Gene description for SFXN1
Gene name sideroflexin 1
Gene symbol SFXN1
Other names/aliases -
Species Homo sapiens
 Database cross references - SFXN1
ExoCarta ExoCarta_94081
Vesiclepedia VP_94081
Entrez Gene 94081
HGNC 16085
MIM 615569
UniProt Q9H9B4  
 SFXN1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
 Gene ontology annotations for SFXN1
Molecular Function
    protein binding GO:0005515 IPI
    monoatomic ion transmembrane transporter activity GO:0015075 IEA
    L-alanine transmembrane transporter activity GO:0015180 IDA
    L-serine transmembrane transporter activity GO:0015194 IDA
    transmembrane transporter activity GO:0022857 IBA
Biological Process
    one-carbon metabolic process GO:0006730 IDA
    iron ion transport GO:0006826 IEA
    L-alanine transport GO:0015808 IDA
    L-serine transport GO:0015825 IDA
    erythrocyte differentiation GO:0030218 IEA
    monoatomic ion transmembrane transport GO:0034220 IEA
    serine import into mitochondrion GO:0140300 IBA
    serine import into mitochondrion GO:0140300 IDA
Subcellular Localization
    mitochondrion GO:0005739 HTP
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 IBA
    mitochondrial inner membrane GO:0005743 IDA
 Experiment description of studies that identified SFXN1 in sEVs
1
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 412
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 414
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 407
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
14
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
15
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
16
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
18
Experiment ID 405
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 417
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 411
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 418
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 413
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 406
MISEV standards
EM
Biophysical techniques
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
25
Experiment ID 415
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
28
Experiment ID 408
MISEV standards
EM
Biophysical techniques
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX|ACTB
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
29
Experiment ID 409
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
30
Experiment ID 416
MISEV standards
EM
Biophysical techniques
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 191
MISEV standards
Biophysical techniques
Alix|CD81|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
32
Experiment ID 410
MISEV standards
EM
Biophysical techniques
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for SFXN1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 ATP6V1B2 526
Co-fractionation Homo sapiens
3 AFG3L2 10939
Proximity Label-MS Homo sapiens
4 UQCRFS1 7386
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
5 SPRTN  
Affinity Capture-MS Homo sapiens
6 SLC10A6  
Two-hybrid Homo sapiens
7 ETFA 2108
Proximity Label-MS Homo sapiens
8 RAB1A 5861
Co-fractionation Homo sapiens
9 CPOX 1371
Proximity Label-MS Homo sapiens
