Gene description for SEPT5
Gene name
septin 5
Gene symbol
SEPT5
Other names/aliases
CDCREL CDCREL-1 CDCREL1 H5 HCDCREL-1 PNUTL1
Species
Homo sapiens
Database cross references - SEPT5
ExoCarta
ExoCarta_5413
Entrez Gene
5413
HGNC
9164
MIM
602724
UniProt
Q99719
SEPT5 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells
25944692
Thymus
23844026
Gene ontology annotations for SEPT5
Experiment description of studies that identified SEPT5 in exosomes
1
Experiment ID
224
ISEV standards
✔
EM|AFM
EV Biophysical techniques
✔
Alix|TSG101
EV Cytosolic markers
✔
CD63|CD81
EV Membrane markers
✔
GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25944692
Organism
Homo sapiens
Experiment description
Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors
Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name
Oncotarget
Publication year
2015
Sample
Neuroblastoma cells
Sample name
SH-SY5Y
Isolation/purification methods
Differential centrifugation Ultracentrifugation OptiPrep density gradient
Flotation density
1.10 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry Western blotting
2
Experiment ID
217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23844026
Organism
Homo sapiens
Experiment description
Characterization of human thymic exosomes.
Authors
Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name
PLoS One
Publication year
2013
Sample
Thymus
Sample name
Normal-Thymus
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for SEPT5
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
MYST2
Two-hybrid
Homo sapiens
2
LSM8
Two-hybrid
Homo sapiens
3
PFN2
5217
Two-hybrid
Homo sapiens
4
STX1A
6804
Invivo
Homo sapiens
Invitro
Homo sapiens
5
PARK2
Invivo
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
Biochemical Activity
Homo sapiens
6
SEPT8
23176
Invivo
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
Reconstituted Complex
Homo sapiens
Affinity Capture-Western
Homo sapiens
Affinity Capture-Western
Homo sapiens
Two-hybrid
Homo sapiens
7
STX4
6810
Invitro
Homo sapiens
8
SEPT2
4735
Invivo
Homo sapiens
Invitro
Homo sapiens
View the network
image/svg+xml
Pathways in which SEPT5 is involved
No pathways found