Gene description for Csde1
Gene name cold shock domain containing E1, RNA binding
Gene symbol Csde1
Other names/aliases AA960392
BC016898
D3Jfr1
mKIAA0885
unr
Species Mus musculus
 Database cross references - Csde1
ExoCarta ExoCarta_229663
Vesiclepedia VP_229663
Entrez Gene 229663
UniProt Q91W50  
 Csde1 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
Mast cells 17486113    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Csde1
Molecular Function
    RNA stem-loop binding GO:0035613 IEA
    RNA stem-loop binding GO:0035613 ISO
    lncRNA binding GO:0106222 IEA
    RISC complex binding GO:1905172 IDA
    RISC complex binding GO:1905172 ISO
Biological Process
    stress granule assembly GO:0034063 ISO
    stress granule assembly GO:0034063 ISS
    CRD-mediated mRNA stabilization GO:0070934 ISO
    nuclear-transcribed mRNA catabolic process, no-go decay GO:0070966 IEA
    nuclear-transcribed mRNA catabolic process, no-go decay GO:0070966 ISO
    IRES-dependent viral translational initiation GO:0075522 IEA
    IRES-dependent viral translational initiation GO:0075522 ISO
    negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:1900152 ISO
    positive regulation of cytoplasmic translation GO:2000767 ISO
Subcellular Localization
    P-body GO:0000932 IEA
    mitochondrial inner membrane GO:0005743 HDA
    Golgi apparatus GO:0005794 IEA
    Golgi apparatus GO:0005794 ISO
    cytosol GO:0005829 ISO
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    cytoplasmic stress granule GO:0010494 IEA
    CRD-mediated mRNA stability complex GO:0070937 IEA
    CRD-mediated mRNA stability complex GO:0070937 ISO
    mCRD-mediated mRNA stability complex GO:0106002 ISO
 Experiment description of studies that identified Csde1 in exosomes
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
3
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Csde1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PLEKHA3  
Affinity Capture-MS Homo sapiens
2 Tdrd3  
Co-fractionation Mus musculus
3 EIF4H 7458
Affinity Capture-MS Homo sapiens
4 DUSP11  
Affinity Capture-MS Homo sapiens
5 Tmem173  
Proximity Label-MS Mus musculus
6 Fzr1  
Affinity Capture-MS Mus musculus
7 Atxn1  
Affinity Capture-MS Mus musculus
8 Hoxd3  
Two-hybrid Mus musculus
9 Kctd13  
Affinity Capture-MS Mus musculus
10 DDX41 51428
Affinity Capture-MS Homo sapiens
11 TXNDC9 10190
Affinity Capture-MS Homo sapiens
12 ABHD16A 7920
Affinity Capture-MS Homo sapiens
13 TMEM131  
Affinity Capture-MS Homo sapiens
14 LCOR 84458
Affinity Capture-MS Homo sapiens
15 Unk  
Affinity Capture-RNA Mus musculus
16 Nfe2  
Two-hybrid Mus musculus
17 PABPC4L 132430
Affinity Capture-MS Homo sapiens
18 Fancd2  
Affinity Capture-MS Mus musculus
19 STRAP 11171
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Csde1 is involved
No pathways found





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