Gene description for SRPK2
Gene name SRSF protein kinase 2
Gene symbol SRPK2
Other names/aliases SFRSK2
Species Homo sapiens
 Database cross references - SRPK2
ExoCarta ExoCarta_6733
Vesiclepedia VP_6733
Entrez Gene 6733
HGNC 11306
MIM 602980
UniProt P78362  
 SRPK2 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
 Gene ontology annotations for SRPK2
Molecular Function
    magnesium ion binding GO:0000287 IDA
    RNA binding GO:0003723 HDA
    protein serine/threonine kinase activity GO:0004674 IBA
    protein serine/threonine kinase activity GO:0004674 IDA
    protein serine/threonine kinase activity GO:0004674 IGI
    3-phosphoinositide-dependent protein kinase activity GO:0004676 IEA
    DNA-dependent protein kinase activity GO:0004677 IEA
    AMP-activated protein kinase activity GO:0004679 IEA
    eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 IEA
    ribosomal protein S6 kinase activity GO:0004711 IEA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IDA
    histone H3S10 kinase activity GO:0035175 IEA
    histone H3T11 kinase activity GO:0035402 IEA
    histone H3T6 kinase activity GO:0035403 IEA
    histone H2AXS139 kinase activity GO:0035979 IEA
    histone H3S28 kinase activity GO:0044022 IEA
    histone H4S1 kinase activity GO:0044023 IEA
    histone H2AS1 kinase activity GO:0044024 IEA
    histone H2BS14 kinase activity GO:0044025 IEA
    14-3-3 protein binding GO:0071889 ISS
    histone H3T3 kinase activity GO:0072354 IEA
    histone H2AS121 kinase activity GO:0072371 IEA
    Rho-dependent protein serine/threonine kinase activity GO:0072518 IEA
    protein serine kinase activity GO:0106310 IEA
    histone H2BS36 kinase activity GO:0140823 IEA
    histone H3S57 kinase activity GO:0140855 IEA
    histone H3T45 kinase activity GO:0140857 IEA
    histone H2AT120 kinase activity GO:1990244 IEA
Biological Process
    spliceosomal complex assembly GO:0000245 IBA
    spliceosomal complex assembly GO:0000245 IDA
    angiogenesis GO:0001525 ISS
    protein phosphorylation GO:0006468 IDA
    positive regulation of cell population proliferation GO:0008284 IDA
    RNA splicing GO:0008380 IDA
    positive regulation of gene expression GO:0010628 ISS
    peptidyl-serine phosphorylation GO:0018105 IGI
    cell differentiation GO:0030154 IEA
    nuclear speck organization GO:0035063 ISS
    intracellular signal transduction GO:0035556 IBA
    intracellular signal transduction GO:0035556 IDA
    positive regulation of neuron apoptotic process GO:0043525 ISS
    positive regulation of viral genome replication GO:0045070 IDA
    negative regulation of viral genome replication GO:0045071 IDA
    innate immune response GO:0045087 IC
    positive regulation of cell cycle GO:0045787 ISS
    regulation of mRNA splicing, via spliceosome GO:0048024 TAS
    regulation of mRNA processing GO:0050684 IBA
    R-loop processing GO:0062176 IDA
Subcellular Localization
    chromatin GO:0000785 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    nuclear speck GO:0016607 IDA
    presynapse GO:0098793 IEA
 Experiment description of studies that identified SRPK2 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SRPK2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SLC39A12  
Affinity Capture-MS Homo sapiens
2 RPSAP58 388524
Affinity Capture-MS Homo sapiens
3 SRPK2 6733
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
4 AES 166
Two-hybrid Homo sapiens
5 SCAF4 57466
Affinity Capture-MS Homo sapiens
6 LRRN4CL 221091
Biochemical Activity Homo sapiens
7 SOX2  
Affinity Capture-MS Homo sapiens
8 APEX1 328
Biochemical Activity Homo sapiens
9 NOL8  
Affinity Capture-MS Homo sapiens
10 SNRNP70 6625
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
11 PELI1 57162
Biochemical Activity Homo sapiens
12 MPP3  
Biochemical Activity Homo sapiens