10 ACOT7 11332
Affinity Capture-MS Homo sapiens
11 MPC2 25874
Proximity Label-MS Homo sapiens
12 ADCK2  
Proximity Label-MS Homo sapiens
13 ACOT9 23597
Co-fractionation Homo sapiens
14 DHX30 22907
Proximity Label-MS Homo sapiens
15 SLC25A13 10165
Proximity Label-MS Homo sapiens
16 CKMT1A 548596
Proximity Label-MS Homo sapiens
17 NDUFB5 4711
Proximity Label-MS Homo sapiens
18 NDUFB10 4716
Proximity Label-MS Homo sapiens
19 SPSB4  
Affinity Capture-MS Homo sapiens
20 APOE 348
Co-fractionation Homo sapiens
21 BASP1 10409
Proximity Label-MS Homo sapiens
22 LACTB 114294
Proximity Label-MS Homo sapiens
23 NDUFA4 4697
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
24 PNKD  
Proximity Label-MS Homo sapiens
25 SLC25A24 29957
Proximity Label-MS Homo sapiens
26 ATP5L 10632
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
27 FAM162A 26355
Proximity Label-MS Homo sapiens
28 LRPPRC 10128
Proximity Label-MS Homo sapiens
29 KIAA1429 25962
Affinity Capture-MS Homo sapiens
30 C9orf78 51759
Affinity Capture-MS Homo sapiens
31 AK2 204
Proximity Label-MS Homo sapiens
32 MGST1 4257
Co-fractionation Homo sapiens
33 SYT6  
Affinity Capture-MS Homo sapiens
34 OGDH 4967
Co-fractionation Homo sapiens
35 PRDX3 10935
Co-fractionation Homo sapiens
36 COX11  
Proximity Label-MS Homo sapiens
37 PRKCDBP 112464
Co-fractionation Homo sapiens
38 IARS2 55699
Proximity Label-MS Homo sapiens
39 COQ9  
Affinity Capture-MS Homo sapiens
40 PTPMT1 114971
Affinity Capture-MS Homo sapiens
41 CYB5R1 51706
Co-fractionation Homo sapiens
42 TIMMDC1  
Proximity Label-MS Homo sapiens
43 TIMM17B  
Proximity Label-MS Homo sapiens
44 MMD  
Two-hybrid Homo sapiens
45 TIMM23 100287932
Proximity Label-MS Homo sapiens
46 CHCHD10  
Affinity Capture-MS Homo sapiens
47 KIAA1191  
Proximity Label-MS Homo sapiens
48 ABCD3 5825
Proximity Label-MS Homo sapiens
49 TMEM129  
Affinity Capture-MS Homo sapiens
50 TRAP1 10131
Proximity Label-MS Homo sapiens
51 CIDEB  
Two-hybrid Homo sapiens
52 EWSR1 2130
Co-fractionation Homo sapiens
53 CIT 11113
Affinity Capture-MS Homo sapiens
54 DNAJB1 3337
Affinity Capture-MS Homo sapiens
55 PRC1 9055
Affinity Capture-MS Homo sapiens
56 ATP5O 539
Co-fractionation Homo sapiens
57 PGRMC2 10424
Two-hybrid Homo sapiens
58 FAM136A 84908
Proximity Label-MS Homo sapiens
59 COIL  
Proximity Label-MS Homo sapiens
60 C12orf73  
Proximity Label-MS Homo sapiens
61 ARHGAP19  
Affinity Capture-MS Homo sapiens
62 MYCBP2 23077
Proximity Label-MS Homo sapiens
63 ATG16L1 55054
Affinity Capture-MS Homo sapiens
64 SLC25A25  
Proximity Label-MS Homo sapiens
65 TOMM7 54543
Co-fractionation Homo sapiens
66 PSMB10 5699
Affinity Capture-MS Homo sapiens
67 SLC30A9 10463
Proximity Label-MS Homo sapiens
68 MECP2 4204
Affinity Capture-MS Homo sapiens
69 MAVS 57506
Proximity Label-MS Homo sapiens
70 TIMM50 92609
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
71 SERBP1 26135
Affinity Capture-MS Homo sapiens
72 NDUFV3 4731
Proximity Label-MS Homo sapiens
73 UQCRQ 27089
Co-fractionation Homo sapiens
74 NCSTN 23385
Affinity Capture-MS Homo sapiens
75 SLC25A3 5250
Co-fractionation Homo sapiens
76 ATP5I 521
Proximity Label-MS Homo sapiens
77 LAMTOR1 55004
