Gene description for KIF3C
Gene name kinesin family member 3C
Gene symbol KIF3C
Other names/aliases -
Species Homo sapiens
 Database cross references - KIF3C
ExoCarta ExoCarta_3797
Entrez Gene 3797
HGNC 6321
MIM 602845
UniProt O14782  
 KIF3C identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for KIF3C
Molecular Function
    ATP binding GO:0005524 IEA
    microtubule motor activity GO:0003777 IBA
    microtubule binding GO:0008017 IEA
    ATPase activity GO:0016887 IBA
    motor activity GO:0003774 TAS
Biological Process
    antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0019886 TAS
    microtubule-based movement GO:0007018 TAS
    metabolic process GO:0008152 TAS
    organelle transport along microtubule GO:0072384 IEA
    blood coagulation GO:0007596 TAS
    organelle organization GO:0006996 TAS
    cytoskeleton-dependent intracellular transport GO:0030705 IBA
Subcellular Localization
    cytosol GO:0005829 TAS
    microtubule GO:0005874 IEA
    primary cilium GO:0072372 TAS
    ciliary tip GO:0097542 TAS
    kinesin complex GO:0005871 IEA
 Experiment description of studies that identified KIF3C in exosomes
Experiment ID 224
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for KIF3C
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PSMA2 5683
Invivo Homo sapiens
Invitro Homo sapiens
View the network image/svg+xml
 Pathways in which KIF3C is involved
Intraflagellar transport TAS Reactome
Kinesins TAS Reactome
MHC class II antigen presentation TAS Reactome

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