Gene description for CRIPT
Gene name cysteine-rich PDZ-binding protein
Gene symbol CRIPT
Other names/aliases HSPC139
Species Homo sapiens
 Database cross references - CRIPT
ExoCarta ExoCarta_9419
Entrez Gene 9419
HGNC 14312
MIM 604594
UniProt Q9P021  
 CRIPT identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for CRIPT
Molecular Function
    scaffold protein binding GO:0097110 IDA
    PDZ domain binding GO:0030165 IDA
    protein complex binding GO:0032403 ISS
    protein binding GO:0005515 IPI
    microtubule binding GO:0008017 ISS
Biological Process
    protein localization to microtubule GO:0035372 ISS
    regulation of postsynaptic density protein 95 clustering GO:1902897 ISS
    cytoplasmic microtubule organization GO:0031122 ISS
    establishment of protein localization GO:0045184 ISS
Subcellular Localization
    postsynaptic density GO:0014069 ISS
    dendritic spine GO:0043197 ISS
    dendritic shaft GO:0043198 ISS
    cell junction GO:0030054 IEA
    cytoplasm GO:0005737 IEA
    nucleus GO:0005634 IDA
    nucleolus GO:0005730 IDA
    dendrite GO:0030425 ISS
    neuronal cell body GO:0043025 ISS
 Experiment description of studies that identified CRIPT in exosomes
Experiment ID 126
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for CRIPT
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DLG1 1739
Reconstituted Complex Homo sapiens
2 DLG4  
Reconstituted Complex Homo sapiens
3 DLG3 1741
Invivo Homo sapiens
Invitro Homo sapiens
Two-hybrid Homo sapiens
4 TUBB2A 7280
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CRIPT is involved
No pathways found

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