Proximity Label-MS Homo sapiens
78 CMC4  
Proximity Label-MS Homo sapiens
79 ADSL 158
Affinity Capture-MS Homo sapiens
80 MCF2L2 23101
Affinity Capture-MS Homo sapiens
81 KLF16  
Affinity Capture-MS Homo sapiens
82 TPM3P4  
Co-fractionation Homo sapiens
83 PARL  
Proximity Label-MS Homo sapiens
84 TAP1 6890
Co-fractionation Homo sapiens
85 SFXN2  
Proximity Label-MS Homo sapiens
86 ATAD3B 83858
Proximity Label-MS Homo sapiens
87 STOML2 30968
Co-fractionation Homo sapiens
88 FCER1G 2207
Two-hybrid Homo sapiens
89 ATP5A1 498
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
90 TMEM14B  
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
91 UBQLN1 29979
Co-fractionation Homo sapiens
92 HCCS 3052
Proximity Label-MS Homo sapiens
93 COX15 1355
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
94 SLC16A7 9194
Two-hybrid Homo sapiens
95 NAA50 80218
Proximity Label-MS Homo sapiens
96 SFXN4  
Proximity Label-MS Homo sapiens
97 TMEM126A 84233
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
98 EXOG 9941
Proximity Label-MS Homo sapiens
99 PARK2  
Affinity Capture-MS Homo sapiens
100 PHB 5245
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
101 NDUFB11 54539
Proximity Label-MS Homo sapiens
102 STOM 2040
Two-hybrid Homo sapiens
103 SFXN3 81855
Co-fractionation Homo sapiens
104 ACOT2 10965
Proximity Label-MS Homo sapiens
105 NDUFA8 4702
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
106 OPTN 10133
Affinity Capture-MS Homo sapiens
107 STAU1 6780
Affinity Capture-MS Homo sapiens
108 MICU2 221154
Proximity Label-MS Homo sapiens
109 ATF2  
Affinity Capture-MS Homo sapiens
110 LETM1 3954
Proximity Label-MS Homo sapiens
111 DIABLO 56616
Proximity Label-MS Homo sapiens
112 COA7  
Proximity Label-MS Homo sapiens
113 TBC1D32 221322
Proximity Label-MS Homo sapiens
114 PGAM5 192111
Proximity Label-MS Homo sapiens
115 SLC25A20 788
Co-fractionation Homo sapiens
116 TDRP  
Proximity Label-MS Homo sapiens
117 USMG5 84833
Co-fractionation Homo sapiens
118 PMAIP1  
Affinity Capture-MS Homo sapiens
119 TTC19  
Proximity Label-MS Homo sapiens
120 NTRK1 4914
Affinity Capture-MS Homo sapiens
121 TOMM20 9804
Co-fractionation Homo sapiens
122 SNAP29 9342
Proximity Label-MS Homo sapiens
123 PTGES2 80142
Proximity Label-MS Homo sapiens
124 TMEM126B 55863
Proximity Label-MS Homo sapiens
125 HUWE1 10075
Affinity Capture-MS Homo sapiens
126 CYC1 1537
Proximity Label-MS Homo sapiens
127 UQCRC1 7384
Co-fractionation Homo sapiens
128 ACTB 60
Co-fractionation Homo sapiens
129 BCL6  
Affinity Capture-MS Homo sapiens
130 CHCHD6 84303
Proximity Label-MS Homo sapiens
131 TMEM56  
Two-hybrid Homo sapiens
132 HECTD1 25831
Affinity Capture-MS Homo sapiens
133 TOMM22 56993
Proximity Label-MS Homo sapiens
134 TRIAP1  
Proximity Label-MS Homo sapiens
135 AGPS 8540
Co-fractionation Homo sapiens
136 ACOX1 51
Co-fractionation Homo sapiens
137 SCN3B  
Two-hybrid Homo sapiens
138 HDAC5 10014
Affinity Capture-MS Homo sapiens
139 ATP5B 506
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
140 COX4I1 1327
Proximity Label-MS Homo sapiens
141 CD3EAP  
Proximity Label-MS Homo sapiens
142 ENDOG  
Proximity Label-MS Homo sapiens
143 TMEM14C 51522