13 C18orf25 147339
Biochemical Activity Homo sapiens
14 RSRP1  
Biochemical Activity Homo sapiens
15 CPSF7 79869
Two-hybrid Homo sapiens
16 KCNN2  
Biochemical Activity Homo sapiens
17 Btf3  
Two-hybrid Mus musculus
18 FBL 2091
Proximity Label-MS Homo sapiens
19 TFIP11  
Affinity Capture-MS Homo sapiens
20 RPF2 84154
Affinity Capture-MS Homo sapiens
21 RPL39L  
Biochemical Activity Homo sapiens
22 FOXQ1  
Affinity Capture-MS Homo sapiens
23 WDR5 11091
Biochemical Activity Homo sapiens
24 SREK1 140890
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
25 AURKA 6790
Biochemical Activity Homo sapiens
26 TOLLIP 54472
Proximity Label-MS Homo sapiens
27 TCOF1 6949
Biochemical Activity Homo sapiens
28 RNF4 6047
Biochemical Activity Homo sapiens
29 MARCH10  
Biochemical Activity Homo sapiens
30 IFIT5 24138
Biochemical Activity Homo sapiens
31 RRP9 9136
Affinity Capture-MS Homo sapiens
32 SRSF3 6428
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
33 PURG  
Affinity Capture-MS Homo sapiens
34 RPL18A 6142
Affinity Capture-MS Homo sapiens
35 PABPC1 26986
Affinity Capture-MS Homo sapiens
36 FOXL2  
Affinity Capture-MS Homo sapiens
37 DRAP1 10589
Biochemical Activity Homo sapiens
38 GABARAP 11337
Biochemical Activity Homo sapiens
39 TTN 7273
Biochemical Activity Homo sapiens
40 RPL31 6160
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 CBX5 23468
Co-fractionation Homo sapiens
Biochemical Activity Homo sapiens
42 ALKBH3  
Biochemical Activity Homo sapiens
43 CBX6  
Affinity Capture-MS Homo sapiens
44 TNFRSF10C  
Biochemical Activity Homo sapiens
45 EIF1AY 9086
Biochemical Activity Homo sapiens
46 ZRSR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
47 RRP1B 23076
Affinity Capture-MS Homo sapiens
48 CLDN19  
Biochemical Activity Homo sapiens
49 DDX39B 7919
Affinity Capture-MS Homo sapiens
50 GTPBP4 23560
Affinity Capture-MS Homo sapiens
51 SRPK1 6732
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
52 CCDC28A  
Biochemical Activity Homo sapiens
53 BCLAF1 9774
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 EPB41L1 2036
Biochemical Activity Homo sapiens
55 RBM39 9584
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
56 HBS1L 10767
Biochemical Activity Homo sapiens
57 AHCYL1 10768
Biochemical Activity Homo sapiens
58 DDX50 79009
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
59 MAGEB1  
Biochemical Activity Homo sapiens
60 ZSCAN12  
Two-hybrid Homo sapiens
61 PRR20D  
Two-hybrid Homo sapiens
62 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
63 NOM1  
Two-hybrid Homo sapiens
64 NIP7 51388
Affinity Capture-MS Homo sapiens
65 YTHDC1  
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 PRR20B  
Two-hybrid Homo sapiens
67 PCBP1 5093
Affinity Capture-MS Homo sapiens
68 TJP2 9414
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 RPA3 6119
Proximity Label-MS Homo sapiens
70 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
71 ZFP62  
Affinity Capture-MS Homo sapiens
72 AKT1 207
Biochemical Activity Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
73 SUPT16H 11198
Biochemical Activity Homo sapiens
74 CDC42EP4  
Biochemical Activity Homo sapiens
75 RPS16 6217
Affinity Capture-MS Homo sapiens
76 DDX46 9879
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
77 PAXBP1  
Affinity Capture-MS Homo sapiens
78 YBX1 4904
Affinity Capture-MS Homo sapiens
79 NUDT21 11051
Affinity Capture-MS Homo sapiens
80 CHTOP  
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
81 RRS1 23212
Affinity Capture-MS Homo sapiens
82 MDK 4192
Biochemical Activity Homo sapiens
83 C4orf46  
Biochemical Activity Homo sapiens
84 SRSF9 8683
Biochemical Activity Homo sapiens
85 ATAT1  
Biochemical Activity Homo sapiens
86 SRSF12  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
87 PUF60 22827
Affinity Capture-MS Homo sapiens
88 TRA2B 6434
