Gene description for ALG9
Gene name ALG9, alpha-1,2-mannosyltransferase
Gene symbol ALG9
Other names/aliases CDG1L
DIBD1
LOH11CR1J
Species Homo sapiens
 Database cross references - ALG9
ExoCarta ExoCarta_79796
Vesiclepedia VP_79796
Entrez Gene 79796
HGNC 15672
MIM 606941
UniProt Q9H6U8  
 ALG9 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for ALG9
Molecular Function
    alpha-1,2-mannosyltransferase activity GO:0000026 IBA
    alpha-1,2-mannosyltransferase activity GO:0000026 TAS
    dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity GO:0052918 IGI
    dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity GO:0052926 IGI
Biological Process
    protein N-linked glycosylation GO:0006487 IBA
    protein N-linked glycosylation GO:0006487 IMP
    dolichol-linked oligosaccharide biosynthetic process GO:0006488 IGI
    dolichol-linked oligosaccharide biosynthetic process GO:0006488 TAS
Subcellular Localization
    endoplasmic reticulum membrane GO:0005789 IBA
    endoplasmic reticulum membrane GO:0005789 TAS
    membrane GO:0016020 HDA
    lumenal side of endoplasmic reticulum membrane GO:0098553 IC
 Experiment description of studies that identified ALG9 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ALG9
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 C15orf32  
Affinity Capture-MS Homo sapiens
2 GLT6D1  
Affinity Capture-MS Homo sapiens
3 CANX 821
Affinity Capture-MS Homo sapiens
4 HTR3A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 KLRC2  
Affinity Capture-MS Homo sapiens
6 SLC17A2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 FASN 2194
Negative Genetic Homo sapiens
8 NRROS  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 BHMT 635
Two-hybrid Homo sapiens
10 CLGN 1047
Affinity Capture-MS Homo sapiens
11 CHRNA4  
Affinity Capture-MS Homo sapiens
12 TTYH1  
Affinity Capture-MS Homo sapiens
13 GABRE  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 LDLRAD1  
Affinity Capture-MS Homo sapiens
15 SIDT2 51092
Affinity Capture-MS Homo sapiens
16 PRSS21  
Affinity Capture-MS Homo sapiens
17 CHST6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 GABRA3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 HPN  
Affinity Capture-MS Homo sapiens
20 ENPP6 133121
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 TMPRSS3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 ASIC4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 HTR3C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 TMPRSS12  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 KLRC4  
Affinity Capture-MS Homo sapiens
26 CHST5  
Affinity Capture-MS Homo sapiens
27 TMED6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 STS 412
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 HSPB1 3315
Affinity Capture-MS Homo sapiens
30 GRIA3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 GPR114  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 ATP1B3 483
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 HNRNPF 3185
Co-fractionation Homo sapiens
34 WNT3  
Affinity Capture-MS Homo sapiens
35 CORO1C 23603
Co-fractionation Homo sapiens
36 CHRNB2  
Affinity Capture-MS Homo sapiens
37 GGT7 2686
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 CHPT1  
Affinity Capture-MS Homo sapiens
39 CHRNB4  
Affinity Capture-MS Homo sapiens
40 RPA3 6119
Proximity Label-MS Homo sapiens
41 ATP2A1 487
Proximity Label-MS Homo sapiens
42 APOC3 345
Affinity Capture-MS Homo sapiens
43 NCEH1 57552
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 TCTN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
45 LDLR 3949
Negative Genetic Homo sapiens
46 DPM2 8818
Affinity Capture-MS Homo sapiens
47 RPN1 6184
Proximity Label-MS Homo sapiens
48 KIR2DS3  
Affinity Capture-MS Homo sapiens
49 MPPE1 65258
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 IL17RC 84818
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 KLRC1  
Affinity Capture-MS Homo sapiens
52 ST14 6768
Affinity Capture-MS Homo sapiens
53 UPK1A 11045
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 SLC22A4 6583
Affinity Capture-MS Homo sapiens
55 KIR2DS5  
Affinity Capture-MS Homo sapiens
56 CCDC47 57003
Affinity Capture-MS Homo sapiens
57 SCNN1D  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 KCNK16  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 TMPRSS13  
Affinity Capture-MS Homo sapiens
60 ZACN  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 CHRND  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 PNLDC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here