Gene description for IGF2BP3
Gene name insulin-like growth factor 2 mRNA binding protein 3
Gene symbol IGF2BP3
Other names/aliases CT98
IMP-3
IMP3
KOC
KOC1
VICKZ3
Species Homo sapiens
 Database cross references - IGF2BP3
ExoCarta ExoCarta_10643
Vesiclepedia VP_10643
Entrez Gene 10643
HGNC 28868
MIM 608259
UniProt O00425  
 IGF2BP3 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for IGF2BP3
Molecular Function
    RNA binding GO:0003723 HDA
    mRNA 3'-UTR binding GO:0003730 IBA
    mRNA 3'-UTR binding GO:0003730 IDA
    protein binding GO:0005515 IPI
    translation regulator activity GO:0045182 ISS
    mRNA 5'-UTR binding GO:0048027 IDA
    N6-methyladenosine-containing RNA reader activity GO:1990247 IDA
Biological Process
    regulation of cytokine production GO:0001817 IC
    translation GO:0006412 TAS
    nervous system development GO:0007399 IBA
    anatomical structure morphogenesis GO:0009653 TAS
    negative regulation of translation GO:0017148 ISS
    mRNA transport GO:0051028 IEA
    CRD-mediated mRNA stabilization GO:0070934 IBA
    CRD-mediated mRNA stabilization GO:0070934 IDA
Subcellular Localization
    P-body GO:0000932 IDA
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    cytoplasmic stress granule GO:0010494 IDA
 Experiment description of studies that identified IGF2BP3 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
17
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
18
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
21
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
35
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IGF2BP3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZNF346  
Affinity Capture-MS Homo sapiens
2 USP10 9100
Affinity Capture-MS Homo sapiens
3 ARPC4 10093
Affinity Capture-MS Homo sapiens
4 EIF2B2 8892
Co-fractionation Homo sapiens
5 DDX17 10521
Affinity Capture-MS Homo sapiens
6 TUBB8 347688
Affinity Capture-MS Homo sapiens
7 KIF20A 10112
Affinity Capture-MS Homo sapiens
8 UBC 7316
Affinity Capture-MS Homo sapiens
9 KPNA2 3838
Affinity Capture-MS Homo sapiens
10 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 KIF23 9493
Affinity Capture-MS Homo sapiens
12 AP2A1 160
Affinity Capture-MS Homo sapiens
13 METAP2 10988
Affinity Capture-MS Homo sapiens
14 FLII 2314
Co-fractionation Homo sapiens
15 RCBTB2  
Affinity Capture-MS Homo sapiens
16 RPS9 6203
Affinity Capture-MS Homo sapiens
17 GSPT1 2935
Affinity Capture-MS Homo sapiens
18 PTCD1 26024
Affinity Capture-MS Homo sapiens
19 MNDA 4332
Affinity Capture-MS Homo sapiens
20 MECP2 4204
Affinity Capture-MS Homo sapiens
21 NMT1 4836
Co-fractionation Homo sapiens
22 RPS11 6205
Affinity Capture-MS Homo sapiens
23 RPL19 6143
Affinity Capture-MS Homo sapiens
24 RBM14 10432
Affinity Capture-MS Homo sapiens
25 NEIL3  
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
26 KIF14 9928
Affinity Capture-MS Homo sapiens
27 RBMX 27316
Affinity Capture-MS Homo sapiens
28 KLF16  
Affinity Capture-MS Homo sapiens
29 CHMP4C 92421
Affinity Capture-MS Homo sapiens
30 AURKA 6790
Affinity Capture-MS Homo sapiens
31 MRE11A 4361
Co-fractionation Homo sapiens
32 MEPCE 56257
