Experiment description of studies that identified Hba in sEVs

1 Experiment ID 303 MISEV standards ✔ EM Biophysical techniques ✔ Cd63|Cd81|Cd9 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33431899     Organism Mus musculus Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG." Journal name Nat Commun Publication year 2021 Sample Faeces Sample name Intestinal epithelial cells - C57BL/6 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation Flotation density - Molecules identified in the study Protein Lipid miRNA Methods used in the study Western blotting Mass spectrometry Immunofluorescence miRNA array HPLC

2 Experiment ID 304 MISEV standards ✔ EM Biophysical techniques ✔ Cd63|Cd81|Cd9 Enriched markers ✘ Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 33431899     Organism Mus musculus Experiment description High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance Authors "Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG." Journal name Nat Commun Publication year 2021 Sample Faeces Sample name Intestinal epithelial cells - C57BL/6 Isolation/purification methods Differential centrifugation Ultracentrifugation Sucrose density gradient centrifugation Flotation density - Molecules identified in the study Protein Lipid miRNA Methods used in the study Western blotting Mass spectrometry Immunofluorescence miRNA array HPLC

Protein-protein interactions for Hba

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Rps27a 78294 Co-fractionation Mus musculus 2 Rps18 20084 Co-fractionation Mus musculus 3 Rps10 67097 Co-fractionation Mus musculus 4 Rps4x 20102 Co-fractionation Mus musculus 5 Rps2 16898 Co-fractionation Mus musculus 6 Rps8 20116 Co-fractionation Mus musculus 7 Rps23 66475 Co-fractionation Mus musculus 8 Rps19 20085 Co-fractionation Mus musculus 9 Rps6 20104 Co-fractionation Mus musculus 10 Rps7 20115 Co-fractionation Mus musculus 11 Rps11 27207 Co-fractionation Mus musculus 12 Rps9 76846 Co-fractionation Mus musculus 13 Rps15a 267019 Co-fractionation Mus musculus 14 Rps15 20054 Co-fractionation Mus musculus 15 Rps3a1 20091 Co-fractionation Mus musculus 16 Rps13 68052 Co-fractionation Mus musculus 17 Fancd2   Affinity Capture-MS Mus musculus 18 Rps14 20044 Co-fractionation Mus musculus 19 Rps27 57294 Co-fractionation Mus musculus 20 Tia1   Affinity Capture-MS Mus musculus 21 Rps20 67427 Co-fractionation Mus musculus 22 Rps12 20042 Co-fractionation Mus musculus View the network

Pathways in which Hba is involved

No pathways found