MS Homo sapiens
107 RSL24D1  
Affinity Capture-MS Homo sapiens
108 TARDBP 23435
Affinity Capture-MS Homo sapiens
109 BTF3 689
Affinity Capture-MS Homo sapiens
110 PRPF38A 84950
Affinity Capture-MS Homo sapiens
111 THRAP3 9967
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
112 HNRNPD 3184
Affinity Capture-MS Homo sapiens
113 CAND1 55832
Affinity Capture-MS Homo sapiens
114 RSBN1  
Affinity Capture-MS Homo sapiens
115 MPHOSPH10 10199
Affinity Capture-MS Homo sapiens
116 RPS3 6188
Affinity Capture-MS Homo sapiens
117 RNPS1 10921
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
118 B3GNT2 10678
Affinity Capture-MS Homo sapiens
119 CDK11B 984
Affinity Capture-MS Homo sapiens
120 PRPF38B 55119
Affinity Capture-MS Homo sapiens
121 RRP12 23223
Affinity Capture-MS Homo sapiens
122 PRC1 9055
Affinity Capture-MS Homo sapiens
123 SRRM2 23524
Affinity Capture-MS Homo sapiens
124 OBSL1 23363
Affinity Capture-MS Homo sapiens
125 PAK1IP1  
Affinity Capture-MS Homo sapiens
126 MRPS7 51081
Affinity Capture-MS Homo sapiens
127 POP1 10940
Affinity Capture-MS Homo sapiens
128 CUL1 8454
Affinity Capture-MS Homo sapiens
129 FASTKD2  
Affinity Capture-MS Homo sapiens
130 RRP7A 27341
Affinity Capture-MS Homo sapiens
131 DHX36 170506
Affinity Capture-MS Homo sapiens
132 GAR1 54433
Affinity Capture-MS Homo sapiens
133 ZCRB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
134 XPO1 7514
Affinity Capture-MS Homo sapiens
135 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
136 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
137 RPL4 6124
Affinity Capture-MS Homo sapiens
138 RBM28 55131
Affinity Capture-MS Homo sapiens
139 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
140 PSMD14 10213
Affinity Capture-MS Homo sapiens
141 ACIN1 22985
Affinity Capture-MS Homo sapiens
142 ZBTB48  
Affinity Capture-MS Homo sapiens
143 VRK1 7443
Affinity Capture-MS Homo sapiens
144 DDX10  
Affinity Capture-MS Homo sapiens
145 NKRF 55922
Affinity Capture-MS Homo sapiens
146 REXO4  
Affinity Capture-MS Homo sapiens
147 LUC7L2 51631
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
148 SCAF11  
Affinity Capture-MS Homo sapiens
149 MAGOH 4116
Affinity Capture-MS Homo sapiens
150 RPLP0 6175
Affinity Capture-MS Homo sapiens
151 DDX27 55661
Affinity Capture-MS Homo sapiens
152 CYLD  
Affinity Capture-MS Homo sapiens
153 ASB18  
Affinity Capture-MS Homo sapiens
154 C7orf50 84310
Affinity Capture-MS Homo sapiens
155 RSL1D1 26156
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
156 PPAN-P2RY11  
Affinity Capture-MS Homo sapiens
157 RPL32 6161
Affinity Capture-MS Homo sapiens
158 ATL3 25923
Co-fractionation Homo sapiens
159 RPS2 6187
Affinity Capture-MS Homo sapiens
160 MRPS35 60488
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
161 RC3H2  
Affinity Capture-MS Homo sapiens
162 ZBTB24  
Affinity Capture-MS Homo sapiens
163 WDR33 55339
Affinity Capture-MS Homo sapiens
164 SETD2  
Affinity Capture-MS Homo sapiens
165 SRSF5 6430
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 EGFR 1956
Negative Genetic Homo sapiens
167 MYC  
Affinity Capture-MS Homo sapiens
168 CEBPZ  
Affinity Capture-MS Homo sapiens
169 NOL12 79159
Affinity Capture-MS Homo sapiens
170 GZF1  
Affinity Capture-MS Homo sapiens