Co-fractionation Homo sapiens
144 Sumo3  
Affinity Capture-MS Mus musculus
145 C15orf48  
Affinity Capture-MS Homo sapiens
146 IMMP1L  
Proximity Label-MS Homo sapiens
147 ACAT1 38
Co-fractionation Homo sapiens
148 ZBTB2 57621
Affinity Capture-MS Homo sapiens
149 APLNR  
Affinity Capture-MS Homo sapiens
150 GFER  
Proximity Label-MS Homo sapiens
151 HADHB 3032
Co-fractionation Homo sapiens
152 HADHA 3030
Co-fractionation Homo sapiens
153 DDI1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 AIFM1 9131
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
155 C10orf107  
Affinity Capture-MS Homo sapiens
156 C19orf52  
Proximity Label-MS Homo sapiens
157 ICAM1 3383
Co-fractionation Homo sapiens
158 NDUFA13 51079
Proximity Label-MS Homo sapiens
159 LRRC59 55379
Co-fractionation Homo sapiens
160 SDHA 6389
Affinity Capture-MS Homo sapiens
161 AGK 55750
Proximity Label-MS Homo sapiens
162 UQCRC2 7385
Co-fractionation Homo sapiens
163 CD274 29126
Affinity Capture-MS Homo sapiens
164 ASS1 445
Affinity Capture-MS Homo sapiens
165 ATP5F1 515
Co-fractionation Homo sapiens
166 TXN 7295
Co-fractionation Homo sapiens
167 UQCC3  
Proximity Label-MS Homo sapiens
168 FKBP8 23770
Proximity Label-MS Homo sapiens
169 HSD17B10 3028
Proximity Label-MS Homo sapiens
170 ARF6 382
Proximity Label-MS Homo sapiens
171 HSD17B13  
Two-hybrid Homo sapiens
172 COX6B1 1340
Proximity Label-MS Homo sapiens
173 VARS2  
Proximity Label-MS Homo sapiens
174 GHITM 27069
Proximity Label-MS Homo sapiens
175 SUZ12  
Affinity Capture-MS Homo sapiens
176 TMEM242  
Proximity Label-MS Homo sapiens
177 OCIAD1 54940
Proximity Label-MS Homo sapiens
178 GLUD1 2746
Proximity Label-MS Homo sapiens
179 TOMM70A 9868
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
180 FASN 2194
Negative Genetic Homo sapiens
181 MAPK6  
Affinity Capture-MS Homo sapiens
182 SOAT1 6646
Affinity Capture-MS Homo sapiens
183 HSPA9 3313
Proximity Label-MS Homo sapiens
184 CHCHD3 54927
Proximity Label-MS Homo sapiens
185 RPA3 6119
Proximity Label-MS Homo sapiens
186 APOOL 139322
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
187 CLPB 81570
Proximity Label-MS Homo sapiens
188 LMNB1 4001
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
189 COX2 4513
Proximity Label-MS Homo sapiens
190 TIMM8B 26521
Proximity Label-MS Homo sapiens
191 OCIAD2 132299
Proximity Label-MS Homo sapiens
192 DLST 1743
Affinity Capture-MS Homo sapiens
193 SLC10A1  
Two-hybrid Homo sapiens
194 RPA4  
Proximity Label-MS Homo sapiens
195 SCO1  
Proximity Label-MS Homo sapiens
196 MYEF2 50804
Affinity Capture-MS Homo sapiens
197 RCN2 5955
Co-fractionation Homo sapiens
198 STARD7 56910
Proximity Label-MS Homo sapiens
199 RNF2  
Affinity Capture-MS Homo sapiens
200 BMI1  
Affinity Capture-MS Homo sapiens
201 VDAC1 7416
Affinity Capture-MS Homo sapiens
202 XRCC3  
Affinity Capture-MS Homo sapiens
203 HAX1  
Proximity Label-MS Homo sapiens
204 ISLR 3671
Affinity Capture-MS Homo sapiens
205 RHOB 388
Proximity Label-MS Homo sapiens
206 ILF2 3608
Co-fractionation Homo sapiens
207 AKAP1 8165
Proximity Label-MS Homo sapiens
Proximity Label-MS Homo sapiens
208 UBXN4 23190
Proximity Label-MS Homo sapiens
209 SCCPDH 51097
