Experiment description of studies that identified Atxn2 in sEVs

1 Experiment ID 15 MISEV standards ✔ EM Biophysical techniques ✔ CD63 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule mrna Identification method Microarray PubMed ID 17486113     Organism Mus musculus Homo sapiens Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO" Journal name NCB Publication year 2007 Sample Mast cells Sample name MC9 Bone marrow-derived mast cells HMC-1 Isolation/purification methods Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.11-1.21 g/mL Molecules identified in the study Protein mRNA miRNA Methods used in the study Mass spectrometry [MALDI TOF] Western blotting Microarray miRCURY LNA Array

Protein-protein interactions for Atxn2

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Rps3 27050 Co-fractionation Mus musculus 2 Ncbp1 433702 Co-fractionation Mus musculus 3 Sh3gl2   Affinity Capture-Western Mus musculus Affinity Capture-Western Mus musculus 4 Rpl13a 22121 Co-fractionation Mus musculus 5 Rps4x 20102 Co-fractionation Mus musculus 6 Pls3 102866 Affinity Capture-Western Mus musculus 7 Obscn   Cross-Linking-MS (XL-MS) Mus musculus 8 Rps8 20116 Co-fractionation Mus musculus 9 Ybx1 22608 Co-fractionation Mus musculus 10 Fmr1   Affinity Capture-MS Mus musculus 11 Foxp3   Affinity Capture-MS Mus musculus 12 Hnrnpu 51810 Co-fractionation Mus musculus 13 Lcp1 18826 Affinity Capture-Western Mus musculus 14 Rps6 20104 Co-fractionation Mus musculus 15 Hnrnpl 15388 Co-fractionation Mus musculus 16 Src 20779 Affinity Capture-Western Mus musculus 17 Atg5   Affinity Capture-MS Mus musculus 18 Sh3kbp1 58194 Affinity Capture-Western Mus musculus Co-fractionation Mus musculus 19 Sra1   Co-fractionation Mus musculus 20 Syncrip 56403 Co-fractionation Mus musculus 21 Rps3a1 20091 Co-fractionation Mus musculus 22 Rpl26 19941 Co-fractionation Mus musculus 23 Rplp0 11837 Co-fractionation Mus musculus 24 Ilf3 16201 Co-fractionation Mus musculus 25 Rptor   Co-fractionation Mus musculus 26 Tsg101 22088 Co-fractionation Mus musculus 27 Cbl 12402 Affinity Capture-Western Mus musculus View the network

Pathways in which Atxn2 is involved

No pathways found