171 DDB1 1642
Affinity Capture-MS Homo sapiens
172 SNW1 22938
Affinity Capture-MS Homo sapiens
173 DDRGK1 65992
Affinity Capture-MS Homo sapiens
174 FYTTD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
175 NOP16 51491
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
177 RPL26 6154
Affinity Capture-MS Homo sapiens
178 FTSJ3 117246
Affinity Capture-MS Homo sapiens
179 FAM120A 23196
Affinity Capture-MS Homo sapiens
180 RPL13 6137
Affinity Capture-MS Homo sapiens
181 SURF6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 TERF2  
Two-hybrid Homo sapiens
183 TOE1 114034
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
184 TP53 7157
Affinity Capture-MS Homo sapiens
185 FOLR1 2348
Affinity Capture-MS Homo sapiens
186 FXR1 8087
Affinity Capture-MS Homo sapiens
187 SF3B4 10262
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
188 KNOP1 400506
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
189 RPS4X 6191
Affinity Capture-MS Homo sapiens
190 C1orf35  
Affinity Capture-MS Homo sapiens
191 LUC7L 55692
Affinity Capture-MS Homo sapiens
192 RPS5 6193
Affinity Capture-MS Homo sapiens
193 NIFK 84365
Affinity Capture-MS Homo sapiens
194 MRPS21  
Affinity Capture-MS Homo sapiens
195 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 RBM23  
Affinity Capture-MS Homo sapiens
197 DDX56  
Affinity Capture-MS Homo sapiens
198 NOC2L 26155
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
199 YBX3 8531
Affinity Capture-MS Homo sapiens
200 RPL7A 6130
Affinity Capture-MS Homo sapiens
201 GLYR1 84656
Affinity Capture-MS Homo sapiens
202 TOPORS  
Affinity Capture-MS Homo sapiens
203 KRAS 3845
Negative Genetic Homo sapiens
204 HERC5 51191
Affinity Capture-MS Homo sapiens
205 CPSF6 11052
Affinity Capture-MS Homo sapiens
206 PRKRIR  
Affinity Capture-MS Homo sapiens
207 RANBP2 5903
Affinity Capture-MS Homo sapiens
208 RALY 22913
Affinity Capture-MS Homo sapiens
209 ZNF668  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
210 RPL26L1 51121
Affinity Capture-MS Homo sapiens
211 ZSCAN25  
Affinity Capture-MS Homo sapiens
212 DNAJC8 22826
Affinity Capture-MS Homo sapiens
213 YWHAE 7531
Affinity Capture-MS Homo sapiens
214 CENPC  
Affinity Capture-MS Homo sapiens
215 EPB41L5 57669
Affinity Capture-MS Homo sapiens
216 LARP1B 55132
Affinity Capture-MS Homo sapiens
217 RPS19 6223
Affinity Capture-MS Homo sapiens
218 SSB 6741
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
219 SRSF8 10929
Affinity Capture-MS Homo sapiens
220 Rrp1b 72462
Affinity Capture-MS Mus musculus
221 TRUB2  
Affinity Capture-MS Homo sapiens
222 RPL10A 4736
Affinity Capture-MS Homo sapiens
223 LLPH  
Affinity Capture-MS Homo sapiens
224 WDR74 54663
Affinity Capture-MS Homo sapiens
225 ZNF638 27332
Affinity Capture-MS Homo sapiens
226 CCDC137  
Affinity Capture-MS Homo sapiens
227 IMP3 55272
Affinity Capture-MS Homo sapiens
228 ZNF358 140467
Affinity Capture-MS Homo sapiens
229 CDK12 51755
Affinity Capture-MS Homo sapiens
230 IQGAP1 8826
Affinity Capture-MS Homo sapiens
231 TRIM56 81844
Affinity Capture-MS Homo sapiens
232 SF3A2 8175
Affinity Capture-MS Homo sapiens
233 C17orf85  
Affinity Capture-MS Homo sapiens
234 RC3H1 149041
Affinity Capture-MS Homo sapiens
235 RPL29 6159
Affinity Capture-MS Homo sapiens
