Gene description for Dhfr
Gene name	dihydrofolate reductase
Gene symbol	Dhfr
Other names/aliases	8430436I03Rik AA607882 AI662710 AW555094
Species	Mus musculus
Database cross references - Dhfr
ExoCarta	ExoCarta_13361
Entrez Gene	13361
UniProt	P00375
Dhfr identified in exosomes derived from the following tissue/cell type
Pancreatic cells	19351151

Gene ontology annotations for Dhfr

Molecular Function     dihydrofolate reductase activity GO:0004146 ISO     dihydrofolic acid binding GO:0051871 ISO     RNA binding GO:0003723 IEA     oxidoreductase activity GO:0016491 IEA     NADP binding GO:0050661 ISO     drug binding GO:0008144 ISO     mRNA binding GO:0003729 ISO Biological Process     nucleotide biosynthetic process GO:0009165 IEA     response to methotrexate GO:0031427 IEA     dihydrofolate metabolic process GO:0046452 ISO     oxidation-reduction process GO:0055114 IDA     tetrahydrofolate metabolic process GO:0046653 ISO     tetrahydrofolate biosynthetic process GO:0046654 ISO     one-carbon metabolic process GO:0006730 IEA     glycine biosynthetic process GO:0006545 IEA