Affinity Capture-MS Homo sapiens
33 MAP1B 4131
Affinity Capture-MS Homo sapiens
34 PURG  
Affinity Capture-MS Homo sapiens
35 PABPC1 26986
Affinity Capture-MS Homo sapiens
36 TRIM21 6737
Affinity Capture-Western Homo sapiens
37 OGT 8473
Reconstituted Complex Homo sapiens
38 RPL31 6160
Affinity Capture-MS Homo sapiens
39 MEOX2  
Two-hybrid Homo sapiens
40 BANF1 8815
Affinity Capture-MS Homo sapiens
41 YWHAQ 10971
Affinity Capture-MS Homo sapiens
42 RFC4 5984
Co-fractionation Homo sapiens
43 DBT 1629
Affinity Capture-MS Homo sapiens
44 SLC25A5 292
Affinity Capture-MS Homo sapiens
45 CNBP 7555
Affinity Capture-MS Homo sapiens
46 ANLN 54443
Affinity Capture-MS Homo sapiens
47 TLX2  
Proximity Label-MS Homo sapiens
48 TMPO 7112
Affinity Capture-MS Homo sapiens
49 WBSCR16  
Affinity Capture-MS Homo sapiens
50 LRRC59 55379
Affinity Capture-MS Homo sapiens
51 SIRT7  
Affinity Capture-MS Homo sapiens
52 MYH14 79784
Affinity Capture-MS Homo sapiens
53 ANXA1 301
Protein-peptide Homo sapiens
54 ACTBL2 345651
Affinity Capture-MS Homo sapiens
55 EIF4E 1977
Affinity Capture-MS Homo sapiens
56 EPRS 2058
Co-fractionation Homo sapiens
57 FN1 2335
Affinity Capture-MS Homo sapiens
58 PCBP1 5093
Two-hybrid Homo sapiens
59 RPA3 6119
Proximity Label-MS Homo sapiens
60 NME1 4830
Affinity Capture-MS Homo sapiens
61 NDUFA3  
Affinity Capture-MS Homo sapiens
62 RPS16 6217
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 PAIP1 10605
Affinity Capture-MS Homo sapiens
64 TLX1  
Affinity Capture-MS Homo sapiens
65 YBX1 4904
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 NUDT21 11051
Affinity Capture-MS Homo sapiens
67 WWOX 51741
Affinity Capture-MS Homo sapiens
68 APOBEC3D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 LSM14A 26065
Affinity Capture-MS Homo sapiens
70 TUBGCP3 10426
Affinity Capture-MS Homo sapiens
71 MRPS35 60488
Affinity Capture-MS Homo sapiens
72 CAPZB 832
Affinity Capture-MS Homo sapiens
73 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
74 PUF60 22827
Affinity Capture-MS Homo sapiens
75 NCL 4691
Affinity Capture-MS Homo sapiens
76 ALYREF 10189
Affinity Capture-MS Homo sapiens
77 HNRNPL 3191
Affinity Capture-MS Homo sapiens
78 CDK4 1019
Affinity Capture-RNA Homo sapiens
79 CLTA 1211
Affinity Capture-MS Homo sapiens
80 STMN3  
Affinity Capture-MS Homo sapiens
81 RPL23A 6147
Co-fractionation Homo sapiens
82 SP7  
Proximity Label-MS Homo sapiens
83 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
84 GSTP1 2950
Affinity Capture-MS Homo sapiens
85 SPRTN  
Affinity Capture-MS Homo sapiens
86 ATG5 9474
Affinity Capture-RNA Homo sapiens
87 EIF2S3 1968
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 RPS17 6218
Affinity Capture-MS Homo sapiens
89 KCTD10 83892
Affinity Capture-MS Homo sapiens
90 FMR1 2332
Affinity Capture-MS Homo sapiens
91 BTF3 689
Affinity Capture-MS Homo sapiens
92 NACA 4666
Affinity Capture-MS Homo sapiens
93 UCHL1 7345
Affinity Capture-MS Homo sapiens
94 USP16  
Co-fractionation Homo sapiens
95 RPL14 9045
Affinity Capture-MS Homo sapiens
96 EIF4A1 1973
Affinity Capture-MS Homo sapiens
97 CAND1 55832
Affinity Capture-MS Homo sapiens
98 RPS3 6188
