Gene description for CXCL8
Gene name	chemokine (C-X-C motif) ligand 8
Gene symbol	CXCL8
Other names/aliases	GCP-1 GCP1 IL8 LECT LUCT LYNAP MDNCF MONAP NAF NAP-1 NAP1
Species	Homo sapiens
Database cross references - CXCL8
ExoCarta	ExoCarta_3576
Entrez Gene	3576
HGNC	6025
MIM	146930
UniProt	P10145
CXCL8 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for CXCL8

Molecular Function     interleukin-8 receptor binding GO:0005153 IPI     chemokine activity GO:0008009 TAS     protein binding GO:0005515 IPI Biological Process     immune response GO:0006955 IBA     PERK-mediated unfolded protein response GO:0036499 TAS     inflammatory response GO:0006954 TAS     intracellular signal transduction GO:0035556 IDA     receptor internalization GO:0031623 IDA     positive regulation of angiogenesis GO:0045766 IDA     response to molecule of bacterial origin GO:0002237 IDA     calcium-mediated signaling GO:0019722 TAS     G-protein coupled receptor signaling pathway GO:0007186 TAS     chemokine-mediated signaling pathway GO:0070098 IBA     negative regulation of cell proliferation GO:0008285 TAS     cell cycle arrest GO:0007050 IDA     cellular response to fibroblast growth factor stimulus GO:0044344 IEP     cellular response to interleukin-1 GO:0071347 IEP     chemotaxis GO:0006935 TAS     neutrophil activation GO:0042119 TAS     movement of cell or subcellular component GO:0006928 TAS     cellular protein metabolic process GO:0044267 TAS     embryonic digestive tract development GO:0048566 IEP     endoplasmic reticulum unfolded protein response GO:0030968 TAS     angiogenesis GO:0001525 TAS     response to endoplasmic reticulum stress GO:0034976 IDA     regulation of cell adhesion GO:0030155 IDA     negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 IDA     regulation of single stranded viral RNA replication via double stranded DNA intermediate GO:0045091 IDA     cellular response to lipopolysaccharide GO:0071222 IDA     signal transduction GO:0007165 TAS     induction of positive chemotaxis GO:0050930 IGI     cellular response to tumor necrosis factor GO:0071356 IEP     positive regulation of neutrophil chemotaxis GO:0090023 TAS     neutrophil chemotaxis GO:0030593 IGI Subcellular Localization     intracellular GO:0005622 TAS     extracellular space GO:0005615 IEA     extracellular region GO:0005576 TAS