Gene description for SCNN1B
Gene name	sodium channel, non voltage gated 1 beta subunit
Gene symbol	SCNN1B
Other names/aliases	BESC1 ENaCb ENaCbeta SCNEB
Species	Homo sapiens
Database cross references - SCNN1B
ExoCarta	ExoCarta_6338
Vesiclepedia	VP_6338
Entrez Gene	6338
HGNC	10600
MIM	600760
UniProt	P51168
SCNN1B identified in sEVs derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for SCNN1B

Molecular Function     sodium channel activity GO:0005272 IDA     protein binding GO:0005515 IPI     ligand-gated sodium channel activity GO:0015280 IEA     WW domain binding GO:0050699 IPI Biological Process     leukocyte activation involved in inflammatory response GO:0002269 IEA     neutrophil activation involved in immune response GO:0002283 IEA     renal system process GO:0003014 IEA     intracellular sodium ion homeostasis GO:0006883 IDA     regulation of blood pressure GO:0008217 NAS     response to xenobiotic stimulus GO:0009410 IEA     gene expression GO:0010467 IEA     artery smooth muscle contraction GO:0014824 IEA     response to food GO:0032094 IEA     aldosterone metabolic process GO:0032341 IEA     erythrocyte homeostasis GO:0034101 IEA     multicellular organism growth GO:0035264 IEA     sodium ion transmembrane transport GO:0035725 IBA     sodium ion transmembrane transport GO:0035725 IDA     epithelial fluid transport GO:0042045 IEA     multicellular organismal-level water homeostasis GO:0050891 IDA     sensory perception of salty taste GO:0050914 NAS     sensory perception of sour taste GO:0050915 NAS     potassium ion homeostasis GO:0055075 IEA     sodium ion homeostasis GO:0055078 IDA     mucus secretion GO:0070254 IEA     neutrophil-mediated killing of bacterium GO:0070944 IEA     cellular response to acidic pH GO:0071468 IDA     sodium ion import across plasma membrane GO:0098719 IDA     cellular response to aldosterone GO:1904045 NAS     cellular response to vasopressin GO:1904117 NAS Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 NAS     plasma membrane GO:0005886 TAS     external side of plasma membrane GO:0009897 IEA     apical plasma membrane GO:0016324 IDA     apical plasma membrane GO:0016324 ISS     cytoplasmic vesicle membrane GO:0030659 IEA     sodium channel complex GO:0034706 IBA     sodium channel complex GO:0034706 IDA     sodium channel complex GO:0034706 IPI     extracellular exosome GO:0070062 IDA