Gene description for OAF
Gene name OAF homolog (Drosophila)
Gene symbol OAF
Other names/aliases NS5ATP13TP2
Species Homo sapiens
 Database cross references - OAF
ExoCarta ExoCarta_220323
Vesiclepedia VP_220323
Entrez Gene 220323
HGNC 28752
UniProt Q86UD1  
 OAF identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for OAF
 Experiment description of studies that identified OAF in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
6
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for OAF
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 LY86  
Affinity Capture-MS Homo sapiens
2 FCGR3B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 CCL22 6367
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 EPDR1 54749
Affinity Capture-MS Homo sapiens
5 NAAA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 ADAM18  
Affinity Capture-MS Homo sapiens
7 C1QTNF9B  
Affinity Capture-MS Homo sapiens
8 OIT3 170392
Affinity Capture-MS Homo sapiens
9 SIAE 54414
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 TMEM87A 25963
Affinity Capture-MS Homo sapiens
11 KLK5 25818
Affinity Capture-MS Homo sapiens
12 FSTL4  
Affinity Capture-MS Homo sapiens
13 MFAP4 4239
Affinity Capture-MS Homo sapiens
14 TSHR 7253
Affinity Capture-MS Homo sapiens
15 EFNA2  
Affinity Capture-MS Homo sapiens
16 SFTA2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 TNFSF11  
Affinity Capture-MS Homo sapiens
18 ASIC4  
Affinity Capture-MS Homo sapiens
19 PDGFRA 5156
Affinity Capture-MS Homo sapiens
20 BTLA  
Affinity Capture-MS Homo sapiens
21 ATP1B4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 CBLN4  
Affinity Capture-MS Homo sapiens
23 GRIN2C 2905
Affinity Capture-MS Homo sapiens
24 BOC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 CEACAM21  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 FCN3 8547
Affinity Capture-MS Homo sapiens
27 SLURP1  
Affinity Capture-MS Homo sapiens
28 IL5RA  
Affinity Capture-MS Homo sapiens
29 ARL4C 10123
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 ELSPBP1  
Affinity Capture-MS Homo sapiens
31 EPHA7 2045
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 ST3GAL4 6484
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 MSMB  
Affinity Capture-MS Homo sapiens
34 TM2D3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 SIRPD  
Affinity Capture-MS Homo sapiens
36 BRICD5  
Affinity Capture-MS Homo sapiens
37 SDF2L1 23753
Affinity Capture-MS Homo sapiens
38 LCN9  
Affinity Capture-MS Homo sapiens
39 LYPD1  
Affinity Capture-MS Homo sapiens
40 DKKL1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 FAM174A 345757
Affinity Capture-MS Homo sapiens
42 FIGF 2277
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 CST11  
Affinity Capture-MS Homo sapiens
44 CD160  
Affinity Capture-MS Homo sapiens
45 TRAC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 HLA-DQB2  
Affinity Capture-MS Homo sapiens
47 EDN3  
Affinity Capture-MS Homo sapiens
48 NXPH3  
Affinity Capture-MS Homo sapiens
49 F9 2158
Affinity Capture-MS Homo sapiens
50 CFB 629
Affinity Capture-MS Homo sapiens
51 BAGE2  
Affinity Capture-MS Homo sapiens
52 ST14 6768
Affinity Capture-MS Homo sapiens
53 TMEM106A  
Affinity Capture-MS Homo sapiens
54 TRAV20  
Affinity Capture-MS Homo sapiens
55 LYPD4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 PLA2G10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 ISLR 3671
Affinity Capture-MS Homo sapiens
58 TMPRSS13  
Affinity Capture-MS Homo sapiens
59 ST8SIA4 7903
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which OAF is involved
No pathways found





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