Affinity Capture-MS Homo sapiens
99 LGALS3BP 3959
Affinity Capture-MS Homo sapiens
100 RPS18 6222
Affinity Capture-MS Homo sapiens
101 POTEE 445582
Affinity Capture-MS Homo sapiens
102 PGK1 5230
Cross-Linking-MS (XL-MS) Homo sapiens
103 RBM3 5935
Affinity Capture-MS Homo sapiens
104 G3BP2 9908
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
105 PRC1 9055
Affinity Capture-MS Homo sapiens
106 MRPS23 51649
Affinity Capture-MS Homo sapiens
107 NPM1 4869
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
108 KLF15  
Affinity Capture-MS Homo sapiens
109 MAD2L2 10459
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
110 KLF4  
Affinity Capture-MS Homo sapiens
111 DDX6 1656
Affinity Capture-MS Homo sapiens
112 RBM42  
Affinity Capture-MS Homo sapiens
113 FASTKD2  
Affinity Capture-MS Homo sapiens
114 LARP4B 23185
Affinity Capture-MS Homo sapiens
115 SNRPE 6635
Affinity Capture-MS Homo sapiens
116 SOX6  
Affinity Capture-MS Homo sapiens
117 DDX21 9188
Affinity Capture-MS Homo sapiens
118 RPL4 6124
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 DRG1 4733
Affinity Capture-MS Homo sapiens
120 HSPE1-MOB4  
Affinity Capture-MS Homo sapiens
121 RPL38 6169
Co-fractionation Homo sapiens
122 RAB2A 5862
Co-fractionation Homo sapiens
123 Rrbp1  
Affinity Capture-MS Mus musculus
124 IARS 3376
Co-fractionation Homo sapiens
125 KLF12  
Proximity Label-MS Homo sapiens
126 TUBB 203068
Affinity Capture-MS Homo sapiens
127 RPS2 6187
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 ARPC1B 10095
Affinity Capture-MS Homo sapiens
129 RC3H2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 MRPS11  
Affinity Capture-MS Homo sapiens
131 MRPL9 65005
Affinity Capture-MS Homo sapiens
132 FUS 2521
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
133 C4A 720
Affinity Capture-MS Homo sapiens
134 CDK2 1017
Affinity Capture-MS Homo sapiens
135 MYC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 TMOD3 29766
Affinity Capture-MS Homo sapiens
137 CUL7 9820
Affinity Capture-MS Homo sapiens
138 FKBP3 2287
Co-fractionation Homo sapiens
139 DDRGK1 65992
Affinity Capture-MS Homo sapiens
140 NELFB 25920
Co-fractionation Homo sapiens
141 RAE1 8480
Affinity Capture-MS Homo sapiens
142 PHGDH 26227
Affinity Capture-MS Homo sapiens
143 FAM120A 23196
Affinity Capture-MS Homo sapiens
144 PA2G4 5036
Co-fractionation Homo sapiens
145 RPL13 6137
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 MKRN1 23608
Affinity Capture-MS Homo sapiens
147 GRN 2896
Affinity Capture-MS Homo sapiens
148 SPOP  
Affinity Capture-MS Homo sapiens
149 MYL6 4637
Affinity Capture-MS Homo sapiens
150 ILF3 3609
Affinity Capture-MS Homo sapiens
151 TP53 7157
Affinity Capture-MS Homo sapiens
152 FOXP1 27086
Protein-RNA Homo sapiens
153 RPS4X 6191
Affinity Capture-MS Homo sapiens
154 RPL23 9349
Affinity Capture-MS Homo sapiens
155 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
156 HNRNPK 3190
Affinity Capture-MS Homo sapiens
157 KHDRBS2  
Affinity Capture-MS Homo sapiens
158 BCL2L1 598
Affinity Capture-MS Homo sapiens
159 EEF1D 1936
Affinity Capture-MS Homo sapiens
160 YBX3 8531
Co-fractionation Homo sapiens
161 RPL7A 6130