236 DDX18 8886
Affinity Capture-MS Homo sapiens
237 NHP2 55651
Affinity Capture-MS Homo sapiens
238 FAM111A 63901
Affinity Capture-MS Homo sapiens
239 CSNK2B 1460
Affinity Capture-MS Homo sapiens
240 MTERF3  
Affinity Capture-MS Homo sapiens
241 RBM19 9904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
242 BRIX1 55299
Affinity Capture-MS Homo sapiens
243 CLK2 1196
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
244 DDX31  
Affinity Capture-MS Homo sapiens
245 CLK4  
Affinity Capture-MS Homo sapiens
246 SCAF1  
Affinity Capture-MS Homo sapiens
247 PARK2  
Affinity Capture-MS Homo sapiens
248 RPS10 6204
Affinity Capture-MS Homo sapiens
249 XRN1 54464
Affinity Capture-MS Homo sapiens
250 NOP2 4839
Affinity Capture-MS Homo sapiens
251 RPL5 6125
Affinity Capture-MS Homo sapiens
252 ZCCHC17  
Affinity Capture-MS Homo sapiens
253 BARD1 580
Affinity Capture-MS Homo sapiens
254 NTRK1 4914
Affinity Capture-MS Homo sapiens
255 U2AF2 11338
Affinity Capture-MS Homo sapiens
256 RPLP1 6176
Affinity Capture-MS Homo sapiens
257 DHX9 1660
Affinity Capture-MS Homo sapiens
258 ZC3H14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
259 NKTR  
Affinity Capture-MS Homo sapiens
260 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
261 NOP14 8602
Affinity Capture-MS Homo sapiens
262 RBM10  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
263 RPL11 6135
Affinity Capture-MS Homo sapiens
264 LARP1 23367
Affinity Capture-MS Homo sapiens
265 WDR46  
Affinity Capture-MS Homo sapiens
266 RBBP6 5930
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
267 KMT2A  
Affinity Capture-MS Homo sapiens
268 METTL14  
Affinity Capture-MS Homo sapiens
269 CHERP 10523
Affinity Capture-MS Homo sapiens
270 ECT2 1894
Affinity Capture-MS Homo sapiens
271 ZFR 51663
Affinity Capture-MS Homo sapiens
272 ZC3H8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
273 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
274 DHX30 22907
Affinity Capture-MS Homo sapiens
275 PDCD11 22984
Affinity Capture-MS Homo sapiens
276 BUD13  
Affinity Capture-MS Homo sapiens
277 ZNF777  
Affinity Capture-MS Homo sapiens
278 PRR3  
Affinity Capture-MS Homo sapiens
279 RPS13 6207
Affinity Capture-MS Homo sapiens
280 ZC3H18  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
281 YWHAQ 10971
Affinity Capture-MS Homo sapiens
282 RPS14 6208
Affinity Capture-MS Homo sapiens
283 CLASRP  
Affinity Capture-MS Homo sapiens
284 RPL12 6136
Affinity Capture-MS Homo sapiens
285 HP1BP3 50809
Affinity Capture-MS Homo sapiens
286 ZNF121  
Affinity Capture-MS Homo sapiens
287 GPATCH8  
Affinity Capture-MS Homo sapiens
288 RPL18 6141
Affinity Capture-MS Homo sapiens
289 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
290 PROSC 11212
Affinity Capture-MS Homo sapiens
291 ZNF574  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
292 PIP5K1A 8394
Affinity Capture-MS Homo sapiens
293 DDX50 79009
Affinity Capture-MS Homo sapiens
294 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
295 CLK1  
Affinity Capture-MS Homo sapiens
296 EPB41L4B 54566
Affinity Capture-MS Homo sapiens
297 PRDM15  
Affinity Capture-MS Homo sapiens
298 CDC40  
Affinity Capture-MS Homo sapiens
299 KIAA1429 25962
Affinity Capture-MS Homo sapiens
300 URB1 9875
