Gene description for L3HYPDH
Gene name L-3-hydroxyproline dehydratase (trans-)
Gene symbol L3HYPDH
Other names/aliases C14orf149
Species Homo sapiens
 Database cross references - L3HYPDH
ExoCarta ExoCarta_112849
Vesiclepedia VP_112849
Entrez Gene 112849
HGNC 20488
MIM 614811
UniProt Q96EM0  
 L3HYPDH identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for L3HYPDH
Molecular Function
    hydro-lyase activity GO:0016836 IBA
    hydro-lyase activity GO:0016836 IDA
    proline racemase activity GO:0018112 IDA
    trans-L-3-hydroxyproline dehydratase activity GO:0050346 IEA
 Experiment description of studies that identified L3HYPDH in exosomes
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for L3HYPDH
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ALDH7A1 501
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
3 UTRN 7402
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 THUMPD3 25917
Affinity Capture-MS Homo sapiens
5 KLK5 25818
Affinity Capture-MS Homo sapiens
6 SLC39A4 55630
Affinity Capture-MS Homo sapiens
7 ACOT9 23597
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 DDX19B 11269
Affinity Capture-MS Homo sapiens
9 POLR3C 10623
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 RPS14 6208
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 RNASE13  
Affinity Capture-MS Homo sapiens
12 RPL22L1 200916
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 NKIRAS2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
14 CCNE2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 TCAF1 9747
Affinity Capture-MS Homo sapiens
16 MUT 4594
Affinity Capture-MS Homo sapiens
17 DIXDC1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 CDK2 1017
Affinity Capture-MS Homo sapiens
19 UHMK1  
Affinity Capture-MS Homo sapiens
20 CPZ 8532
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 HELZ 9931
Affinity Capture-MS Homo sapiens
22 RDH13  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 GSTK1 373156
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 IP6K3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 CHEK1  
Affinity Capture-MS Homo sapiens
26 MISP 126353
Affinity Capture-MS Homo sapiens
27 SNTB2 6645
Affinity Capture-MS Homo sapiens
28 SRP14 6727
Affinity Capture-MS Homo sapiens
29 WDFY1 57590
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which L3HYPDH is involved
No pathways found





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