Gene description for PNN
Gene name pinin, desmosome associated protein
Gene symbol PNN
Other names/aliases DRS
DRSP
SDK3
memA
Species Homo sapiens
 Database cross references - PNN
ExoCarta ExoCarta_5411
Vesiclepedia VP_5411
Entrez Gene 5411
HGNC 9162
MIM 603154
UniProt Q9H307  
 PNN identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
 Gene ontology annotations for PNN
Molecular Function
    DNA binding GO:0003677 IEA
    RNA binding GO:0003723 HDA
    structural molecule activity GO:0005198 NAS
    protein binding GO:0005515 IPI
Biological Process
    mRNA splicing, via spliceosome GO:0000398 IC
    cell adhesion GO:0007155 TAS
Subcellular Localization
    nucleoplasm GO:0005654 TAS
    intermediate filament GO:0005882 TAS
    plasma membrane GO:0005886 TAS
    cell-cell junction GO:0005911 TAS
    membrane GO:0016020 HDA
    nuclear speck GO:0016607 IDA
    desmosome GO:0030057 IEA
    exon-exon junction complex GO:0035145 IDA
    catalytic step 2 spliceosome GO:0071013 IBA
    catalytic step 2 spliceosome GO:0071013 IDA
 Experiment description of studies that identified PNN in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
6
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
11
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PNN
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CFAP20 29105
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 UBE2H 7328
Affinity Capture-MS Homo sapiens
3 CAMKV 79012
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
5 CPSF6 11052
Affinity Capture-MS Homo sapiens
6 RALYL 138046
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 LUZP4  
Affinity Capture-MS Homo sapiens
8 BIRC6 57448
Cross-Linking-MS (XL-MS) Homo sapiens
9 RSBN1L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 BRDT  
Affinity Capture-MS Homo sapiens
11 CALM3 808
Affinity Capture-MS Homo sapiens
12 RBM22 55696
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 ANLN 54443
Affinity Capture-MS Homo sapiens
14 WWP1 11059
Affinity Capture-MS Homo sapiens
15 COX15 1355
Affinity Capture-MS Homo sapiens
16 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
17 SRPK2 6733
Affinity Capture-MS Homo sapiens
18 FMR1 2332
Affinity Capture-MS Homo sapiens
19 ZC3H14  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
20 EPB41L5 57669
Affinity Capture-MS Homo sapiens
21 SF3B1 23451
Affinity Capture-MS Homo sapiens
22 HIST1H2BH 8345
Cross-Linking-MS (XL-MS) Homo sapiens
23 DHX8 1659
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 KIF20A 10112
Affinity Capture-MS Homo sapiens
25 HNRNPC 3183
Affinity Capture-MS Homo sapiens
26 CSNK2A1 1457
Biochemical Activity Homo sapiens
27 PPIA 5478
Cross-Linking-MS (XL-MS) Homo sapiens
28 CAND1 55832
Cross-Linking-MS (XL-MS) Homo sapiens
29 RSBN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 AQR 9716
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 PRPF40A 55660
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 PARK7 11315
Affinity Capture-MS Homo sapiens
33 SNRPF 6636
Affinity Capture-MS Homo sapiens
34 SNRPD2 6633
Affinity Capture-MS Homo sapiens
35 ILF2 3608
Affinity Capture-MS Homo sapiens
36 GSK3A 2931
Affinity Capture-MS Homo sapiens
37 LARP4B 23185
Affinity Capture-MS Homo sapiens
38 CUL7 9820
Affinity Capture-MS Homo sapiens
39 DDX23 9416
Proximity Label-MS Homo sapiens
40 GSPT2 23708
Affinity Capture-MS Homo sapiens
41 RNPS1 10921
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
42 B3GNT2 10678
Affinity Capture-MS Homo sapiens
43 SNRPB 6628
Affinity Capture-MS Homo sapiens
44 DENND2D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 KIF23 9493
Affinity Capture-MS Homo sapiens
46 Sap18  
Co-purification Mus musculus
47 PNISR  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
48 NFKBIL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 PUF60 22827
Affinity Capture-MS Homo sapiens
50 SRSF10 10772
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 TRDN 10345
Cross-Linking-MS (XL-MS) Homo sapiens
52 PRC1 9055
Affinity Capture-MS Homo sapiens
53 VANGL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 SRRM2 23524
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
55 SNRPC 6631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 ZMYND11 10771
Affinity Capture-MS Homo sapiens
57 OBSL1 23363
Affinity Capture-MS Homo sapiens
58 SF3A2 8175
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 SMOC1 64093