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
89 DDX27 55661
Affinity Capture-MS Homo sapiens
90 ERCC3  
Biochemical Activity Homo sapiens
91 NEIL1  
Affinity Capture-MS Homo sapiens
92 SUPT6H 6830
Affinity Capture-MS Homo sapiens
93 RPL23A 6147
Affinity Capture-MS Homo sapiens
94 LUC7L 55692
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
95 EXOSC8  
Two-hybrid Homo sapiens
96 UBE2E2  
Biochemical Activity Homo sapiens
97 LDHA 3939
Two-hybrid Homo sapiens
98 HOMER3 9454
Biochemical Activity Homo sapiens
99 LUZP4  
Two-hybrid Homo sapiens
100 NXT2  
Biochemical Activity Homo sapiens
101 ERN1  
Biochemical Activity Homo sapiens
102 KIAA0020 9933
Affinity Capture-MS Homo sapiens
103 SNURF  
Biochemical Activity Homo sapiens
104 BTF3 689
Affinity Capture-MS Homo sapiens
105 PRPF38A 84950
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
106 ENOX2  
Biochemical Activity Homo sapiens
107 THRAP3 9967
Affinity Capture-MS Homo sapiens
108 ARL6IP4  
Biochemical Activity Homo sapiens
109 RPL14 9045
Affinity Capture-MS Homo sapiens
110 URB2  
Affinity Capture-MS Homo sapiens
111 CAND1 55832
Biochemical Activity Homo sapiens
112 GPR114  
Biochemical Activity Homo sapiens
113 SRSF2 6427
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
114 SNRPF 6636
Affinity Capture-MS Homo sapiens
115 RPL32 6161
Affinity Capture-MS Homo sapiens
116 NPM2  
Biochemical Activity Homo sapiens
117 RNPS1 10921
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
118 RWDD2B  
Biochemical Activity Homo sapiens
119 DDX24 57062
Affinity Capture-MS Homo sapiens
120 PRPF38B 55119
Affinity Capture-MS Homo sapiens
121 TAF1D  
Affinity Capture-MS Homo sapiens
122 NPM1 4869
Affinity Capture-MS Homo sapiens
123 SRRM2 23524
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
124 TDP2 51567
Biochemical Activity Homo sapiens
125 RSRC1  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
126 U2AF1 7307
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
127 DDX6 1656
Biochemical Activity Homo sapiens
128 YPEL3  
Biochemical Activity Homo sapiens
129 YWHAB 7529
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
130 PFN1 5216
Proximity Label-MS Homo sapiens
131 HIST2H2AB 317772
Affinity Capture-MS Homo sapiens
132 PRPF8 10594
Co-fractionation Homo sapiens
133 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
134 RPL4 6124
Affinity Capture-MS Homo sapiens
135 RBM28 55131
Affinity Capture-MS Homo sapiens
136 DRG1 4733
Biochemical Activity Homo sapiens
137 TRA2A 29896
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
138 DNAJC2 27000
Proximity Label-MS Homo sapiens
139 ACIN1 22985
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
140 VRK1 7443
Biochemical Activity Homo sapiens
141 SNRPD1 6632
Affinity Capture-MS Homo sapiens
142 NELFE 7936
Biochemical Activity Homo sapiens
143 REXO4  
Affinity Capture-MS Homo sapiens
144 RBMX2  
Affinity Capture-MS Homo sapiens
145 LUC7L2 51631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
146 SCAF11  
Affinity Capture-MS Homo sapiens
147 MAGOH 4116
Affinity Capture-MS Homo sapiens
148 RPLP0 6175
Affinity Capture-MS Homo sapiens
149 POLB 5423
Biochemical Activity Homo sapiens
150 PPM1G 5496
Co-fractionation Homo sapiens
151 RSL1D1 26156
Affinity Capture-MS Homo sapiens
152 HMGN3  
Biochemical Activity Homo sapiens
153 FGFBP1 9982
Affinity Capture-MS Homo sapiens
154 RECQL5  
Affinity Capture-MS Homo sapiens
155 FAM76B  
Biochemical Activity Homo sapiens
156 PSMA3 5684
Biochemical Activity Homo sapiens
157 ARPC1B 10095
Biochemical Activity Homo sapiens
158 FGF12  
Biochemical Activity Homo sapiens
159 MCOLN3  
Biochemical Activity Homo sapiens
160 SETD2  
Affinity Capture-MS Homo sapiens
161 SRSF5 6430
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
162 FAM90A1  
Biochemical Activity Homo sapiens
163 MAP2K3 5606