Affinity Capture-MS Homo sapiens
162 RPL27 6155
Cross-Linking-MS (XL-MS) Homo sapiens
163 C1QBP 708
Affinity Capture-MS Homo sapiens
164 RPS29 6235
Affinity Capture-MS Homo sapiens
165 PTRF 284119
Affinity Capture-MS Homo sapiens
166 PRMT1 3276
Affinity Capture-MS Homo sapiens
167 MRPS9 64965
Affinity Capture-MS Homo sapiens
168 MYL12B 103910
Affinity Capture-MS Homo sapiens
169 MVP 9961
Affinity Capture-MS Homo sapiens
170 MRPS27 23107
Affinity Capture-MS Homo sapiens
171 RPSA 3921
Affinity Capture-MS Homo sapiens
172 RPL26L1 51121
Co-fractionation Homo sapiens
173 IDH1 3417
Affinity Capture-MS Homo sapiens
174 MARCKS 4082
Affinity Capture-MS Homo sapiens
175 MRPL30  
Affinity Capture-MS Homo sapiens
176 KRT17 3872
Co-fractionation Homo sapiens
177 YWHAE 7531
Affinity Capture-MS Homo sapiens
178 ABCF1 23
Co-fractionation Homo sapiens
179 LARP1B 55132
Affinity Capture-MS Homo sapiens
180 USP11 8237
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
181 HNRNPUL2 221092
Co-fractionation Homo sapiens
182 DIMT1 27292
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
183 RPL10A 4736
Affinity Capture-MS Homo sapiens
184 GSPT2 23708
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
185 CRYZ 1429
Co-fractionation Homo sapiens
186 SOGA1 140710
Affinity Capture-RNA Homo sapiens
187 EIF3B 8662
Affinity Capture-MS Homo sapiens
188 YARS2  
Affinity Capture-MS Homo sapiens
189 SUPV3L1 6832
Affinity Capture-MS Homo sapiens
190 SRP14 6727
Affinity Capture-MS Homo sapiens
191 HMGA2 8091
Affinity Capture-MS Homo sapiens
192 MRPL39 54148
Affinity Capture-MS Homo sapiens
193 PABPC4 8761
Affinity Capture-MS Homo sapiens
194 MTERF3  
Affinity Capture-MS Homo sapiens
195 RBM8A 9939
Affinity Capture-MS Homo sapiens
196 MAP2 4133
Co-fractionation Homo sapiens
197 LIN28A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
198 MDH2 4191
Affinity Capture-MS Homo sapiens
199 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
200 MRPS25 64432
Affinity Capture-MS Homo sapiens
201 PARK2  
Affinity Capture-MS Homo sapiens
202 RPS10 6204
Affinity Capture-MS Homo sapiens
203 RPL5 6125
Affinity Capture-MS Homo sapiens
204 MKRN2 23609
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
205 TUBA1B 10376
Affinity Capture-MS Homo sapiens
206 NTRK1 4914
Affinity Capture-MS Homo sapiens
207 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 RPA4  
Proximity Label-MS Homo sapiens
209 RAB3GAP1 22930
Affinity Capture-MS Homo sapiens
210 DHX9 1660
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
211 TRUB2  
Affinity Capture-MS Homo sapiens
212 HNRNPA3 220988
Affinity Capture-MS Homo sapiens
213 ACTG1 71
Affinity Capture-MS Homo sapiens
214 RPL11 6135
Affinity Capture-MS Homo sapiens
215 CKAP5 9793
Affinity Capture-MS Homo sapiens
216 RBM47 54502
Affinity Capture-MS Homo sapiens
217 RPL21 6144
Affinity Capture-MS Homo sapiens
218 FBXO6 26270
Affinity Capture-MS Homo sapiens
219 ACE2 59272
Affinity Capture-Western Homo sapiens
220 SOX15  
Affinity Capture-MS Homo sapiens
221 PRR3  
Affinity Capture-MS Homo sapiens
222 CBX6  
Affinity Capture-MS Homo sapiens
223 NEFL 4747
Affinity Capture-MS Homo sapiens
224 PSPC1 55269