Affinity Capture-MS Homo sapiens
301 MKI67  
Affinity Capture-MS Homo sapiens
302 RNPC3  
Affinity Capture-MS Homo sapiens
303 NF1 4763
Negative Genetic Homo sapiens
304 SNIP1  
Affinity Capture-MS Homo sapiens
305 CDK13 8621
Affinity Capture-MS Homo sapiens
306 GLUL 2752
Affinity Capture-MS Homo sapiens
307 AKAP17A  
Affinity Capture-MS Homo sapiens
308 RPL8 6132
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
309 TAF1C  
Affinity Capture-MS Homo sapiens
310 SLBP  
Affinity Capture-MS Homo sapiens
311 ZC3H13 23091
Affinity Capture-MS Homo sapiens
312 RBM34  
Affinity Capture-MS Homo sapiens
313 Safb  
Two-hybrid Rattus norvegicus
314 SSRP1 6749
Affinity Capture-MS Homo sapiens
315 PPARGC1A  
Affinity Capture-Western Homo sapiens
316 SRSF7 6432
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
317 COMMD1 150684
Affinity Capture-MS Homo sapiens
318 CDKN2A 1029
Affinity Capture-MS Homo sapiens
319 CASC3  
Affinity Capture-MS Homo sapiens
320 GNL2 29889
Affinity Capture-MS Homo sapiens
321 UBE2H 7328
Affinity Capture-MS Homo sapiens
322 RIT1 6016
Negative Genetic Homo sapiens
323 UTP18  
Affinity Capture-MS Homo sapiens
324 RSBN1L  
Affinity Capture-MS Homo sapiens
325 DDX24 57062
Affinity Capture-MS Homo sapiens
326 RPS3A 6189
Affinity Capture-MS Homo sapiens
327 BCLAF1 9774
Affinity Capture-MS Homo sapiens
328 PPIE 10450
Affinity Capture-MS Homo sapiens
329 RPL13A 23521
Affinity Capture-MS Homo sapiens
330 RPL37A 6168
Affinity Capture-MS Homo sapiens
331 SUB1 10923
Co-fractionation Homo sapiens
332 DHX8 1659
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
333 NGRN  
Affinity Capture-MS Homo sapiens
334 UTP23  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
335 DHX57 90957
Affinity Capture-MS Homo sapiens
336 MRPL52  
Affinity Capture-MS Homo sapiens
337 AQR 9716
Affinity Capture-MS Homo sapiens
338 APP 351
Reconstituted Complex Homo sapiens
339 WDR36 134430
Affinity Capture-MS Homo sapiens
340 COPS5 10987
Affinity Capture-MS Homo sapiens
341 PABPC4L 132430
Affinity Capture-MS Homo sapiens
342 ISY1 57461
Affinity Capture-MS Homo sapiens
343 MRPS5 64969
Affinity Capture-MS Homo sapiens
344 RPL24 6152
Co-fractionation Homo sapiens
345 NCOA5  
Affinity Capture-MS Homo sapiens
346 MRPS24 64951
Affinity Capture-MS Homo sapiens
347 ZCCHC3  
Affinity Capture-MS Homo sapiens
348 STAU2 27067
Affinity Capture-MS Homo sapiens
349 PRKRA 8575
Affinity Capture-MS Homo sapiens
350 DDX51  
Affinity Capture-MS Homo sapiens
351 EED  
Affinity Capture-MS Homo sapiens
352 NOC3L 64318
Affinity Capture-MS Homo sapiens
353 RRP8  
Affinity Capture-MS Homo sapiens
354 MYCN  
Affinity Capture-MS Homo sapiens
355 MAK16  
Affinity Capture-MS Homo sapiens
356 COMMD4 54939
Affinity Capture-MS Homo sapiens
357 KRI1  
Affinity Capture-MS Homo sapiens
358 CTCF  
Affinity Capture-MS Homo sapiens
359 CCDC86  
Affinity Capture-MS Homo sapiens
360 E2F4  
Affinity Capture-MS Homo sapiens
361 ZKSCAN8  
Affinity Capture-MS Homo sapiens
362 MRPS34 65993
Affinity Capture-MS Homo sapiens
363 STAU1 6780
Affinity Capture-MS Homo sapiens
364 TTF1  
Affinity Capture-MS Homo sapiens
365 ZNF22  
Affinity Capture-MS Homo sapiens
366 PTCD3 55037
Affinity Capture-MS Homo sapiens
367 CD2BP2 10421
Affinity Capture-MS Homo sapiens