Affinity Capture-MS Homo sapiens
164 CEBPZ  
Affinity Capture-MS Homo sapiens
165 CSAG1  
Biochemical Activity Homo sapiens
166 DDRGK1 65992
Affinity Capture-MS Homo sapiens
167 BMI1  
Affinity Capture-MS Homo sapiens
168 NOP16 51491
Biochemical Activity Homo sapiens
169 VIMP 55829
Biochemical Activity Homo sapiens
170 FTSJ3 117246
Affinity Capture-MS Homo sapiens
171 PABPC4 8761
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
172 RPL13 6137
Affinity Capture-MS Homo sapiens
173 SURF6  
Affinity Capture-MS Homo sapiens
174 HNRNPH2 3188
Affinity Capture-MS Homo sapiens
175 DIDO1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
176 ILF3 3609
Affinity Capture-MS Homo sapiens
177 FXR1 8087
Two-hybrid Homo sapiens
178 COMMD5 28991
Affinity Capture-MS Homo sapiens
179 SEC23B 10483
Biochemical Activity Homo sapiens
180 PTBP1 5725
Biochemical Activity Homo sapiens
181 C1orf35  
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
182 PTBP2  
Two-hybrid Homo sapiens
183 CHD2 1106
Biochemical Activity Homo sapiens
184 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
185 SFSWAP  
Affinity Capture-MS Homo sapiens
186 DDX39A 10212
Affinity Capture-MS Homo sapiens
187 RBM23  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
188 C16orf78  
Biochemical Activity Homo sapiens
189 NOC2L 26155
Affinity Capture-MS Homo sapiens
190 SLAIN2  
Biochemical Activity Homo sapiens
191 EGLN2  
Biochemical Activity Homo sapiens
192 RPL7A 6130
Affinity Capture-MS Homo sapiens
193 GLYR1 84656
Affinity Capture-MS Homo sapiens
194 CACNG2  
Biochemical Activity Homo sapiens
195 Rnps1  
Two-hybrid Mus musculus
196 GABARAPL1 23710
Biochemical Activity Homo sapiens
197 DBF4B 80174
Biochemical Activity Homo sapiens
198 ZNF668  
Affinity Capture-MS Homo sapiens
199 HNRNPC 3183
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
200 RPL26L1 51121
Affinity Capture-MS Homo sapiens
201 SNRPE 6635
Affinity Capture-MS Homo sapiens
202 DNAJC8 22826
Biochemical Activity Homo sapiens
203 ALMS1  
Affinity Capture-MS Homo sapiens
204 RPS19 6223
Affinity Capture-MS Homo sapiens
205 PRKAA1 5562
Biochemical Activity Homo sapiens
206 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
207 UNKL  
Two-hybrid Homo sapiens
208 SRSF8 10929
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
209 RPL10A 4736
Affinity Capture-MS Homo sapiens
210 DROSHA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
211 PAK4 10298
Biochemical Activity Homo sapiens
212 ZNF638 27332
Affinity Capture-MS Homo sapiens
213 CCDC137  
Affinity Capture-MS Homo sapiens
214 AMMECR1L 83607
Biochemical Activity Homo sapiens
215 CDK12 51755
Affinity Capture-MS Homo sapiens
216 ANOS1 3730
Affinity Capture-MS Homo sapiens
217 C17orf85  
Biochemical Activity Homo sapiens
218 RC3H1 149041
Affinity Capture-MS Homo sapiens
219 ATG16L1 55054
Affinity Capture-MS Homo sapiens
220 CACTIN  
Affinity Capture-MS Homo sapiens
221 ARGLU1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
222 PRR20C  
Two-hybrid Homo sapiens
223 RBM8A 9939
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
224 DAW1  
Biochemical Activity Homo sapiens
225 BRIX1 55299
Affinity Capture-MS Homo sapiens
226 CLK2 1196
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
227 DDX31  
Affinity Capture-MS Homo sapiens
228 SCAF1  
Affinity Capture-MS Homo sapiens
229 NSG1  
Affinity Capture-MS Homo sapiens
230 PARK2  
Affinity Capture-MS Homo sapiens
231 PPIL1 51645
Biochemical Activity Homo sapiens
232 RPS10 6204
Affinity Capture-MS Homo sapiens
233 NOP2 4839
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
234 RTF1 23168
Biochemical Activity Homo sapiens
235 RSRC2  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
236 MAPT  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
237 BARD1 580
Affinity Capture-MS Homo sapiens
238 NTRK1 4914
