Gene description for MEN1
Gene name	multiple endocrine neoplasia I
Gene symbol	MEN1
Other names/aliases	MEAI SCG2
Species	Homo sapiens
Database cross references - MEN1
ExoCarta	ExoCarta_4221
Vesiclepedia	VP_4221
Entrez Gene	4221
HGNC	7010
MIM	613733
UniProt	O00255
MEN1 identified in sEVs derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for MEN1

Molecular Function     four-way junction DNA binding GO:0000400 IDA     Y-form DNA binding GO:0000403 IBA     Y-form DNA binding GO:0000403 IDA     transcription cis-regulatory region binding GO:0000976 IBA     transcription cis-regulatory region binding GO:0000976 IDA     chromatin binding GO:0003682 IBA     double-stranded DNA binding GO:0003690 IDA     protein binding GO:0005515 IPI     protein-macromolecule adaptor activity GO:0030674 IDA     phosphoprotein binding GO:0051219 IPI     R-SMAD binding GO:0070412 IPI Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IDA     MAPK cascade GO:0000165 IDA     negative regulation of protein phosphorylation GO:0001933 IDA     osteoblast development GO:0002076 IGI     DNA repair GO:0006281 NAS     regulation of transcription by RNA polymerase II GO:0006357 IBA     DNA damage response GO:0006974 IDA     negative regulation of cell population proliferation GO:0008285 IBA     negative regulation of cell population proliferation GO:0008285 IDA     response to UV GO:0009411 IDA     response to gamma radiation GO:0010332 IDA     positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 IMP     negative regulation of DNA-binding transcription factor activity GO:0043433 IDA     T-helper 2 cell differentiation GO:0045064 IDA     negative regulation of osteoblast differentiation GO:0045668 IGI     negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045736 IMP     negative regulation of cell cycle GO:0045786 IBA     negative regulation of cell cycle GO:0045786 IDA     transcription initiation-coupled chromatin remodeling GO:0045815 IMP     negative regulation of DNA-templated transcription GO:0045892 IDA     positive regulation of transcription by RNA polymerase II GO:0045944 IMP     negative regulation of JNK cascade GO:0046329 IDA Subcellular Localization     chromosome, telomeric region GO:0000781 ISS     chromatin GO:0000785 IBA     chromatin GO:0000785 IDA     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     cytoplasm GO:0005737 IDA     endoplasmic reticulum lumen GO:0005788 TAS     cytosol GO:0005829 IDA     cytosol GO:0005829 TAS     nuclear matrix GO:0016363 IDA     transcription repressor complex GO:0017053 IPI     cleavage furrow GO:0032154 IDA     protein-containing complex GO:0032991 IDA     histone methyltransferase complex GO:0035097 IBA     histone methyltransferase complex GO:0035097 IDA     MLL1/2 complex GO:0044665 IPI     MLL1 complex GO:0071339 IPI