368 IFI16 3428
Affinity Capture-MS Homo sapiens
369 DDX54 79039
Affinity Capture-MS Homo sapiens
370 SMC1A 8243
Affinity Capture-MS Homo sapiens
371 ZFC3H1 196441
Affinity Capture-MS Homo sapiens
372 SPTY2D1  
Affinity Capture-MS Homo sapiens
373 MRPS33  
Affinity Capture-MS Homo sapiens
374 GLTSCR2  
Affinity Capture-MS Homo sapiens
375 RPF1  
Affinity Capture-MS Homo sapiens
376 ELAVL2 1993
Affinity Capture-MS Homo sapiens
377 SRSF11 9295
Affinity Capture-MS Homo sapiens
378 RBM5  
Affinity Capture-MS Homo sapiens
379 BMS1  
Affinity Capture-MS Homo sapiens
380 PRPF4B 8899
Affinity Capture-MS Homo sapiens
381 RPLP2 6181
Affinity Capture-MS Homo sapiens
382 TRIM31  
Affinity Capture-MS Homo sapiens
383 CLK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
384 PNN 5411
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
385 NELFCD 51497
Affinity Capture-MS Homo sapiens
386 RPL35 11224
Affinity Capture-MS Homo sapiens
387 NAT10 55226
Affinity Capture-MS Homo sapiens
388 SRSF1 6426
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
389 COMMD2 51122
Affinity Capture-MS Homo sapiens
390 XAB2 56949
Affinity Capture-MS Homo sapiens
391 RPL3 6122
Affinity Capture-MS Homo sapiens
392 BBX 56987
Affinity Capture-MS Homo sapiens
393 RPL7 6129
Affinity Capture-MS Homo sapiens
394 SUZ12  
Affinity Capture-MS Homo sapiens
395 DKC1 1736
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
396 OASL 8638
Affinity Capture-MS Homo sapiens
397 COMMD6 170622
Affinity Capture-MS Homo sapiens
398 SRSF10 10772
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
399 CACTIN  
Affinity Capture-MS Homo sapiens
400 NOL6 65083
Affinity Capture-MS Homo sapiens
401 C10orf2 56652
Affinity Capture-MS Homo sapiens
402 H2AFX 3014
Affinity Capture-MS Homo sapiens
403 YTHDC2 64848
Affinity Capture-MS Homo sapiens
404 DIS3L2 129563
Affinity Capture-MS Homo sapiens
405 ZNF689  
Affinity Capture-MS Homo sapiens
406 SRRM1 10250
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
407 MINA 84864
Affinity Capture-MS Homo sapiens
408 NOL10  
Affinity Capture-MS Homo sapiens
409 PPIG 9360
Affinity Capture-MS Homo sapiens
410 PHRF1  
Affinity Capture-MS Homo sapiens
411 PPHLN1  
Affinity Capture-MS Homo sapiens
412 SAP18 10284
Affinity Capture-MS Homo sapiens
413 BOP1 23246
Affinity Capture-MS Homo sapiens
414 DGCR8  
Affinity Capture-MS Homo sapiens
415 RPS15 6209
Affinity Capture-MS Homo sapiens
416 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
417 NSA2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
418 EIF4A3 9775
Affinity Capture-MS Homo sapiens
419 TERF1 7013
Two-hybrid Homo sapiens
420 DHX16 8449
Affinity Capture-MS Homo sapiens
421 MOV10 4343
Affinity Capture-MS Homo sapiens
422 MRPS9 64965
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
423 UPF1 5976
Affinity Capture-MS Homo sapiens
424 RPS6 6194
Affinity Capture-MS Homo sapiens
425 ZNF629 23361
Affinity Capture-MS Homo sapiens
426 C9orf72  
Affinity Capture-MS Homo sapiens
427 AAMP 14
Affinity Capture-MS Homo sapiens
428 MRPL32 64983
Affinity Capture-MS Homo sapiens
429 RPL17 6139
Affinity Capture-MS Homo sapiens
430 CDC5L 988
Affinity Capture-MS Homo sapiens
431 SRRT 51593
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here