Affinity Capture-MS Homo sapiens
239 U2AF2 11338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
240 NSRP1  
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
241 SNRNP27  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
242 PDE7B  
Biochemical Activity Homo sapiens
243 VAV2 7410
Two-hybrid Homo sapiens
244 LCA5  
Biochemical Activity Homo sapiens
245 NKTR  
Affinity Capture-MS Homo sapiens
246 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
247 TAF7L  
Biochemical Activity Homo sapiens
248 RPL11 6135
Affinity Capture-MS Homo sapiens
249 RBBP6 5930
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
250 ZBTB2 57621
Affinity Capture-MS Homo sapiens
251 CHERP 10523
Biochemical Activity Homo sapiens
252 MRPS6  
Biochemical Activity Homo sapiens
253 LCE3D  
Biochemical Activity Homo sapiens
254 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
255 ZSCAN9  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
256 CBLN4  
Biochemical Activity Homo sapiens
257 RPL41  
Biochemical Activity Homo sapiens
258 PDCD11 22984
Affinity Capture-MS Homo sapiens
259 PSPC1 55269
Affinity Capture-MS Homo sapiens
260 FXR2 9513
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
261 ZC3H18  
Affinity Capture-MS Homo sapiens
262 MAPKAPK5 8550
Biochemical Activity Homo sapiens
263 CLASRP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
264 RPL22 6146
Biochemical Activity Homo sapiens
265 HP1BP3 50809
Affinity Capture-MS Homo sapiens
266 GPATCH8  
Affinity Capture-MS Homo sapiens
267 NSMCE4A  
Biochemical Activity Homo sapiens
268 CHUK 1147
Biochemical Activity Homo sapiens
269 HECTD1 25831
Affinity Capture-MS Homo sapiens
270 STON1 11037
Biochemical Activity Homo sapiens
271 CPSF6 11052
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
272 CLK1  
Biochemical Activity Homo sapiens
Two-hybrid Homo sapiens
273 FBXL6  
Affinity Capture-MS Homo sapiens
274 USP36  
Affinity Capture-MS Homo sapiens
275 MAGEB2 4113
Affinity Capture-MS Homo sapiens
276 SNRPA 6626
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
277 HNRNPM 4670
Affinity Capture-MS Homo sapiens
278 ABL1 25
Biochemical Activity Homo sapiens
279 RBM15 64783
Biochemical Activity Homo sapiens
280 CCDC97  
Biochemical Activity Homo sapiens
281 MKI67  
Affinity Capture-MS Homo sapiens
282 NCK2 8440
Biochemical Activity Homo sapiens
283 RNPC3  
Affinity Capture-MS Homo sapiens
284 UFL1 23376
Affinity Capture-MS Homo sapiens
285 SNIP1  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
286 CDK13 8621
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
287 PRR20E  
Two-hybrid Homo sapiens
288 AKAP17A  
Affinity Capture-MS Homo sapiens
289 FOXN3 1112
Biochemical Activity Homo sapiens
290 TAF1C  
Affinity Capture-MS Homo sapiens
291 RPL28 6158
Affinity Capture-MS Homo sapiens
292 RBM34  
Affinity Capture-MS Homo sapiens
293 U2af2 22185
Two-hybrid Mus musculus
294 LUC7L3 51747
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
295 EP300 2033
Affinity Capture-MS Homo sapiens
296 GNL2 29889
Affinity Capture-MS Homo sapiens
297 UBE2H 7328
Affinity Capture-MS Homo sapiens
298 RIT1 6016
Biochemical Activity Homo sapiens
299 COIL  
Two-hybrid Homo sapiens
300 RPS3A 6189
Affinity Capture-MS Homo sapiens
301 RIT2  
Biochemical Activity Homo sapiens
302 RPL13A 23521
Affinity Capture-MS Homo sapiens
303 CTNNBL1 56259
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
304 DHX8 1659
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
305 UTP23  
Affinity Capture-MS Homo sapiens
306 RPL15 6138
Affinity Capture-MS Homo sapiens
307 PPIA 5478
Biochemical Activity Homo sapiens
308 BUD13  
Affinity Capture-MS Homo sapiens
309 APP 351
Reconstituted Complex Homo sapiens
310 GSK3A 2931
Affinity Capture-MS Homo sapiens
311 HOXB6 3216
Two-hybrid Homo sapiens
312 UBD  
Biochemical Activity Homo sapiens