Affinity Capture-MS Homo sapiens
61 SARNP 84324
Affinity Capture-MS Homo sapiens
62 UCHL5 51377
Cross-Linking-MS (XL-MS) Homo sapiens
63 ABT1 29777
Affinity Capture-MS Homo sapiens
64 NDUFAF1  
Affinity Capture-MS Homo sapiens
65 KLHL20  
Affinity Capture-MS Homo sapiens
66 DDX41 51428
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 MECP2 4204
Affinity Capture-MS Homo sapiens
68 MYCN  
Affinity Capture-MS Homo sapiens
69 RBM42  
Affinity Capture-MS Homo sapiens
70 MAD2L1 4085
Affinity Capture-MS Homo sapiens
71 SREK1 140890
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 PABPC4 8761
Cross-Linking-MS (XL-MS) Homo sapiens
73 PSMC3 5702
Affinity Capture-MS Homo sapiens
74 RBM14 10432
Affinity Capture-MS Homo sapiens
75 USP37  
Proximity Label-MS Homo sapiens
76 KIF14 9928
Affinity Capture-MS Homo sapiens
77 CCDC9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 PES1 23481
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
79 KIDINS220 57498
Cross-Linking-MS (XL-MS) Homo sapiens
80 EPB41L3 23136
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 KRT8 3856
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
82 NUMA1 4926
Affinity Capture-MS Homo sapiens
83 CLK2 1196
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
84 DLD 1738
Affinity Capture-MS Homo sapiens
85 POLD1 5424
Affinity Capture-MS Homo sapiens
86 SCAF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 CHMP4C 92421
Affinity Capture-MS Homo sapiens
88 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
89 DDX21 9188
Affinity Capture-MS Homo sapiens
90 PARK2  
Affinity Capture-MS Homo sapiens
91 RBM6 10180
Affinity Capture-MS Homo sapiens
92 CTBP1 1487
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
93 SUPT5H 6829
Affinity Capture-MS Homo sapiens
94 SNRPA 6626
Affinity Capture-MS Homo sapiens
95 TCEA2  
Affinity Capture-MS Homo sapiens
96 ACIN1 22985
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
97 SRSF6 6431
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
98 CRNKL1 51340
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 Spred2  
Affinity Capture-MS Mus musculus
100 CD2BP2 10421
Affinity Capture-MS Homo sapiens
101 ZCCHC17  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
102 CHMP4B 128866
Affinity Capture-MS Homo sapiens
103 FAM9A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 BARD1 580
Affinity Capture-MS Homo sapiens
105 NTRK1 4914
Affinity Capture-MS Homo sapiens
106 HIVEP3 59269
Cross-Linking-MS (XL-MS) Homo sapiens
107 U2AF2 11338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 RBMX2  
Affinity Capture-MS Homo sapiens
109 LUC7L2 51631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 FAM133A 286499
Affinity Capture-MS Homo sapiens
111 ARRDC3 57561
Affinity Capture-MS Homo sapiens
112 RBM33  
Affinity Capture-MS Homo sapiens
113 HECTD1 25831
Affinity Capture-MS Homo sapiens
114 MAGOH 4116
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
115 HIST1H2BK 85236
Cross-Linking-MS (XL-MS) Homo sapiens
116 BRD4 23476
Affinity Capture-MS Homo sapiens
117 DDX39B 7919
Affinity Capture-MS Homo sapiens
118 NCL 4691
Cross-Linking-MS (XL-MS) Homo sapiens
119 DNM1L 10059
Affinity Capture-MS Homo sapiens
120 SRPK1 6732
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
121 SNRPB2 6629
Affinity Capture-MS Homo sapiens
122 YWHAH 7533
Affinity Capture-MS Homo sapiens
123 ELAVL2 1993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 MKI67  
Affinity Capture-MS Homo sapiens
125 BCLAF1 9774
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
126 SRSF11 9295
Affinity Capture-MS Homo sapiens
127 RBBP6 5930
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 EPB41L1 2036
Affinity Capture-MS Homo sapiens
129 PABPC5 140886
Affinity Capture-MS Homo sapiens
130 ZBTB2 57621
Affinity Capture-MS Homo sapiens
131 RBM39 9584
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
132 PRPF4B 8899
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 FANCD2  
Affinity Capture-MS Homo sapiens
134 C11orf57  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
135 CLK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 GPALPP1  
Affinity Capture-MS Homo sapiens
137 SIRT7  
Affinity Capture-MS Homo sapiens
138 SRSF4 6429
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
139 RNF43  
Proximity Label-MS Homo sapiens
140 BRD2  
Affinity Capture-MS Homo sapiens