Affinity Capture-MS Homo sapiens
225 RPS13 6207
Affinity Capture-MS Homo sapiens
226 RPL22 6146
Affinity Capture-MS Homo sapiens
227 ACTB 60
Affinity Capture-MS Homo sapiens
228 RPL18 6141
Affinity Capture-MS Homo sapiens
229 AKAP1 8165
Proximity Label-MS Homo sapiens
230 RBMS2 5939
Affinity Capture-MS Homo sapiens
231 TUBB2A 7280
Affinity Capture-MS Homo sapiens
232 EIF2S1 1965
Affinity Capture-MS Homo sapiens
233 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
234 CCT8 10694
Affinity Capture-MS Homo sapiens
235 RPL6 6128
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
236 DDX3X 1654
Affinity Capture-MS Homo sapiens
237 SNRPA 6626
Affinity Capture-MS Homo sapiens
238 HNRNPM 4670
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
239 TUBB3 10381
Affinity Capture-MS Homo sapiens
240 G3BP1 10146
Affinity Capture-MS Homo sapiens
241 TRIM25 7706
Affinity Capture-Western Homo sapiens
242 UFL1 23376
Affinity Capture-MS Homo sapiens
243 SH3BGR  
Affinity Capture-MS Homo sapiens
244 MRPS18B 28973
Affinity Capture-MS Homo sapiens
245 RTCB 51493
Co-fractionation Homo sapiens
246 RPS7 6201
Affinity Capture-MS Homo sapiens
247 RPL8 6132
Affinity Capture-MS Homo sapiens
248 C14orf166 51637
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
249 MRPS31  
Affinity Capture-MS Homo sapiens
250 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
251 SSRP1 6749
Affinity Capture-MS Homo sapiens
252 SRSF7 6432
Affinity Capture-MS Homo sapiens
253 IGF2BP2 10644
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
254 NHLH1  
Proximity Label-MS Homo sapiens
255 UBE2H 7328
Affinity Capture-MS Homo sapiens
256 PIH1D2  
Two-hybrid Homo sapiens
257 IGF2BP1 10642
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
258 AP2B1 163
Affinity Capture-MS Homo sapiens
259 QARS 5859
Co-fractionation Homo sapiens
260 RPS3A 6189
Affinity Capture-MS Homo sapiens
261 PTBP1 5725
Affinity Capture-MS Homo sapiens
262 RPL30 6156
Affinity Capture-MS Homo sapiens
263 PPIE 10450
Affinity Capture-MS Homo sapiens
264 RPL37A 6168
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
265 Ybx1 22608
Affinity Capture-MS Mus musculus
266 NGRN  
Affinity Capture-MS Homo sapiens
267 POM121  
Affinity Capture-MS Homo sapiens
268 RPUSD4 84881
Affinity Capture-MS Homo sapiens
269 ILF2 3608
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
270 COPS5 10987
Affinity Capture-MS Homo sapiens
271 RPS20 6224
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
272 DYRK1A 1859
Affinity Capture-MS Homo sapiens
273 MRPS5 64969
Affinity Capture-MS Homo sapiens
274 FBXW7  
Affinity Capture-MS Homo sapiens
275 IMPDH2 3615
Affinity Capture-MS Homo sapiens
276 C8orf82  
Proximity Label-MS Homo sapiens
277 CALM3 808
Affinity Capture-MS Homo sapiens
278 SNRPC 6631
Affinity Capture-MS Homo sapiens
279 HMGA1 3159
Affinity Capture-MS Homo sapiens
280 SRP68 6730
Affinity Capture-MS Homo sapiens
281 CDK1 983
Affinity Capture-MS Homo sapiens
282 MYCN  
Affinity Capture-MS Homo sapiens
283 PPP3R1 5534
Affinity Capture-MS Homo sapiens
284 OBSL1 23363
Affinity Capture-MS Homo sapiens
285 CPEB1  
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
