Gene description for MCF2L2
Gene name MCF.2 cell line derived transforming sequence-like 2
Gene symbol MCF2L2
Other names/aliases ARHGEF22
Species Homo sapiens
 Database cross references - MCF2L2
ExoCarta ExoCarta_23101
Vesiclepedia VP_23101
Entrez Gene 23101
HGNC 30319
UniProt Q86YR7  
 MCF2L2 identified in exosomes derived from the following tissue/cell type
Urine 21595033    
Urine 21595033    
Urine 21595033    
 Gene ontology annotations for MCF2L2
Molecular Function
    guanyl-nucleotide exchange factor activity GO:0005085 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 IEA
 Experiment description of studies that identified MCF2L2 in exosomes
1
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for MCF2L2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MAT2A 4144
Affinity Capture-MS Homo sapiens
2 LBR 3930
Affinity Capture-MS Homo sapiens
3 EXOSC6 118460
Affinity Capture-MS Homo sapiens
4 SLIRP 81892
Affinity Capture-MS Homo sapiens
5 CHRAC1  
Affinity Capture-MS Homo sapiens
6 ANKFY1 51479
Affinity Capture-MS Homo sapiens
7 NUP205 23165
Affinity Capture-MS Homo sapiens
8 SNRPE 6635
Affinity Capture-MS Homo sapiens
9 MAX  
Affinity Capture-MS Homo sapiens
10 LDHB 3945
Affinity Capture-MS Homo sapiens
11 MGA  
Affinity Capture-MS Homo sapiens
12 MRPS31  
Affinity Capture-MS Homo sapiens
13 RIF1  
Affinity Capture-MS Homo sapiens
14 DPY30 84661
Affinity Capture-MS Homo sapiens
15 SKP1 6500
Affinity Capture-MS Homo sapiens
16 KIF20A 10112
Affinity Capture-MS Homo sapiens
17 SRSF5 6430
Affinity Capture-MS Homo sapiens
18 TMEM263 90488
Affinity Capture-MS Homo sapiens
19 TXNDC12 51060
Affinity Capture-MS Homo sapiens
20 CDK6 1021
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 STOML2 30968
Affinity Capture-MS Homo sapiens
22 SIRT1  
Affinity Capture-MS Homo sapiens
23 SF3B5 83443
Affinity Capture-MS Homo sapiens
24 SFXN1 94081
Affinity Capture-MS Homo sapiens
25 RANBP9 10048
Affinity Capture-MS Homo sapiens
26 BIRC6 57448
Affinity Capture-MS Homo sapiens
27 HIC2 23119
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 CIRBP 1153
Affinity Capture-MS Homo sapiens
29 CHCHD2  
Affinity Capture-MS Homo sapiens
30 RPS29 6235
Affinity Capture-MS Homo sapiens
31 PSMD12 5718
Affinity Capture-MS Homo sapiens
32 MRPS26 64949
Affinity Capture-MS Homo sapiens
33 MRPS14  
Affinity Capture-MS Homo sapiens
34 SERPINH1 871
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which MCF2L2 is involved
No pathways found





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