Gene description for NPTXR
Gene name neuronal pentraxin receptor
Gene symbol NPTXR
Other names/aliases NPR
Species Homo sapiens
 Database cross references - NPTXR
ExoCarta ExoCarta_23467
Vesiclepedia VP_23467
Entrez Gene 23467
HGNC 7954
MIM 609474
UniProt O95502  
 NPTXR identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for NPTXR
Molecular Function
    metal ion binding GO:0046872 IEA
Subcellular Localization
    membrane GO:0016020 IEA
    glutamatergic synapse GO:0098978 IDA
    glutamatergic synapse GO:0098978 IMP
 Experiment description of studies that identified NPTXR in exosomes
1
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for NPTXR
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PARD3B 117583
Affinity Capture-MS Homo sapiens
2 NPTX1  
Affinity Capture-MS Homo sapiens
3 FAM160B1 57700
Affinity Capture-MS Homo sapiens
4 AQP6  
Affinity Capture-MS Homo sapiens
5 SIAE 54414
Affinity Capture-MS Homo sapiens
6 ERP44 23071
Affinity Capture-MS Homo sapiens
7 EMID1  
Affinity Capture-MS Homo sapiens
8 MFAP4 4239
Affinity Capture-MS Homo sapiens
9 CYB5D2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 HOOK2  
Affinity Capture-MS Homo sapiens
11 IL5RA  
Affinity Capture-MS Homo sapiens
12 FN1 2335
Affinity Capture-MS Homo sapiens
13 HSPA5 3309
Affinity Capture-MS Homo sapiens
14 SFTPC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 ACACA 31
Affinity Capture-MS Homo sapiens
16 FBXO2 26232
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 PHC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 PTX4  
Affinity Capture-MS Homo sapiens
19 ACACB 32
Affinity Capture-MS Homo sapiens
20 CORO1A 11151
Affinity Capture-MS Homo sapiens
21 CST9L  
Affinity Capture-MS Homo sapiens
22 FBXO11  
Affinity Capture-MS Homo sapiens
23 SEPN1 57190
Affinity Capture-MS Homo sapiens
24 NPTX2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which NPTXR is involved
No pathways found





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