286 EDC4 23644
Co-fractionation Homo sapiens
287 RPS23 6228
Affinity Capture-MS Homo sapiens
288 SRP9 6726
Affinity Capture-MS Homo sapiens
289 POM121C  
Affinity Capture-MS Homo sapiens
290 MRPL32 64983
Affinity Capture-MS Homo sapiens
291 ECT2 1894
Affinity Capture-MS Homo sapiens
292 RB1CC1 9821
Affinity Capture-MS Homo sapiens
293 MRPS34 65993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 NONO 4841
Affinity Capture-MS Homo sapiens
295 STAU1 6780
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
296 DDX5 1655
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
297 FOXK2  
Affinity Capture-MS Homo sapiens
298 DDX1 1653
Co-fractionation Homo sapiens
299 CEBPA  
Protein-peptide Homo sapiens
300 ELAVL2 1993
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
301 PPAN 56342
Affinity Capture-MS Homo sapiens
302 RPLP2 6181
Affinity Capture-MS Homo sapiens
303 FANCD2  
Affinity Capture-MS Homo sapiens
304 CUL3 8452
Affinity Capture-MS Homo sapiens
305 UPF1 5976
Affinity Capture-MS Homo sapiens
306 SNRPB 6628
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
307 GCSH 2653
Affinity Capture-MS Homo sapiens
308 RPS8 6202
Affinity Capture-MS Homo sapiens
309 MRPL15 29088
Affinity Capture-MS Homo sapiens
310 MRPL1  
Affinity Capture-MS Homo sapiens
311 PRKACA 5566
Affinity Capture-MS Homo sapiens
312 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
313 PABPC5 140886
Affinity Capture-MS Homo sapiens
314 EIF2B3 8891
Co-fractionation Homo sapiens
315 LGMN 5641
Co-fractionation Homo sapiens
316 CLTC 1213
Affinity Capture-MS Homo sapiens
317 CCND1 595
Affinity Capture-RNA Homo sapiens
318 GNB2L1 10399
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
319 MDM2  
Affinity Capture-MS Homo sapiens
320 CCDC8  
Affinity Capture-MS Homo sapiens
321 GSN 2934
Affinity Capture-MS Homo sapiens
322 MYO1C 4641
Affinity Capture-MS Homo sapiens
323 MRPL42  
Affinity Capture-MS Homo sapiens
324 SLC25A11 8402
Affinity Capture-MS Homo sapiens
325 ERH 2079
Affinity Capture-MS Homo sapiens
326 HECTD4 283450
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
327 ZNF746  
Affinity Capture-MS Homo sapiens
328 NUFIP2 57532
Affinity Capture-MS Homo sapiens
329 HNRNPA2B1 3181
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
330 PDCD6 10016
Co-fractionation Homo sapiens
331 RPS15 6209
Affinity Capture-MS Homo sapiens
332 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
Affinity Capture-MS Homo sapiens
333 KIAA1429 25962
Affinity Capture-MS Homo sapiens
334 MOV10 4343
Affinity Capture-RNA Homo sapiens
335 MRPL13  
Affinity Capture-MS Homo sapiens
336 HECTD1 25831
Affinity Capture-MS Homo sapiens
337 TRIM31  
Affinity Capture-MS Homo sapiens
338 PINK1  
Affinity Capture-MS Homo sapiens
339 RPS6 6194
Affinity Capture-MS Homo sapiens
340 GRSF1 2926
Proximity Label-MS Homo sapiens
341 XRCC6 2547
Affinity Capture-MS Homo sapiens
342 NDUFAF4 29078
Co-fractionation Homo sapiens
343 HNRNPU 3192
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
344 C9orf72  
Affinity Capture-MS Homo sapiens
345 LAPTM4A 9741
Co-fractionation Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here