313 EVI5L  
Biochemical Activity Homo sapiens
314 HIRIP3  
Biochemical Activity Homo sapiens
315 FBXW7  
Affinity Capture-MS Homo sapiens
316 SNRPC 6631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
317 WDR12 55759
Affinity Capture-MS Homo sapiens
318 ADARB1 104
Affinity Capture-MS Homo sapiens
319 PRKRA 8575
Affinity Capture-MS Homo sapiens
320 DDX51  
Affinity Capture-MS Homo sapiens
321 SRI 6717
Biochemical Activity Homo sapiens
322 NOC3L 64318
Affinity Capture-MS Homo sapiens
323 RRP8  
Affinity Capture-MS Homo sapiens
324 NGLY1 55768
Biochemical Activity Homo sapiens
325 SON 6651
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
326 MYCN  
Affinity Capture-MS Homo sapiens
327 PRR20A  
Two-hybrid Homo sapiens
328 CASK 8573
Biochemical Activity Homo sapiens
329 TRIM41 90933
Biochemical Activity Homo sapiens
330 ARHGAP12  
Biochemical Activity Homo sapiens
331 OCEL1  
Biochemical Activity Homo sapiens
332 APOBEC3C 27350
Biochemical Activity Homo sapiens
333 SRSF6 6431
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
334 TPD52 7163
Biochemical Activity Homo sapiens
335 FOXK2  
Affinity Capture-MS Homo sapiens
336 Ube2i  
Two-hybrid Mus musculus
337 SDPR 8436
Co-fractionation Homo sapiens
338 GLTSCR2  
Affinity Capture-MS Homo sapiens
339 SRSF11 9295
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
340 ADPRH 141
Biochemical Activity Homo sapiens
341 CCM2 83605
Biochemical Activity Homo sapiens
342 PRPF4B 8899
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
343 CDK7 1022
Biochemical Activity Homo sapiens
344 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
345 CDK9 1025
Affinity Capture-MS Homo sapiens
346 CLK3  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
347 SNRNP35  
Biochemical Activity Homo sapiens
348 PNN 5411
Affinity Capture-MS Homo sapiens
349 SNRPB 6628
Affinity Capture-MS Homo sapiens
350 EPB41L4A 64097
Biochemical Activity Homo sapiens
351 SRSF1 6426
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
352 RPS6 6194
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
353 RPL3 6122
Affinity Capture-MS Homo sapiens
354 MAB21L2  
Biochemical Activity Homo sapiens
355 RBM27  
Affinity Capture-MS Homo sapiens
356 TNIP2  
Biochemical Activity Homo sapiens
357 RBM26 64062
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
358 MSI2 124540
Two-hybrid Homo sapiens
359 INO80B 83444
Affinity Capture-MS Homo sapiens
360 SRSF10 10772
Affinity Capture-MS Homo sapiens
361 LGMN 5641
Biochemical Activity Homo sapiens
362 KRAS 3845
Affinity Capture-MS Homo sapiens
363 BMP4 652
Affinity Capture-MS Homo sapiens
364 BRD3 8019
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
365 BAIAP2 10458
Biochemical Activity Homo sapiens
366 C10orf2 56652
Affinity Capture-MS Homo sapiens
367 DHX15 1665
Affinity Capture-MS Homo sapiens
368 ARRB2 409
Affinity Capture-MS Homo sapiens
369 SIRT6  
Affinity Capture-MS Homo sapiens
370 ZRANB2 9406
Biochemical Activity Homo sapiens
371 SRRM1 10250
FRET Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
372 PPIG 9360
Affinity Capture-MS Homo sapiens
373 DGCR8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
374 EIF4A3 9775
Affinity Capture-MS Homo sapiens
375 TLE4  
Biochemical Activity Homo sapiens
376 NUP50 10762
Biochemical Activity Homo sapiens
377 SDR42E1  
Biochemical Activity Homo sapiens
378 SRSF7 6432
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Biochemical Activity Homo sapiens
379 EPS8L3 79574
Biochemical Activity Homo sapiens
380 RPS8 6202
Affinity Capture-MS Homo sapiens
381 GTF2E1 2960
Biochemical Activity Homo sapiens
382 GRSF1 2926
Proximity Label-MS Homo sapiens
383 ZMAT4  
Biochemical Activity Homo sapiens
384 RPL17 6139
Affinity Capture-MS Homo sapiens
385 YPEL2 388403
Biochemical Activity Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here