141 XAB2 56949
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
143 FUS 2521
Affinity Capture-MS Homo sapiens
144 Wash  
Affinity Capture-MS Mus musculus
145 ZC3H11A  
Affinity Capture-MS Homo sapiens
146 KRT27 342574
Two-hybrid Homo sapiens
147 SF3A1 10291
Affinity Capture-MS Homo sapiens
148 YTHDC1  
Affinity Capture-MS Homo sapiens
149 CDK2 1017
Affinity Capture-MS Homo sapiens
150 KCNE3  
Affinity Capture-MS Homo sapiens
151 PIP4K2A 5305
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
152 PRPF19 27339
Affinity Capture-MS Homo sapiens
153 MYC  
Affinity Capture-MS Homo sapiens
154 RPA3 6119
Proximity Label-MS Homo sapiens
155 ZC3H18  
Co-fractionation Homo sapiens
156 C1QTNF1 114897
Affinity Capture-MS Homo sapiens
157 DLST 1743
Affinity Capture-MS Homo sapiens
158 RNF151  
Affinity Capture-MS Homo sapiens
159 TOP1 7150
Affinity Capture-MS Homo sapiens
160 WSB2 55884
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
161 RHOB 388
Proximity Label-MS Homo sapiens
162 FYTTD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
163 ARGLU1  
Affinity Capture-MS Homo sapiens
164 NOG 9241
Affinity Capture-MS Homo sapiens
165 AARS 16
Cross-Linking-MS (XL-MS) Homo sapiens
166 KRT19 3880
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
167 HIST1H2BC 8347
Cross-Linking-MS (XL-MS) Homo sapiens
168 BRD3 8019
Affinity Capture-MS Homo sapiens
169 Ccdc9  
Affinity Capture-MS Mus musculus
170 NKAP 79576
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
171 PAIP1 10605
Affinity Capture-MS Homo sapiens
172 NOS1AP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
173 KRT18 3875
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
174 GRK5 2869
Affinity Capture-MS Homo sapiens
175 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
176 C17orf85  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 BCAS2 10286
Affinity Capture-MS Homo sapiens
178 PARP1 142
Affinity Capture-MS Homo sapiens
179 SRRM1 10250
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
180 RPL6 6128
Co-fractionation Homo sapiens
181 PPIE 10450
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 MDK 4192
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
183 ERH 2079
Affinity Capture-MS Homo sapiens
184 SSRP1 6749
Affinity Capture-MS Homo sapiens
185 PPIG 9360
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 ISY1 57461
Affinity Capture-MS Homo sapiens
187 Rbm8a  
Affinity Capture-MS Mus musculus
188 SAP18 10284
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
189 PDHA1 5160
Affinity Capture-MS Homo sapiens
190 NKTR  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
191 THRAP3 9967
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
192 C1orf35  
Affinity Capture-MS Homo sapiens
193 PRMT1 3276
Affinity Capture-MS Homo sapiens
194 CDC40  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 CHD4 1108
Affinity Capture-MS Homo sapiens
196 EIF4A3 9775
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
197 EPB41L2 2037
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 DDX58 23586
Affinity Capture-RNA Homo sapiens
199 PTGER3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
200 SFSWAP  
Affinity Capture-MS Homo sapiens
201 EDA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 SNIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
203 SRSF3 6428
Affinity Capture-MS Homo sapiens
204 API5 8539
Affinity Capture-MS Homo sapiens
205 SRSF7 6432
Affinity Capture-MS Homo sapiens
206 PINK1  
Affinity Capture-MS Homo sapiens
207 AKAP17A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 RBM8A 9939
Affinity Capture-MS Homo sapiens
209 DAXX  
Affinity Capture-MS Homo sapiens
210 TOPORS  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
211 SNW1 22938
Affinity Capture-MS Homo sapiens
212 KRAS 3845
Affinity Capture-MS Homo sapiens
Synthetic Lethality Homo sapiens
213 CASC3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
214 AR 367
Proximity Label-MS Homo sapiens
215 ARHGAP24  
Affinity Capture-MS Homo sapiens
216 RBM12B  
Two-hybrid Homo sapiens
217 VANGL1 81839
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 SNRPA1 6627
Affinity Capture-MS Homo sapiens
219 SP7  
Proximity Label-MS Homo sapiens
220 LUC7L 55692
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
221 Rnps1  
Two-hybrid Mus musculus
222 CDC5L 988
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here