Co-fractionation Homo sapiens
210 CCDC8  
Affinity Capture-MS Homo sapiens
211 TMX2 51075
Two-hybrid Homo sapiens
212 GBAS 2631
Co-fractionation Homo sapiens
213 IMMT 10989
Proximity Label-MS Homo sapiens
214 DEPDC1B 55789
Affinity Capture-MS Homo sapiens
215 MRPL42  
Affinity Capture-MS Homo sapiens
216 CCDC58 131076
Proximity Label-MS Homo sapiens
217 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
218 PHB2 11331
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
219 OMA1  
Proximity Label-MS Homo sapiens
220 TMEM65 157378
Proximity Label-MS Homo sapiens
221 ILF3 3609
Co-fractionation Homo sapiens
222 UBA5 79876
Affinity Capture-MS Homo sapiens
223 PGRMC1 10857
Affinity Capture-MS Homo sapiens
224 ICT1 3396
Affinity Capture-MS Homo sapiens
225 CDCA3 83461
Proximity Label-MS Homo sapiens
226 DNAJA2 10294
Proximity Label-MS Homo sapiens
227 ZNF746  
Affinity Capture-MS Homo sapiens
228 COX19 90639
Proximity Label-MS Homo sapiens
229 SERAC1 84947
Proximity Label-MS Homo sapiens
230 MICU3  
Proximity Label-MS Homo sapiens
231 COX16  
Proximity Label-MS Homo sapiens
232 OPA1 4976
Proximity Label-MS Homo sapiens
233 PDHA1 5160
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
234 NGEF  
Affinity Capture-MS Homo sapiens
235 SSR1 6745
Co-fractionation Homo sapiens
236 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
237 MDH2 4191
Proximity Label-MS Homo sapiens
238 CHCHD4  
Proximity Label-MS Homo sapiens
239 SURF4 6836
Proximity Label-MS Homo sapiens
240 MICU1 10367
Proximity Label-MS Homo sapiens
241 SHMT2 6472
Proximity Label-MS Homo sapiens
242 MTHFD1 4522
Co-fractionation Homo sapiens
243 SLC25A12 8604
Proximity Label-MS Homo sapiens
244 C11orf52 91894
Proximity Label-MS Homo sapiens
245 WIF1 11197
Affinity Capture-MS Homo sapiens
246 ATAD3A 55210
Proximity Label-MS Homo sapiens
247 EXD2  
Proximity Label-MS Homo sapiens
248 APOO 79135
Proximity Label-MS Homo sapiens
249 COQ2  
Affinity Capture-MS Homo sapiens
250 SMIM12  
Proximity Label-MS Homo sapiens
251 LONP1 9361
Proximity Label-MS Homo sapiens
252 TSC22D1 8848
Affinity Capture-MS Homo sapiens
253 GPD2 2820
Proximity Label-MS Homo sapiens
254 HLA-DPA1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
255 ATP6V1E1 529
Co-fractionation Homo sapiens
256 RAB7A 7879
Co-fractionation Homo sapiens
257 ATP1A1 476
Proximity Label-MS Homo sapiens
258 CYB5R3 1727
Co-fractionation Homo sapiens
259 Ranbp2  
Affinity Capture-MS Mus musculus
260 LDLR 3949
Positive Genetic Homo sapiens
261 YME1L1 10730
Proximity Label-MS Homo sapiens
262 C9orf72  
Affinity Capture-MS Homo sapiens
263 SMIM20  
Proximity Label-MS Homo sapiens
264 TIMM44 10469
Proximity Label-MS Homo sapiens
265 USP30  
Proximity Label-MS Homo sapiens
266 ARHGEF10L 55160
Affinity Capture-MS Homo sapiens
267 CYCS 54205
Proximity Label-MS Homo sapiens
268 TIMM13 26517
Proximity Label-MS Homo sapiens
269 CUL4A 8451
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
270 EP300 2033
Affinity Capture-MS Homo sapiens
271 SCO2  
Proximity Label-MS Homo sapiens
272 COX6C 1345
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SFXN1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here